Protein Alignment Sbf and sbf1

DIOPT Version :10

• Sequence 1: NP_477401.2
• Gene: Sbf / 41427
• FlyBaseID: FBgn0025802
• Length: 1993
• Species: Drosophila melanogaster
• Sequence 2: XP_012813917.1
• Gene: sbf1 / 100125154
• XenbaseID: XB-GENE-1013544
• Length: 1923
• Species: Xenopus tropicalis
• Alignment Length: 2102
• Identity: 834/2102 - (39%)
• Similarity: 1189/2102 - (56%)
• Gaps: 292/2102 - (13%)

  Fly     1 MSRLADYFVIVGYDSDKEKTASNVGGQPTCGKIVQRFPEKDWPDTPFIEGIEWFCQPLGWSLSYE 65
            |:||||||::||||..|.  .|.:|.    |:|:||||||||.|.||.:|||.||||.||.||.|
 Frog     1 MARLADYFLVVGYDLTKR--GSGIGQ----GRILQRFPEKDWEDNPFPQGIELFCQPSGWQLSTE 59

  Fly    66 KQEPKFFVSVLTDIDANKHYCACLSFHETVAITQTRSVDDEDETIGSSRLLGATPSSMDGITTTS 130
            |:.|.||::|||||.:.:|||:|.:|.|  .:...:|:.|:                .||.....
 Frog    60 KKPPTFFIAVLTDISSERHYCSCFTFWE--ELENIQSLHDQ----------------RDGELEED 106

  Fly   131 TPASITHHSVMYAPKCLVLISRLDCAETFKNCLGTIYTVYIENLAYGLETLIGNILGCIQVPPAG 195
            .|...|  :.:.|||.|||:||||..|.|::.||.|||::.:.|:..||.:|||:|.| .||..|
 Frog   107 APLPST--AQLCAPKTLVLVSRLDHPEVFRDSLGLIYTIHTDGLSVSLENVIGNLLTC-TVPVTG 168

  Fly   196 GPQ-------VR-FSIGAGDKQSLQPPQSSSLPTTGSGVHFLFKQLGIKNVLILLCSVMTENKIL 252
            |.|       || .|:||||:|.:|.|...|||.:...|..||:||||.|||.|.|:.:||:|||
 Frog   169 GSQSDLEQDTVRTISLGAGDRQVIQTPICDSLPISNCSVALLFRQLGITNVLCLFCAALTEHKIL 233

  Fly   253 FLSKCYWHLTDSCRALVALMYPFRYTHVYIPILPAPLTEVLSTPTPFIMGIHSSLQTEITDLLDV 317
            |||..|..||::||||:|:|:|.||:..|:|||||.|.||||||||||:|:::..:.|..:||||
 Frog   234 FLSTSYQRLTEACRALLAIMFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNALFRAETQELLDV 298

  Fly   318 IVVDLDGGLVTIPESLTPPVPILPSPLWEQTQDLLSMILFPNLAQADLAFPTLERPSAI-AKTDA 381
            ::.|||||.||:||.:  .:|.||.||...||:.:|.:|.|:|..||||||    ||:| |.|..
 Frog   299 VIADLDGGTVTVPECV--QIPFLPEPLLHHTQEAISQVLDPSLVIADLAFP----PSSITASTLR 357

  Fly   382 QIDKELRAIFMRLFAQLLQGYRSCLTIIRIHPKPVITFHKAGFLGARDLIESEFLFRVLDSMFFT 446
            ..|.|:||.|:|||||:.||||.||.:|||||:|||.||||.|||.|.|:|.:||.:||:.|.|.
 Frog   358 MQDMEIRASFLRLFAQIFQGYRCCLQLIRIHPEPVIRFHKASFLGQRGLVEDDFLTKVLEGMAFA 422

  Fly   447 TFVNERGPPWRSSDAWDELYSSMNELLKSEAQNRNLVGRTQRFKGYFNFTFPSYFQILTHIQELG 511
            .||.|||.|:|:.|.:|||.:...:.|:.|...:|                     |:.|:::|.
 Frog   423 GFVTERGAPYRALDLFDELVAYEVKKLQYEDTQQN---------------------IIKHVRDLA 466

