DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and E02C12.9

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001343650.1	Gene:	E02C12.9 / 183988	WormBaseID:	WBGene00017094	Length:	352	Species:	Caenorhabditis elegans

Alignment Length:	348	Identity:	69/348 - (19%)
Similarity:	126/348 - (36%)	Gaps:	119/348 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 DWLNIDDFKEIILSAEPNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVKTFSYILKVH 548
            ||::::                          .|.|..||.....::..:.:|.:|.|..:
Worm    59 DWVDVE--------------------------KGKNVPSKFAVYGLKKFIDENDMKGFLIV---- 93

  Fly   549 SDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSKEYLLLENLQPS 613
                     ||.....::.:|.: :||.|......|:. |||....:|| |..|::       ..
Worm    94 ---------DFVSNAHDVGMYLS-IPADELIPLVRGIS-TFSALGEKLS-DNEKKF-------AG 139

  Fly   614 GFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQTAPIFKGMFVNTK 678
            |...::||                               :|..:|:....:.    |:||:...:
Worm   140 GSDFLERM-------------------------------FSQLFNSSSLQKH----FQGMYSVFE 169

  Fly   679 KSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKINE-QAF-NVLNHGDAWINNIMFQYESDG 741
            |   |:..:.||:.|......::|..|       .||:| ..| :||||||.|.:|::...|::|
Worm   170 K---EKYYQVDGLIETFVVYQKLLKKY-------TKISELLGFKSVLNHGDLWQSNMIHSMENNG 224

  Fly   742 RVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYH--------------QNMK 792
            ::|...::|.|.|....|..|....|:.....:.:.::...|:..||              :.::
Worm   225 KLKLEAIIDWQSTVILPPGLDTAELIVGCLSAEDRREKGHDLLLLYHKTFINVFGSEVFSFEELQ 289

  Fly   793 EHAKLLNYNGFIPSLKELHAILI 815
            :     :||.:.|    :.||||
Worm   290 D-----SYNLYFP----MAAILI 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	60/299 (20%)
E02C12.9	NP_001343650.1	PKc_like	3..343	CDD:389743	69/348 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810