DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG31098

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_733091.1	Gene:	CG31098 / 43057	FlyBaseID:	FBgn0051098	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	113/432 - (26%)
Similarity:	196/432 - (45%)	Gaps:	53/432 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   481 QIPDWLNIDDFKEIILSAEPNFEKILSSTSKLATKP---GD---NFASKLLKVEIEAQLKDNSVK 539
            |.|:||..:..::::   :.:|::...:.::|..|.   ||   .|||::.:.....|.......
  Fly     9 QAPEWLTAEFLQDVL---KEHFKEEQLAVTELIVKSAQVGDQAAGFASEMHRASFNLQRGTAPKG 70

  Fly   540 TFSYILKVH--SDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSK 602
            .||.|:|.|  ....|:.... .||.:||..|...:|..:...:.:|.....:|..: .:.:..:
  Fly    71 KFSVIVKDHPKGQTGAVAHRS-KLFKREILAYKEVLPRIQALLQSIGDQTKIAPTCY-YTTESPE 133

  Fly   603 EYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQTA 667
            .:|:||::|.|||:..:|...::|::...|::|:|:.||.|    .|....||:... .|.|  |
  Fly   134 PFLILEDMQLSGFENFERGRLLNLDYVLPTIEKVAKLHACS----ALIAQDSPEVLE-FFDE--A 191

  Fly   668 PI--------FKGMFVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKINEQAFNVLN 724
            ||        |...|....:...|||:.:.|.:|...||..:.:..:.|.|...:...:.|.|.|
  Fly   192 PISRNPDRRDFLTFFPVNIRCVAEEVAHWKGYEEITEKMFNLAENVLQRALTMFESTGKDFRVFN 256

  Fly   725 HGDAWINNIMFQYESDGRVKETLL-LDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYH 788
            ..|.||||::|...::.:..:.:: ||.|:...|:|..||.||:..|...:::...:.|::|.|.
  Fly   257 LTDLWINNLLFHINNETKEPDDVVTLDFQLAYVGSPTIDLNYFLYGSLNENVRKVHYKYIVREYQ 321

  Fly   789 QNMKEHAKLLNYNGFIPSLKELHAILIQHPIFA--AGTVLTTLSM----------CLNKTTDDFT 841
            :.:::..:.|||.|.||:|||:|..||:..:..  ..|.||.|..          .||..|
  Fly   322 RVLQQTLEKLNYQGHIPTLKEIHIELIKTSLMGVIGATCLTPLIFREGAGFENLEDLNSRT---- 382

  Fly   842 TDSFLGNEENGKSLREAMFSNERYRANIERVMPWINRRGLLD 883
                    |:|...|.....|.:|||.::|.:......|.||
  Fly   383 --------ESGDRFRRENVENPKYRAFLQRTIKEFELSGFLD 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	77/300 (26%)
CG31098	NP_733091.1	EcKinase	50..333	CDD:281023	75/291 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920