Protein Alignment aurA and aurkb

DIOPT Version :10

• Sequence 1: NP_476749.1
• Gene: aurA / 41446
• FlyBaseID: FBgn0000147
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_997731.2
• Gene: aurkb / 791894
• ZFINID: ZDB-GENE-020419-40
• Length: 320
• Species: Danio rerio
• Alignment Length: 331
• Identity: 168/331 - (50%)
• Similarity: 227/331 - (68%)
• Gaps: 34/331 - (10%)

  Fly    84 PSVKKTTSEFAAPAPVAPIK---KPESLSKQKPTAASSESSKELGAASSSAEKEKTKTETQPQKP 145
            |.|::|.|     |.|.|::   .|::.:...|.....:|:
Zfish     9 PKVQQTPS-----AGVGPLRVEMNPDTHAVSGPGRVPVKSN------------------------ 44

  Fly   146 KKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLR 210
            .|...:::|||||.||:|||||||||||::.:.|:|||||||.|:.:..||||:|||||||||||
Zfish    45 SKVLSIDDFDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLR 109

  Fly   211 HPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDI 275
            ||:|||.|.|||||.|::|||||||:|.::..||.  ...||::::|||::.:..||.|.||:.:
Zfish   110 HPNILRFYNYFHDDTRVFLILEYAPRGEMYKELQR--YGHFDDQRTATYMEEVSDALQYCHEKKV 172

  Fly   276 IHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGV 340
            |||||||||||||::|.|||||||||||.|:..|.|:|||:|||||||::|..|.:.|||||:||
Zfish   173 IHRDIKPENLLLGYRGELKIADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGHSHDEKVDLWSIGV 237

  Fly   341 LCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRLPLDQVMVHPW 405
            ||:|.|||:.||.:.::.||||:|.|||.:.|:.:|:.|..||||||..:|..||||..||.|||
Zfish   238 LCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHSPSMRLPLRSVMEHPW 302

  Fly   406 ILAHTQ 411
            :.|:::
Zfish   303 VKANSR 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurA	NP_476749.1	STKc_Aurora	153..407	CDD:270909	156/253 (62%)
aurkb	NP_997731.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		9/33 (27%)
		STKc_Aurora-B_like	46..315	CDD:271019	158/265 (60%)