DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG10553

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_651383.1	Gene:	CG10553 / 43064	FlyBaseID:	FBgn0039324	Length:	414	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	164/425 - (38%)
Similarity:	242/425 - (56%)	Gaps:	14/425 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PPNKPEPEVDHSDLVPKWLNQTQFEELLAADVDQFSKIVGFRVKPAMAPGENYATLMLRISIDVE 96
            |..|.|........:|.|:..|.|||||...|..:......|....:|.||||||:||||.:|||
  Fly     3 PQTKDEDVSQKQVTIPDWVKPTVFEELLKRIVKDYKATKSMRANAGVAAGENYATVMLRIELDVE 67

  Fly    97 LTDKSTKLVSFMMKVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFK 161
            ..|.:....:||:|.||.:.|..:::...:.|..|...|.|::|::|:||:..||::||....:.
  Fly    68 KEDNTQTTKAFMLKTPHQSEQYRKVIEKTDIFDVERGMYVEVVPELEQLYRDVGLEVKFGAELYD 132

  Fly   162 LDATKEPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDIF 226
            ::|:.     ..||:.||...||.||:|||.::...|:..|.:.||:|||.|..|:..|||.:.:
  Fly   133 IEASD-----YYVLLEDLRPRGFGNIDRLEGMDQAHTECVLKKFAQWHAASAVRVETKGPYQEKY 192

  Fly   227 VNGVMGNNKEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMK-LGIVDPN 290
            ..|.: .|:|.:.||:...:    ..|:.|:...|..|.|...| :.::|.|.|.:: |....|:
  Fly   193 TKGFL-RNEEIVDAFINRSI----KVFLDNVHLCKGYETYLNDL-RIVSGKTFEIVESLNNPSPD 251

  Fly   291 EFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSHFDFF 355
            ||.||||||.|.||::.:.|:.|:::|..|||.|.||:||...||.||::||..:|.|.|.||:|
  Fly   252 EFIALNHGDGWANNIMSQYNTKGEIQDTYFVDLQVPKWGSVTQDLYYFLLSSTSLDIKTSKFDYF 316

  Fly   356 IRHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSATFDNFMSD 420
            |..|...|||||.:||::...|:||.::..|.||.||....|.::|..|||||...|.||..:.|
  Fly   317 IWFYHSELVKHLKLLGYSKTLPTLRRINDALNKYSGWSFICTATILAYVLLDPVDGADFDKVLGD 381

  Fly   421 SADGVSFRGSLYANKRCQEYIERILPWLDNRGFLE 455
              |..||:.|||.|.|.::::|.:||||.:||.:|
  Fly   382 --DDCSFKNSLYINPRFRKHMEVLLPWLQHRGAME 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	114/292 (39%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG10553	NP_651383.1	EcKinase	52..333	CDD:281023	114/291 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442530
Domainoid	1	1.000	57	1.000	Domainoid score	I17979
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101022at50557
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850