DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6830 and T16G1.7

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_506233.1	Gene:	T16G1.7 / 179774	WormBaseID:	WBGene00011801	Length:	436	Species:	Caenorhabditis elegans

Alignment Length:	364	Identity:	77/364 - (21%)
Similarity:	144/364 - (39%)	Gaps:	94/364 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   486 LNIDDFKEIILSAEPNFEKILSSTSK-LATKPGDNFASKLLKVEIEAQLKDNSVKTFSYILKVHS 549
            :.:||.:::| ..:.|.|..|...:| .....|:.|.|:::.||.|..:.|..:.. .:|||:.|
Worm    22 VQLDDVQDVI-GEQMNTEARLGKNTKYTVVGDGNGFMSRVILVEPEWTVPDEHLPE-KFILKITS 84

  Fly   550 ---------------------DNDAINFSDF-----NLFPKEIEVYSTYVPAFERFYKDVGLPVT 588
                                 :.:|..::.|     .|..:|:.:|.    ..|::.|:   ...
Worm    85 CLHVHGLVEKMKGKSPGAFPAEQEAALWAIFENEAQQLHNREVNLYK----ITEKWNKN---ETM 142

  Fly   589 FSPKSFRLSK-DVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKC---------TLKKLAQWHAAS 643
            .|||.:...| |.       || :..|...::.:..:.:.|..|         .|:.||...|.|
Worm   143 LSPKIYFYKKFDA-------EN-KTKGILGMEFVSDVTIRHLYCNAKPYELHPVLRSLATLQAGS 199

  Fly   644 L-------------KYKELNGPYSPKYNNGIFTEQTAPIFKGMF---VNTKKSFIEEVSKFD--- 689
            |             .:|::.|....:.......|||..|.....   .||.::|..||..|:
Worm   200 LHLTEDEINSISGFDFKQMMGAMMNEEGMKNIYEQTREINPERLTEKTNTVEAFGLEVVNFELSC 264

  Fly   690 GVDEYLHKMPEILDTYVDRILEDAKINEQAFNVLNHGDAWINNIMFQYESDGRVKETLLLDHQVT 754
            .:::|:.         ::|            :||.|||.|..||:::.|:||:...:.::|:|:.
Worm   265 NLNKYVG---------IER------------DVLVHGDLWAANILWKEENDGKFSVSKVIDYQLI 308

  Fly   755 KYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKE 793
            ..||||:||....:|:.....:...::.|:..:::...|
Worm   309 HMGNPAEDLVRVFLSTLSGADRQAHWERLLEQFYEYFLE 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	70/333 (21%)
T16G1.7	NP_506233.1	DUF1679	10..423	CDD:369592	77/364 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810