Protein Alignment CG14731 and R03G8.3

DIOPT Version :10

• Sequence 1: NP_650130.1
• Gene: CG14731 / 41442
• FlyBaseID: FBgn0037964
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_510174.3
• Gene: R03G8.3 / 181437
• WormBaseID: WBGene00010998
• Length: 654
• Species: Caenorhabditis elegans
• Alignment Length: 688
• Identity: 155/688 - (22%)
• Similarity: 276/688 - (40%)
• Gaps: 126/688 - (18%)

  Fly    17 LILMCIILY-VLINFRE-----QVEHKMKEQPPIEGKPDNKMLFVNS-----SQCQINSMDPFSP 70
            |:..|..:| ||:.|..     ..:..:....||.|...:|::...|     .||::...|.:..
 Worm    17 LVTGCFAMYLVLLGFTMFSPLLSPQQYLGLYQPISGNIPSKVVMNKSEVEPWDQCELPQYDIWDD 81

  Fly    71 TAM--YHMTPMPSSACPMIKLMKPQSIDGMNYLYLIASAKELWKKLGVRRLSDIFCAYKRFVRFN 133
            ..:  .:|...|.|.|       .:|.:.:.:|     ....|..  |.:.:.:.|..:...|.:
 Worm    82 EILPYLNMEVNPISNC-------NKSREPLTFL-----NNGSWGV--VNKKTKLICRARCHTRKS 132

  Fly   134 DFVNIYFESTLFRFSKLRNFTKVDSGNITLRV---WCWMDYGRLVY---HDVFIFLPFPNPQ-KV 191
            :           |::.:.|:| ...|.|...|   .| .|..:.||   |...|..|...|. ||
 Worm   133 E-----------RYNVIGNWT-YTPGPINCEVVEAVC-ADGKKDVYGFLHTQVIATPPKQPTVKV 184

  Fly   192 NNSAPVKRLSVLILGIDSISHMHYQRYFSRVRDLIEGLPHTELWGY-NRVGQNSYPNLIPLLSGQ 255
            :.   :|...|.::.:||:|....:|...|....:.......|:.| |:||.||.||...|..|:
 Worm   185 SE---LKNYDVTVIMLDSLSFTQAKRSLLRTISYMTNHMDAVLFPYINKVGDNSRPNGAALWFGK 246

  Fly   256 SVDEVEAK-----------SGCYGASGGTNFDRCHL-------LWHDFQAAGYATIFGEDSRVAG 302
            |:::::..           |..|         .||:       |:.::|..||.|:..|| ...|
 Worm   247 SLEKLDRSLFEEENVPVDWSHAY---------MCHVYKDNETSLFKEYQNYGYKTLMAED-WAEG 301

  Fly   303 TFTYVR-PGFKKRPTDFYLRSVINEI------------HMRSTYFARGPLEIKCSGDRVYHHVLY 354
            |..:.. .||.|.|.|..:|...|.:            |:::..:        |..|   ||.|.
 Worm   302 TLNWPNCKGFDKPPIDHLMRPFQNALERANHGEPLTKSHLKNQKY--------CRED---HHTLL 355

  Fly   355 DFIYRLLPHMQARMY-DRGFFAFFWQTMGVHDYFQYGERADWEYYRIMRALKRRKILERTLVLIV 418
            |::.:.:     ..| |:..|.:.|.::..||.......:|.::::.:  :|.|:.|:.:.|..:
 Worm   356 DYLSQFI-----NAYPDQNKFRWIWASILGHDSENGFPHSDKDFHKFL--IKHREQLDNSFVFFM 413

  Fly   419 SDHGLRYGPFVDTFQGMRETSLPIMVAIYPRSLRERFPLAFANLEANAHRLVTTYDLHETLKDVV 483
            .|||||:|....||.|..:.|.|.:....|::||:...|... :..||.::.|.:|...|:.|::
 Worm   414 GDHGLRFGNVRKTFVGTLDVSNPFLAVSIPKNLRQTTGLLNV-MRENAQKIQTHFDTRATMLDIL 477

  Fly   484 DLENLSDERILNRTLRLRNNHNVSLFLPIPE-ERSCFSARIPLHYCQCDGYVKIPWNVRS----- 542
            ..::.|:...|: .|.:......|.....|: .|:|.:..||:.||.|. :.|...:.:|
 Worm   478 KYQSASNFTDLD-PLIIPGEKGYSYIRTQPDILRNCRNMPIPMQYCICQ-FNKTQVSTKSETAKG 540

  Fly   543 IQRIAKLAVANINRLLAPYPQCEQLELLNVEDAYLRKQHKLNKTIIVRLV---TQPGNGHFDATV 604
            :.....|||.|.........:|.::::.:|. :.|:...|...:::...|   |:|....:.|.|
 Worm   541 VGEAVALAVNNEIEEGKFTDKCVKMKVDHVV-SLLQFDQKFKGSMLYTAVVEMTKPSKAVYKANV 604

  Fly   605 --LSKNETSLQGPITRTDQYRHQSFCAREAPIEIYCYC 640
              |...|..:.|.:.|:::|...::|........||||
 Worm   605 KILENGEVKVLGMVERSNKYGSTAYCIGSEHHRPYCYC 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14731	NP_650130.1	DUF229	77..573	CDD:397236	122/541 (23%)
R03G8.3	NP_510174.3	DUF229	92..570	CDD:397236	122/538 (23%)