DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG11893

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_651375.1	Gene:	CG11893 / 43056	FlyBaseID:	FBgn0039316	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	100/428 - (23%)
Similarity:	184/428 - (42%)	Gaps:	69/428 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PPNKPEPEVDHSDL-VPKWLNQTQFEELLAADVDQFSK-----IVGFRVKPAMAPGENYATLMLR 90
            |.|....:.:..:| .|.|||.....::|..    :.|     :...::.||.|.|::||::|.|
  Fly     2 PENADTEQFNADELEAPAWLNAQFITDVLRT----YEKCPELEVTDLKITPASAQGDHYASVMFR 62

  Fly    91 ISIDVELTDKSTKLVS--FMMKVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDI 153
            .:  .|.|....|...  .:..:|......:.|:|.::.|::|..|||:.||:.|.:.:..|.|.
  Fly    63 TT--AEYTTSKGKFCKPLIIKTMPEQEGHKKDMLSDSHLFSTEINAYTKALPEFERILREAGDDT 125

  Fly   154 K-FAPRAFKLDATKEPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQ 217
            | |.|..:.   :.||:  ..::..||...|:..| |...:|:.:.|...::||::||..   ::
  Fly   126 KLFVPCIYH---SLEPR--QVLIFEDLVPQGYFVI-RDRPINMNEYKNVFSKLAKWHAVS---MK 181

  Fly   218 VHGPYPDI---FVNGVMGNNKEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREKLEK------- 272
            |....|||   |..|:|    |......:.|:.:...:|:..:|:.....:|:...||
  Fly   182 VLNEQPDILKDFKYGLM----EMPSIMSDPMVTTGMDNFLKMMDQIPELTKYKPHFEKIKENYIQ 242

  Fly   273 ALAGLTMEFMKLGIVDPNEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLY 337
            .:..:..|:.|  .|..:.:..:.|||....|::|..|     |:::|||||........:||.|
  Fly   243 RMGDVMQEYRK--NVQSDGYYVMCHGDFHGRNMMFNKN-----EEVMFVDFQICNLCPITIDLSY 300

  Fly   338 FIISSVQIDYKLSHFDFFIRHYQEALVKHLGILGFTGRKPS----LRELHRTLIKYGGWVLFPTI 398
            .:...::.:.:.......|..|...|...|..:|:.|:.|:    .:::||.  |:..:.|..|.
  Fly   301 SVYMLMEPEQRWDLGKDLINFYFSVLEDTLKKVGYKGKMPTNDGLWKQIHRH--KFYDFFLLTTF 363

  Fly   399 SVLPLV-------------LLDP---TQSATFDNFMSD 420
            |  |::             :.||   .:|..:|.::.|
  Fly   364 S--PMIVAVKANTFKIHELIQDPEIRQKSYLYDPYVQD 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	73/304 (24%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG11893	NP_651375.1	EcKinase	52..335	CDD:281023	73/304 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459819
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840