Protein Alignment Mrp4 and ABCC12

DIOPT Version :10

• Sequence 1: NP_650086.2
• Gene: Mrp4 / 41387
• FlyBaseID: FBgn0263316
• Length: 1316
• Species: Drosophila melanogaster
• Sequence 2: NP_001319111.1
• Gene: ABCC12 / 839921
• AraportID: AT1G30410
• Length: 1498
• Species: Arabidopsis thaliana
• Alignment Length: 1317
• Identity: 465/1317 - (35%)
• Similarity: 719/1317 - (54%)
• Gaps: 106/1317 - (8%)

  Fly    13 PRERSSPLSSLMFCFALPVLFKGRKKTLEQKDLYRALKEHKSDSLGDRLCAAWDEQVAKNETPRL 77
            |...:|..|.:.|.:..|::..|.:|.:.:||:::..|..::::|..|....|.|: ::...|.|
plant   228 PERHASIFSRIYFGWITPLMQLGYRKPITEKDVWQLDKWDQTETLIKRFQRCWTEE-SRRPKPWL 291

  Fly    78 GRALTKVFGFHLFITGVFLLAQ--EFLTKVTQPICLIGVMAYFAGNDPDRSKAQLWAAGLIAGSV 140
            .|||....|...::.|:|.:.:  ..|::...|:.|..::......||      .|...:.|..:
plant   292 LRALNNSLGGRFWLAGIFKVTRIGNDLSQFVGPVILSHLLRSMQEGDP------AWVGYVYAFII 350

  Fly   141 F-SVCIG----HPYMLGLLHLGMKMRIALSSLIYRKALRLSRTALGDTTVGQVVNLLSNDVGRFD 200
            | .|.:|    ..|...:..:|.::|..|.:.|:.|:|||:..|..:...|:|.|:::.|.....
plant   351 FVGVTLGVLCEAQYFQNVWRVGFRLRSTLVAAIFHKSLRLTHEARKNFASGKVTNMITTDANALQ 415

  Fly   201 LVLINVHYLWIAPLELIAVTYLMYLEIGISSMFGVAIMLLFLPFQSYLGKRTSVLRLRTALRTDE 265
            .:...:|.||.||..:|....|:|.::|::|:||..|:.|.:|.|:.:..:...|.......||:
plant   416 QISQQLHGLWSAPFRIIVSMILLYQQLGVASLFGSLILFLLIPLQTLIISKMRKLTKEGLQWTDK 480

  Fly   266 RVRMMNEIISGIQVIKMYAWEKPFGKVVEMTRFNEMLCIKQVNYIRGILISFAMFLSR----IFT 326
            ||.:.|||:|.:..:|.|||||.|...::..|..|:...::..    :|.:|..|:..    :.|
plant   481 RVGITNEILSSMDTVKCYAWEKSFESRIQGIRNEELSWFRKAQ----LLSAFNSFILNSIPVVVT 541

  Fly   327 SSSLIAFVLLGNILNAEKAFFVTAYYNILRRSVTMFFPQGISEFAELLVSVRRLEAFMHRPETKV 391
            ..|...|||||..|...:||...:.:.:||..:.| .|..:|:.....||::|:|..:...|..:
plant   542 VVSFGVFVLLGGDLTPARAFTSLSLFAVLRFPLNM-LPNLLSQVVNANVSLQRIEELLLSEERIL 605

  Fly   392 RDKSKVKNANQKAESPNGDSPKGNGIPENLIEFSQFQARWESHSLEPTLEDINLQLGRRKLVAVI 456
                        |::|    |...|.|...|:...|.  |:|.:.:|||.||||::....|||::
plant   606 ------------AQNP----PLQPGTPAISIKNGYFS--WDSKTTKPTLSDINLEIPVGTLVAIV 652

  Fly   457 GPVGAGKSSLIQAILGELP-GESGTLRINGSYSYAAQEPWLFTGTVRQNILFGLDWDKHRYRTVV 520
            |..|.||:|||.|:||||. .|:.::.|.||.:|..|..|:|..|||:|||||.|::..||...:
plant   653 GGTGEGKTSLISAMLGELSHAETTSVVIRGSVAYVPQVSWIFNATVRENILFGSDFESERYWRAI 717

  Fly   521 KKCALERDFELLPFGDKTIVGERGASLSGGQKARISLARAVYRRADIYLLDDPLSAVDTHVGRHL 585
            ...||:.|.:|||..|.|.:||||.::|||||.|:|:|||||..:|:|:.||||||:|.||...:
plant   718 DATALQHDLDLLPGRDLTEIGERGVNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVAHQV 782

  Fly   586 FDQCMRGYLRSELVILVTHQLQFLEQADLIVIMDKGRISAMGTYSSMKRSGLDFAQLLTAPNKDA 650
            ||.||:..||.:..:|||:||.||...|.|:::.:|.|...||:..:.:||:.|.:|:    ::|
plant   783 FDSCMKDELRGKTRVLVTNQLHFLPLMDKIILVSEGMIKEEGTFVELSKSGILFKKLM----ENA 843

