Protein Alignment aurA and TPK3

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_012755.1
• Gene: TPK3 / 853688
• SGDID: S000001649
• Length: 398
• Species: Saccharomyces cerevisiae
• Alignment Length: 339
• Identity: 120/339 - (35%)
• Similarity: 178/339 - (52%)
• Gaps: 15/339 - (4%)

  Fly    76 NNFQKPMVPSVKKTTSE-FAAPAPVAPIKKPESLSKQKPTAASSESSKELGAASSSAEKEKTKTE 139
            |..:|..:.:..:||.: .....||......|..|...|...:..:|.:|...:|:......|..
Yeast     9 NEIRKLSITAKTETTPDNVGQDIPVNAHSVHEECSSNTPVEINGRNSGKLKEEASAGICLVKKPM 73

  Fly   140 TQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGE-SNVEH--QVRR 201
            .|.:.....:.|::|.|.|.||.|.||.|:|.|...:....|||.|.|..|.: ..|||  ..||
Yeast    74 LQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERR 138

  Fly   202 EIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSA 266
            .:.|.|   ||.|:|::..|.|..:::::::|...|.||:.|:..  :||....:..|...:|.|
Yeast   139 MLSIVS---HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVCLA 198

  Fly   267 LLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQGKPHTK 331
            |.|||.:|||:||:||||:||...|.:||.|||::.:.|: :..|||||.||:.||:|..||:.|
Yeast   199 LEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD-VTYTLCGTPDYIAPEVVSTKPYNK 262

  Fly   332 NVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRL- 395
            :||.||.|||.:|:|.|:.|||:.|..:||:.||..:.|.|......|..|:.||:..:...||
Yeast   263 SVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLG 327

  Fly   396 ----PLDQVMVHPW 405
                ..:.|..|||
Yeast   328 NLQNGSEDVKNHPW 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	105/261 (40%)
TPK3	NP_012755.1	STKc_PKA_like	86..376	CDD:270732	105/262 (40%)