  Fly   512 RVLYENEGTLAHISYAQKVLRPPEGAFQRIHQPAFPRISSEKVELIIQEGIRK-NGVPQRFHVTR 575
            ..||.||.....:| ..||.||.||::.|.....||.:....::..:.:...| ...|....|.:
 Frog   467 EKLYRNENPYPAVS-MHKVQRPAEGSYMRPQHRPFPMLDESSIQWTLDQAAAKMQHAPPTVRVEK 530

  Fly   576 NQHRIIPMGPRLPEALDVRPNVQ-NSARRLEVLRICVSYIFENRITDARKLLPAVMRTLMHRDAR 639
            .  .::|.||.:....:.....| ||.|||||:|.|:||||||::.:|:||.|||:|.|..|.||
 Frog   531 K--CMVPPGPPIAAIFERNGATQANSNRRLEVVRNCISYIFENKMLEAKKLHPAVLRALKGRAAR 593

  Fly   640 LILCREFFGYVHGNKAVLDHQQFELVVRFMNKALQKSSGIDEYTVAAALLPMSTIFCRKLSTGVV 704
            |.|.:|...:|..|:||||||||:.|||.||..||..:.:||:.:||||||:.|.||||||:|:.
 Frog   594 LCLTQELNLHVQQNRAVLDHQQFDFVVRLMNCCLQDCTPLDEHAIAAALLPLVTAFCRKLSSGIT 658

  Fly   705 QFAYTEIQDHAIWKNLQFWESTFFQDVQGQIKALYLLHRRQNEHQKEANCVLDEVPLEEPTALEI 769
            ||||:.:|:|.:|.|:||||:.|:.|||..|:|||       ...::....:||...||.:|||:
 Frog   659 QFAYSCVQEHVVWTNMQFWEAMFYGDVQNHIRALY-------SSPEDTTTNMDEFEEEERSALEL 716

  Fly   770 TAEQLRKSPNIEEEKKAELAKSEESTLYSQAIHFANRMVSLLIPLDVNVDAASKPKPAFRLEE-- 832
            .|:|.|..|.:..||:.||.:.||||::|||||:||||..||:|||.:.:...:........|
 Frog   717 AADQCRLWPTLPREKQLELIQKEESTVFSQAIHYANRMSYLLLPLDTSKNRMLRGGAGLGDTESV 781

  Fly   833 -NQSVSNSIMGSHSLSEHSDEGFEENNALEIGVTVGKTISRFIDCVCTEGGVTSEHIRNLHDMVP 896
             |..::||:.||.:.|..::.|||::.:.::...|.:.::||:|.||||.||||||::|||.|:|
 Frog   782 TNSFITNSMAGSMAESADTESGFEDSESSDVAHYVVRFVTRFVDKVCTESGVTSEHLKNLHTMIP 846

  Fly   897 GVVHMHIESLEPVYLEAKRHPHVQKPKIQTPCLLPGEDLVTDHLRCFLMPDGREDETQC------ 955
            .:|.||||:|:.|:.|:||.|.:||||:..|.||.||::|.|.||.:|:|||||:.:..
 Frog   847 DIVQMHIETLDAVHRESKRLPPIQKPKLLLPTLLAGEEMVMDGLRVYLLPDGREEASGVSLGGPP 911

  Fly   956 LIPAEGALFLTNYRVIFKGSPCDPLFCEQVIVRTFPIASLLKEKKISVLYLAHLDQTLTEGLQLR 1020
            |:|||||||||:||.||||:|.|.|..||.:||:||||||.|||||:|  ...|||.|.|.||||
 Frog   912 LLPAEGALFLTSYRCIFKGTPVDSLVAEQSVVRSFPIASLTKEKKINV--TVQLDQYLQEALQLR 974