  Fly   651 EDLDEIDGAGGDGLDLLNV-PSLSRRGSKNSKPSTRNNSFTSLSSMAESMAQEASLQMQETRVEG 714
            ..:|.......:..::|.: |::           |.:.|..:|.|..:...:.:.|..||.|..|
plant   844 GKMDATQEVNTNDENILKLGPTV-----------TVDVSERNLGSTKQGKRRRSVLIKQEERETG 897

  Fly   715 KIG---LGLYKEYLTSGSSWFMIFFMVFLCLATQILCSAADYFLSYWVDKNVDGQTDINTDPQDM 776
            .|.   |..|||.:  |..| ::..::...|||::|..::..:||.|.|::    |..|..|.
plant   898 IISWNVLMRYKEAV--GGLW-VVMILLACYLATEVLRVSSSTWLSIWTDQS----TSKNYSPG-- 953

  Fly   777 YY---FAALNVAVVVFTIVRTMLFYKMAMRSSTQLHNAMYQGITRAAMYFFNTNPSGRILNRFSK 838
            :|   :|.|....|..|...:......::.::.:||:||...|.||.|.||:|||:||::|||||
plant   954 FYIVVYALLGFGQVAVTFTNSFWLITSSLHAARRLHDAMLSSILRAPMLFFHTNPTGRVINRFSK 1018

  Fly   839 DLGQLDEVLPSVMLDVVQLFLTLLGIIVVICITNPYYLILTLALAIIFYYIREFYLKTSRDVKRL 903
            |:|.:|..:.::|...:.....||....:|...:...|...:.|.|:||....:|..|||:|:||
plant  1019 DIGDIDRNVANLMNMFMNQLWQLLSTFALIGTVSTISLWAIMPLLILFYAAYLYYQSTSREVRRL 1083

  Fly   904 EAVARSPIYSHLSATITGLPTIRALGAQKELIAEFDNLQDLHSSGY-----YTFLAT--NRAFGY 961
            ::|.|||||:.....:.||.:|||..|       :|.:..::....     :|...|  ||....
plant  1084 DSVTRSPIYAQFGEALNGLSSIRAYKA-------YDRMAKINGKSMDNNIRFTLANTSSNRWLTI 1141

  Fly   962 YLDCFCTLYIVIIILNYFI---------NPPQSPGEVGLAITQAMGMTGMVQWAMRQSAELENTM 1017
            .|:   ||..|:|.|....         |.......:||.::..:.:|.::...:||::..||::
plant  1142 RLE---TLGGVMIWLTATFAVLQNGNTNNQAGFASTMGLLLSYTLNITSLLSGVLRQASRAENSL 1203

  Fly  1018 TAVERVVEYDEIEPEGEFDSREGKKPSPSWPEKGEIIAEDLCLRYFPD-PQAKYVLKALNFRIRP 1081
            .:||||..|.:: |....|..|..:|...||..|.|..||:.|||.|. |.   ||..|.|.:.|
plant  1204 NSVERVGNYIDL-PSEATDIIENNRPVCGWPSGGSIKFEDVHLRYRPGLPP---VLHGLTFFVSP 1264

  Fly  1082 CEKVGIVGRTGAGKSSLINALFRL-SYNEGIITIDERDTADMGLFDLRSKISIIPQEPVLFSGSM 1145
            .||||:||||||||||::|||||: ...:|.|.||:.|.|..||.|:|..:|||||.||||||::
plant  1265 SEKVGVVGRTGAGKSSMLNALFRIVEVEKGRIMIDDCDVAKFGLTDVRRVLSIIPQSPVLFSGTV 1329

  Fly  1146 RYNLDPFEEYNDAKLWDALEEVKLKPLISELPNGLQSKISEGGSNFSVGQRQLVCLARAILRENR 1210
            |:|:|||.|:|||.||:||....:|.:||..|.||.:::.|||.|||||||||:.||||:||.::
plant  1330 RFNIDPFSEHNDAGLWEALHRAHIKDVISRNPFGLDAEVCEGGENFSVGQRQLLSLARALLRRSK 1394

  Fly  1211 VLVMDEATANVDPQTDALIQATIRSKFRDCTVLTIAHRLNTIMDSDRVLVMDAGHLVEFGSPYEL 1275
            :||:|||||:||.:||:|||.|||.:|:.||:|.||||||||:|.|::||:.:|.::|:.||.||
plant  1395 ILVLDEATASVDVRTDSLIQRTIREEFKSCTMLVIAHRLNTIIDCDKILVLSSGQVLEYDSPQEL 1459

  Fly  1276 LTSSESKIFHGMVMETG 1292
            | |.::..|..||..||
plant  1460 L-SRDTSAFFRMVHSTG 1475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrp4	NP_650086.2	MRP_assoc_pro	13..1292	CDD:188098	463/1315 (35%)
ABCC12	NP_001319111.1	PLN03232	1..1498	CDD:215640	465/1317 (35%)