Protein Alignment CG14731 and T07G12.3

DIOPT Version :10

• Sequence 1: NP_650130.1
• Gene: CG14731 / 41442
• FlyBaseID: FBgn0037964
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_501945.2
• Gene: T07G12.3 / 188242
• WormBaseID: WBGene00011594
• Length: 623
• Species: Caenorhabditis elegans
• Alignment Length: 685
• Identity: 167/685 - (24%)
• Similarity: 260/685 - (37%)
• Gaps: 198/685 - (28%)

  Fly    47 KPDNKMLFVNSSQCQINSMDPFSPTAMYHMTPMPSSACPMIKLMKPQSIDGMNYLYLIASAKELW 111
            |.::|.|:::||:...|                 ..|.|:             |.|...|.|.:.
 Worm    31 KIESKFLYLDSSRSAHN-----------------ICALPI-------------YDYWDTSIKNVM 65

  Fly   112 KKLGVRRLSDIFCAYKRFVRFNDFVNIYFESTLFRFSK------LRNFTKV-DSGNITLRVW--- 166
            .:....|     ..||.:|::.:.||     :.:|..|      .|.|:.: .|.|:.:..|
 Worm    66 HEYNPAR-----NCYKNYVQWTELVN-----STWRIVKDGANCLARCFSGIGGSKNVKIGPWMKP 120

  Fly   167 -----------CWMD----YGRLVYHDVFIFLPFPNPQKVN----NSAPVKRLSVLILGIDSISH 212
                       ||.|    ||.:  |...|      |:|.:    ..||    :|.|..||:::.
 Worm   121 GHVDCEFLETVCWEDNIEVYGHI--HTQII------PRKASPTKFKDAP----NVFIFTIDAMNT 173

  Fly   213 MHYQR-------YFSRVRDLIEGLPHTELWGYNRVGQNSYPNLIPLLSGQSV--------DEVEA 262
            ...:|       ||.....:|| .|..     |:||:||.||.:||..|:|:        |:||.
 Worm   174 GMAKRSFPKLLSYFKNEFQMIE-FPFV-----NKVGENSRPNGLPLWFGKSIEGGRRVTGDDVEV 232

  Fly   263 ----KSGCYGASGGTNFDRCHLLWHDFQAAGYATIFGED--SRVAGTF-TYVRPGFKKRPTDFYL 320
                ...|     .|..|....::.||:..||||:..||  ..|..:: |.|  ||::.|||...
 Worm   233 DWDWNQYC-----ETYLDNSSHIFKDFKDHGYATMLFEDWEGNVVDSWPTCV--GFEEPPTDHTF 290

  Fly   321 R--SVINEIHMRSTYFARGPLEI---KCSGD--RVYHHVLYDFIYRLLPHMQARMYDRGFFAFFW 378
            |  :.::|.|         .:||   ..||.  |..||.    |..||........||..|::.|
 Worm   291 RPFASVSETH---------GMEITKRHLSGKFCRETHHA----IMELLEQGIEAYKDRPIFSWLW 342

  Fly   379 QTMGVHDYFQYGERADWEYYRIMRALKRRKILERTLVLIVSDHGLRYGPFVDTFQGMRETSLPIM 443
            .....||:.....|.|  .|.:....|...:.:.:.|:.|||||||.|..:.|..|..|...|.:
 Worm   343 LAWVAHDWIDGAARVD--EYLVNYFKKHNNMFDNSFVMFVSDHGLRTGKHMRTEIGAFERDNPFL 405

  Fly   444 VAIYPRSLR-ERFPLAFANLEANAHRLVTTYDLHETLKDVVDLE-----------NLSDERILNR 496
            ....|:..| .:|.: ...|..::.:|.|.:|:..||.|::..:           |:.||:
 Worm   406 SISIPKRFRATKFGI-LETLNFDSKQLQTHFDVRATLLDILKFQPTSKFMDRQQKNIPDEK---- 465

  Fly   497 TLRLRNNHNVSLFLPIPE-ERSCFSARIPLHYCQC--DGY------VKIPWNVRSIQRI-AKLAV 551
                  .|  ||....|: .|:|.:..||..:|.|  |.:      :|.....:.:..: .||..
 Worm   466 ------GH--SLIRKQPDFPRTCATLPIPQQWCICQVDKFEIHNETLKNHLGEKLLNHVHRKLKK 522

  Fly   552 ANINRLLAPYPQCEQLELLNV----EDAYLR--KQHKLNKTIIVRLVTQPGNGHFDATVLSKNET 610
            .|::.:      ||...|..|    |..|:|  :.:|::..     .|.....||:..|....||
 Worm   523 LNVSEI------CETFRLSKVTSLIEYGYVRTMRTYKISVE-----TTISSYAHFETFVTYDIET 576

  Fly   611 SLQ--GPITRTDQYRHQSFCA---REAPIEIYCYC 640
            .:.  ..:||.|.|...:.|.   |::|:   |||
 Worm   577 DIAKFEKVTRLDNYAMTTDCTKPIRQSPL---CYC 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14731	NP_650130.1	DUF229	77..573	CDD:397236	141/579 (24%)
T07G12.3	NP_501945.2	DUF229	67..538	CDD:397236	134/539 (25%)