  Fly  1021 SSSFQLIKVAFDPEVTPEQIESFRKILSKARHPFDEFEYFAFQSYGTMLQGVAPLKTKEKYSTLK 1085
            |.:|||:|||||.:|..|..|.|||.|.|.|.|.|....|...: |..:|.....:.|:|..:|.
 Frog   975 SCTFQLLKVAFDEDVPSEASELFRKNLHKLRFPQDVLGTFPLTA-GLTVQHSTQTRAKDKNPSLN 1038

  Fly  1086 --------------GFA----------KKTLLRGAKKAGFKQKQQTKRKLVSDYDY-GSADAQET 1125
                          .|:          .|.|::.|||...:|....::.....:|: ||.::.|.
 Frog  1039 PLHVTDVFQSHVAMSFSLGRFYKDTTLSKNLVKNAKKTIGRQYVTRRKYSPPSWDHRGSQNSLEQ 1103

  Fly  1126 QSIDDELEDGDEFETQNNAMPRLLTTKDVERMRERSYVQDWKRLGFDAES---QRG----FRISN 1183
            ||.|..|.:..|..|...:..:....:.:..:.||:..:|::|:|....|   ||.    ||||.
 Frog  1104 QSDDISLSEEMERNTLTTSTLKAPEKQTIGNVAERACCRDYQRMGLGTLSNSLQRSKNEPFRIST 1168

  Fly  1184 ANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRHANG-ALLIRGGQPNSKSVIG 1247
            .|..||.|.|||.:::.|....|..:..:.||::..|.|:..||.... |:|:|.|..:.|.|:|
 Frog  1169 VNRMYAVCNSYPGLLIVPHSIQDNTLQKISRCYRQNRFPVVCWRSPRSKAVLLRSGGLHGKGVVG 1233

  Fly  1248 MLK--NTTGSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGH--SSSD 1308
            :.|  ||| :...:..|.|.. ||:||..|::|.||:..     :.||.|...:....|  .|.|
 Frog  1234 LFKSPNTT-AVGQSQTDSTSL-EQEKYLQAVVNCMPRFA-----EMSGRNTLSAFPSAHLYDSPD 1291

  Fly  1309 DRQPLTPELSRKHKNNLDISDGNKSSQG-------------GKGGTMKGN--------------- 1345
            .|||....|.::.....:.:.|..|.:|             ||.|:|:|:
 Frog  1292 KRQPKLGSLMKQVIGGKEDNRGGYSVRGIKHPAVRRGYIEQGKWGSMRGSGRLSAYAMNSDVGTR 1356

  Fly  1346 --------------PKNSLAHPFRKMRLYALGEKSQAKSNMNVDFCA--DFIPVDYPDIRQSRPA 1394
                          |..|...| |:..||.:|:|||.| .:..|...  :.:|::..|:||.:.:
 Frog  1357 LAGRELVTHNQNGGPSESALTP-RRAALYIIGDKSQLK-GVKQDPLQQWELVPIELFDVRQVKGS 1419

  Fly  1395 FKKLIRACMPSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSD 1459
            ||||::||:||..::: ..||:.:.:|.|:||.|:..|:|:|..||:|:| ..|||::.||||.|
 Frog  1420 FKKLMKACVPSAPSSD-PSQSYLRTLEDSEWLVQLHKLLQVSVLVVELLD-SGSSVLVGLEDGWD 1482

  Fly  1460 VTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHRSNLKPSH--ANTNIAFAPTFLQFL 1522
            :|.|:.|:.||..|||||:::|||:|||||||:|||||:||.    :|  |:.:..|.|.|||||
 Frog  1483 LTTQVVSLVQLLSDPYYRTIEGFRLLVEKEWLSFGHRFSHRG----AHTAASQSNGFTPVFLQFL 1543

  Fly  1523 DVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGIAAMEDKRGSLNAKHMF 1587
            |.|||:..|||..|||:.:||:|||||.||.||||||.|.:.||.:.|:  :.:::|
 Frog  1544 DCVHQVHLQFPSEFEFSQYYLKFLAYHYVSNRFRTFLLDSDCERIEKGV--LYEEKG-------- 1598

