Protein Alignment CG14736 and Phb2

DIOPT Version :8

• Sequence 1: NP_001287293.1
• Gene: CG14736 / 41466
• FlyBaseID: FBgn0037986
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_031557.2
• Gene: Phb2 / 12034
• MGIID: 102520
• Length: 299
• Species: Mus musculus
• Alignment Length: 231
• Identity: 53/232 (23%)
• Similarity: 105/232 (45%)
• Gaps: 46/232 (20%)

  Fly    93 RLGRLRKG-LRGPGLVFILPCIDETHRVDMRTDVTNVRPQDVL----TKDSVTITVNAVVYYCIY 152
            |:|.:::. :...||.|.:|........|:|     .||:.:.    :||...:.::..|   :.
Mouse    54 RIGGVQQDTILAEGLHFRIPWFQYPIIYDIR-----ARPRKISSPTGSKDLQMVNISLRV---LS 110

  Fly   153 SP----IDSIIQ---VDDAKQATQLISQVTLRNIVGSKTLNVLLTSRQQLSREIQQAVAGITYRW 210
            .|    :.|:.|   :|..::....|....|:::|.....:.|:|.|.|:|..|::.:......:
Mouse   111 RPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDF 175

  Fly   211 GVRVERVDVMDITLPTSLERSLASEAEAV----------------REARAKIILAEGELKASKAL 259
            .:.::.|.:.:::.  |.|.:.|.||:.|                :|.|.||:.||||.:|:|.|
Mouse   176 SLILDDVAITELSF--SREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKML 238

  Fly   260 KEASDVMSENKITLQLRHLQILSSIA-----SERRV 290
            .||   :|:|...::||.::...:|:     |:.|:
Mouse   239 GEA---LSKNPGYIKLRKIRAAQNISKTIATSQNRI 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14736	NP_001287293.1	PHB	78..225	CDD:214581	27/144 (19%)
		SPFH_like	100..305	CDD:302763	51/225 (23%)
Phb2	NP_031557.2	Necessary for transcriptional repression. {ECO:0000250|UniProtKB:Q99623}	19..49
		SPFH_prohibitin	40..235	CDD:259799	42/191 (22%)
		Necessary for transcriptional repression. {ECO:0000250|UniProtKB:Q99623}	150..174		6/24 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900