Protein Alignment: CG12213 and RNF214

• Sequence 1: NP_001097754.1
• Gene: CG12213
• FlyBaseID: FBgn0260742
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001070707.1
• Gene: RNF214
• HGNCID: 25335
• Length: 703
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 91/400 (23%)
• Similarity: 164/400 (41%)
• Gaps: 60/400 (15%)

  Fly    34 SQHQLDESRAFQEGLSVQMQSLNAEKLTAEKRMSALRSEKMTLQEQYEGQLAEALQKQHDTEH-- 96
            |..:|.::.|.|.........:|.:: ..||.:..:.:|:..|:|:|:    |.|.||...|:
Human   195 SSLKLSQNIAVQTDFKTADSEVNTDQ-DIEKNLDKMMTERTLLKERYQ----EVLDKQRQVENQL 254

  Fly    97 -----ALQEKFDAQVEKYK--LLEIKYTNLEAEFVKSKKKHIEDTNAFDQKLQKVLADLHKDKAS 154
                 .||::.:.:::.::  |..|:...::.|  ::|||..::...|.||.|.:.|::.|....
Human   255 QVQLKQLQQRREEEMKNHQEILKAIQDVTIKRE--ETKKKIEKEKKEFLQKEQDLKAEIEKLCEK 317

  Fly   155 KEREVAAWKEKLDKLQ-RDGEHKIHALEATIAEFKTNC--------NYVPKVQPAEAPVQGHQQQ 210
            ..|||  |:.:||:|: :|||...:.:|.|...:|...        ..|.|::.||...:.|...
Human   318 GRREV--WEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTY 380

  Fly   211 LNKPAEQMPTTHHSNPAQLAHS---IEKPRNEKSFDAQVQVSEGLYRIGGGVNLLATNPKQNL-- 270
            |......:.|.......:...:   |.|......|::.:|    |.|.|..::.|...|...|
Human   381 LKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQ----LVRNGAKLSSLPQIPTPTLPP 441

  Fly   271 TNASTNFTLKSNGDGTQEQPQL-PLQPFAVSN-NHSLILNSVE----NFQIVPKSVSEKQQQEEP 329
            ..:.|:|.|:.    .|..|.| |..||::.. ...:::.|.:    :|.|:..::|:..|
Human   442 PPSETDFMLQV----FQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPILNPALSQPSQ---- 498

  Fly   330 QLSGGPVSPLSAPRKSSTQASVGSASDKKAGDAPNASVAPK-----VSSSGLPPLAVPPAKTERK 389
                 |.|||......::.......|.......|.||:.|.     |.:|...|...|..|.|:.
Human   499 -----PSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGVKASAETPRPQPVDKLEKI 558

  Fly   390 LPENVAPIPE 399
            |.:.:...|:
Human   559 LEKLLTRFPQ 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12213	NP_001097754.1	CCDC158	<33..>213	CDD:292543	49/197 (25%)
RNF214	NP_001070707.1	zf-RING_2	654..699	CDD:290367

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950		0	Normalized mean entropy	S8005
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950