  Fly  1588 GAGGMATNGSDDECSVYPLDIRSQRAPAPLNRIGHSIFDYIERQHNKTPIFYNFLYSGDKSVTLR 1652
                                  .:|:|    ::..|:::.:||.|.|:|:|||:::|.:....||
 Frog  1599 ----------------------DRRSP----QVCRSVWECMERLHKKSPVFYNYMFSPEDGEVLR 1637

  Fly  1653 PQNNVAALDLWCYYTNEELAQGAPYDLEVT-----TVDDEIDLSETKGKRMVITAGYDNMEKCNP 1712
            |.::|..|.:|.|||:|.|::|.|||.|:.     ...:..|.|..:.||.:|...|::..:..|
 Frog  1638 PFSSVWGLRVWDYYTHEALSEGPPYDWELLQGPRHEEPERNDSSAPQTKRKIIWPSYNSPARVEP 1702

  Fly  1713 SAYVCLLSEVKQAETERGHLPQKWLQVWNSLEVPQLEPVARNTSLGNIFVQTHQHKRSTLEIIMK 1777
            .|...||.|:...|.:.|.:|::|...|:.::      .|..|.:      .|:.::|: .::|.
 Frog  1703 DAITRLLEELHSLEMDLGQVPERWKDTWDKIK------AAHRTEV------RHESRKSS-ALLMS 1754

  Fly  1778 GRLAGYQDKYFHPHRFEKHPYTTPTNCNHCTKLLWGPVGYRCMDCGNSYHEKCTEHSMKNCTKYK 1842
            ..::.        ||                                        ||:   ..|.
 Frog  1755 SSVSS--------HR----------------------------------------HSL---GVYL 1768

  Fly  1843 AIDGAVGPPNVNMSQG-DTASIASSAATT-ARTSSHHFYNQFSSNVAENRTHEGHLYKRGALLKG 1905
            ...|.....|:::..| .|:|..|||... ||.|:...|:||::...|||::||.|:||||.:|.
 Frog  1769 QESGVGSTLNLSLESGQSTSSTPSSAGKLGARNSTSTLYSQFNTAERENRSYEGTLFKRGAFMKP 1833

  Fly  1906 WKQRWFVLDSIKHQLRYYDTSEDTAPKGIIELAEVQSVTAAQPAQIGAKGVDEKGFFDLKTSKRI 1970
            ||.||||||..|||||||::..||..||:|:||||:::|.........|.|||:.||||||::|:
 Frog  1834 WKPRWFVLDKTKHQLRYYESRTDTECKGVIDLAEVEAITPGNQTLGAPKNVDERAFFDLKTTRRV 1898

  Fly  1971 YNFYAINANLAQEWIEKLQACL 1992
            |||.|.:|.|||:||:::|:||
 Frog  1899 YNFCATDALLAQQWIDRIQSCL 1920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sbf	NP_477401.2	uDENN	1..91	CDD:214824	52/89 (58%)
		DENN	142..325	CDD:460461	101/190 (53%)
		dDENN	384..452	CDD:129037	42/67 (63%)
		SBF2	584..807	CDD:463536	111/223 (50%)
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396	70/119 (59%)
		PTP-MTMR5-like	1179..1531	CDD:350382	144/402 (36%)
		C1_Sbf-like	1790..1840	CDD:410377	4/49 (8%)
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941	60/105 (57%)
sbf1	XP_012813917.1	uDENN	1..86	CDD:214824	52/90 (58%)
		DENN	117..306	CDD:214823	101/189 (53%)
		dDENN	360..428	CDD:129037	42/67 (63%)
		SBF2	537..754	CDD:463536	111/223 (50%)
		PH-GRAM_MTMR5	883..1001	CDD:275417	70/119 (59%)
		PTP_DSP_cys	1164..1552	CDD:475123	144/402 (36%)
		PH_Sbf1_hMTMR5	1816..1921	CDD:269941	60/105 (57%)