DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG31102

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001262951.1	Gene:	CG31102 / 326118	FlyBaseID:	FBgn0051102	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	143/434 - (32%)
Similarity:	214/434 - (49%)	Gaps:	26/434 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PPNKPEPEVDHSDLVPKWLNQTQFEELLAADVDQFSKIVGFRVKPAMAPGENYATLMLRISIDVE 96
            |.|..:........:|.|:|:..|:.||..:..:|.:|:...:.||..|||.|.:|::||.||:|
  Fly     2 PDNSNKFSASSDVRIPAWINEAYFKRLLKREFREFRRILNLSIIPATPPGETYTSLLMRIVIDIE 66

  Fly    97 LTDKSTKLVSFMMKVPHDTPQME-QMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAF 160
            |.|..::..|:::|...|..|.. ..::..|.|..|...|..|:|.:|:||:..||.:||||
  Fly    67 LKDGFSQQKSYIVKTMLDDAQGNGGFVNTLNIFPKEKMMYETIIPNLEQLYEEAGLSVKFAP--- 128

  Fly   161 KLDATKEPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDI 225
            |....::.|....::..||....::|||||:..::......|.:||:||||||...|..||:||.
  Fly   129 KCHHAEDIKGRICLVQEDLQTKKYRNINRLKGFDMAHMHRVLEKLAEFHAAGAVWRQRKGPFPDD 193

  Fly   226 FVNGVMGNNKEAIIAFMEGMLASFRTSFMANLDKFKNG---------EEYREKLEKALAGLTMEF 281
            |....:..|.:.            ..|:.|.|..:|..         |:|..::..| ......:
  Fly   194 FQRIYLPANYQK------------SKSYQARLQSYKTAIASWGLADHEQYVSRIPTA-DQFVQSY 245

  Fly   282 MKLGIVDPNEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQID 346
            ......:|.||..|||||.|.:|::.....:||:..:.|||||..|:||||.||...||.|.:..
  Fly   246 ASCFNNNPQEFKVLNHGDFWSSNIMLSYTQTGDINQVRFVDFQLCKWGSPAQDLWELIICSARHS 310

  Fly   347 YKLSHFDFFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQS 411
            .::.:||:|||.|...||:.|.||.::.|.|.|||||.::||||.|..|.|.:.|..:||.|...
  Fly   311 IRIQYFDYFIRIYHTHLVRCLKILKYSERIPMLRELHMSMIKYGFWGYFTTFTHLVFILLPPDTE 375

  Fly   412 ATFDNFMSDSADGVSFRGSLYANKRCQEYIERILPWLDNRGFLE 455
            |:.........:|..||..:|.|.........|.|:|..||.|:
  Fly   376 ASLVKLTQPGEEGDRFRSKVYTNPLYVRSALSIFPFLLRRGILD 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	101/301 (34%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG31102	NP_001262951.1	EcKinase	50..336	CDD:281023	101/301 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442532
Domainoid	1	1.000	207	1.000	Domainoid score	I6156
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850