Protein Alignment CG14731 and Y73F8A.35

DIOPT Version :10

• Sequence 1: NP_650130.1
• Gene: CG14731 / 41442
• FlyBaseID: FBgn0037964
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001255870.1
• Gene: Y73F8A.35 / 178438
• WormBaseID: WBGene00013539
• Length: 654
• Species: Caenorhabditis elegans
• Alignment Length: 693
• Identity: 161/693 - (23%)
• Similarity: 277/693 - (39%)
• Gaps: 138/693 - (19%)

  Fly    17 LILMCIILYV-LINFREQVEHKMKEQ-----PPIEGK-PDNKMLFVNS---SQCQINSMDPFSPT 71
            ||:.|.|.|: |:.|...|......|     .||.|| .:|..|.|..   .:|.:...:.::..
 Worm    14 LIITCFITYLGLLAFTLLVPAPTSIQYVGVYQPIFGKLEENGSLVVKGDLWDRCDLPDYEIWNDD 78

  Fly    72 AM--YHMTPMPSSACPMIKLMKPQSIDGMNYLYLIASAKELWKKLGVRRLSDIFCAYKRFVRFND 134
            .:  .:|...|.:.|   .:..|.:       |||..:   |..:......|  |..:...|.:|
 Worm    79 ILKYLNMDETPITKC---NIAPPLT-------YLINGS---WNAVNASAGYD--CKTRCHWRKDD 128

  Fly   135 FVNIYFESTLFRFSKLRNFTKVDSGNIT--------LRVWCWMD----YGRLVYHDVFIFLPFPN 187
            ..|.                 :.:.|.|        |...|..|    ||.:  |...|..| |.
 Worm   129 RTNF-----------------IGNWNSTPGPVDCEFLEAICLKDNLKVYGYM--HSQIIPTP-PI 173

  Fly   188 PQKVNNSAPVKRLSVLILGIDSISHMHYQRYFSRVRDLIEGLPHTELWGY-NRVGQNSYPNLIPL 251
            ..||:.| .:::..|.::.:||::|....|...|....:.......::.| |:||:||..|.:||
 Worm   174 TPKVDVS-KLQQYDVTVILLDSLAHAQALRSLPRAISYMTSHMSAVVFPYVNKVGENSRSNGVPL 237

  Fly   252 LSGQSVDEVEAKSGCYGASGGTNFDR------------CH-------LLWHDFQAAGYATIFGED 297
            ..|:|:::::.          :.||.            |:       .::::|:..||.|:..||
 Worm   238 WFGKSLEKLDK----------SLFDEEDVTVDWTHEYMCNEFKDNETSIFNEFRDYGYKTLLAED 292

  Fly   298 SRVAGTFTYVR-PGFKKRPTDFYLRSVINEIHM--RSTYFARGPLEIKCSGD--RVYHHVLYDFI 357
             ...||..:.. .||...|.|.|:|...|.:..  ...:..|..|.   .|:  |.:|:.|.:::
 Worm   293 -WAEGTLNFPNCKGFDNPPIDHYMRPFQNALERPHHGEFITRNHLS---PGNLTREHHNTLLEYL 353

  Fly   358 YRLLPHMQARMYDRGFFAFFWQTMGVHDYFQYGERADWEYYRIMRALKRRKILERTLVLIVSDHG 422
            .:.   |.|...::. |::.|.:...||.......||.::|..:  :|.|:.|:.:.|:::.|||
 Worm   354 SKF---MNAYPNEKK-FSWIWASHLGHDSMNGFSHADNDFYNFL--VKHREKLDNSFVILMGDHG 412

  Fly   423 LRYGPFVDTFQGMRETSLPIMVAIYPRSLRERFPLAFANLEANAHRLVTTYDLHETLKDVVDLE- 486
            .|:|....|..|..|...|.:....|::||:...: .:.::.||.:|.|.||...|:.|::..:
 Worm   413 PRFGANRKTVSGELEVHNPFLGISIPKALRKTTEI-LSLMKGNAKKLQTHYDTRATILDILKYQS 476

  Fly   487 --NLSDERILNRTLRLRNNHNVSLFLPIPE-ERSCFSARIPLHYCQCDGYVKIPWNVRSI----- 543
              |..|..|    |::......|.....|: .|:|.:..||:.||.|    |......||
 Worm   477 TTNFLDTEI----LKIPGEKGFSFIRKQPDTPRNCKTMPIPIQYCLC----KFNRTTESIHSDLA 533

  Fly   544 QRIAKLAVANINRLLAP---YPQCEQLE---LLNVEDAYLRKQHKLNKTIIVRLVTQ---PGNGH 599
            ..:||...|.:|..|..   ..:|.::|   :|:::    |...|...:|:..:|.:   |.|..
 Worm   534 HSMAKALTAAVNTELENGKLQSRCIKMEYSIILSLD----RLDEKFRGSILYTIVVEMKKPSNAW 594

  Fly   600 FDATV--LSKNETSLQGPITRTDQYRHQSFCAREAPIEIYCYC 640
            |.|.:  ||..|..:.|.|.|.::|...:.|.:......||:|
 Worm   595 FKANIKMLSTGELKVLGIIERVNEYGQTAHCIKSEYHRPYCFC 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14731	NP_650130.1	DUF229	77..573	CDD:397236	124/547 (23%)
Y73F8A.35	NP_001255870.1	DUF229	89..557	CDD:397236	121/532 (23%)