DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG31300

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_651373.2	Gene:	CG31300 / 326132	FlyBaseID:	FBgn0051300	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	422	Identity:	105/422 - (24%)
Similarity:	187/422 - (44%)	Gaps:	32/422 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PKWLNQTQFEELLAADVDQFS-KIVGFRVKPAMAPGENYATLMLRISIDVELTDKSTKLVSFMMK 110
            |.|||:...||:|:|..|... |:|..::.||.|.|::||::|.|.:.:.............:..
  Fly    18 PAWLNRQFIEEILSAYEDSPELKVVDLKITPASAQGDHYASVMFRTTAECTTAKGKFSRPLIIKA 82

  Fly   111 VPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIK-FAPRAFKLDATKEPKVANTV 174
            :|......:.|:|.::.|.:|...|.::||:.|.:.:..|.|.| |.|..:.   :.||:  ..:
  Fly    83 MPEQDGHKKDMLSESHLFETEIGMYCQVLPEFERILRESGDDTKLFVPCIYH---SLEPR--KVM 142

  Fly   175 LMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDIFVNGVMGNNKEAII 239
            :..||...|:..| |...:..|:.|.|..:||::||.....::....:...|..|:.    |...
  Fly   143 IFEDLVPQGYYVI-RDRPVAQEELKTAFAKLAKWHAISMKYIKEQPDFLKEFKYGLF----EMPT 202

  Fly   240 AFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMKLGIVDPNE------FNALNHG 298
            ...:..:.:...||:..||:.....:|:...|| :....|:.::..:.:.:|      |..|.||
  Fly   203 VKTDPFITTGMQSFIEMLDRLPELRKYKPHFEK-IKDKYMQRLQAVMKEYHENRKSDAFYVLCHG 266

  Fly   299 DCWMNNLLFKMN-SSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSHFDFFIRHYQEA 362
            |..:.|::||.| .:|..||.:.||||........:||.|.|...::.:.:.......|.||...
  Fly   267 DFHLRNMMFKNNKGTGAHEDTMLVDFQISNLCPITIDLTYSIYMLMEPEQRREMGKDLINHYLTV 331

  Fly   363 LVKHLGILGFTGRKPSLR----ELHRTLIKYGGWVLFPTISVLPLVLLDPTQSATFDNFMSDSAD 423
            ||..|..:|:.|..|:..    |:|:.  ||..:.|..|.  |||:|...::|...::.:.|.
  Fly   332 LVATLKSIGYPGELPTQAKLWDEIHKN--KYYDFFLLSTF--LPLILAIKSKSFKVNDLIQDP-- 390

  Fly   424 GVSFRGSLYANKRCQEYIERILPWLDNRGFLE 455
              ..|...|......:.:.::||..:..|:.:
  Fly   391 --ETRQKTYFLDTYVKDVSKLLPKFEQLGYFK 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	71/299 (24%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG31300	NP_651373.2	EcKinase	52..341	CDD:281023	71/299 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459817
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840