Protein Alignment Mrp4 and CG7627

DIOPT Version :10

• Sequence 1: NP_650086.2
• Gene: Mrp4 / 41387
• FlyBaseID: FBgn0263316
• Length: 1316
• Species: Drosophila melanogaster
• Sequence 2: NP_609215.3
• Gene: CG7627 / 34148
• FlyBaseID: FBgn0032026
• Length: 1355
• Species: Drosophila melanogaster
• Alignment Length: 1359
• Identity: 816/1359 - (60%)
• Similarity: 1025/1359 - (75%)
• Gaps: 68/1359 - (5%)

  Fly     1 MQSMKADELPENPRERSSPLSSLMFCFALPVLFKGRKKTLEQKDLYRALKEHKSDSLGDRLCAAW 65
            |||:|..:|||||||..:.:|:..|.:.:|...||||:||:.||||||||||||::||::|||:|
  Fly     1 MQSLKTADLPENPREHCNFISAACFWYTMPTFIKGRKRTLDTKDLYRALKEHKSETLGNKLCASW 65

  Fly    66 DEQVAKNE-TPRLGRALTKVFGFHLFITGVFLLAQEFLTKVTQPICLIGVMAYFAGNDPDRSKAQ 129
            :.::.|.: .|.|.|||.:|||::..:.|:.|...|...:..|||.|:.::||:.........|.
  Fly    66 ELELEKTKGKPNLLRALLRVFGWYFALLGLVLFLLELGLRTLQPIFLLKLIAYYTHGSESIESAY 130

  Fly   130 LWAAGLIAGSVFSVCIGHPYMLGLLHLGMKMRIALSSLIYRKALRLSRTALGDTTVGQVVNLLSN 194
            .:|||:|..|..:|.|.||||||.:|:|:|||:.:.|:|||||||||::||||||.|.||||:||
  Fly   131 YYAAGVILCSALNVIIMHPYMLGTMHVGLKMRVGMCSMIYRKALRLSKSALGDTTAGHVVNLMSN 195

  Fly   195 DVGRFDLVLINVHYLWIAPLELIAVTYLMYLEIGISSMFGVAIMLLFLPFQSYLGKRTSVLRLRT 259
            ||||.||..|.|||||:.|||.:.:|||||.||||:::||||.||||:|.|:|||||||||||||
  Fly   196 DVGRLDLATIFVHYLWVGPLETLFITYLMYREIGIAAVFGVAFMLLFIPLQAYLGKRTSVLRLRT 260

  Fly   260 ALRTDERVRMMNEIISGIQVIKMYAWEKPFGKVVEMTRFNEMLCIKQVNYIRGILISFAMFLSRI 324
            |||||||||||||||||||||||||||.||..:|...|..|:..|:.|:||||||:||.:||:|:
  Fly   261 ALRTDERVRMMNEIISGIQVIKMYAWELPFEHMVAFARKKEINAIRHVSYIRGILLSFIIFLTRV 325

  Fly   325 FTSSSLIAFVLLGNILNAEKAFFVTAYYNILRRSVTMFFPQGISEFAELLVSVRRLEAFMHRPET 389
            ....||:.:||||..|..|.||.:||||||||.::|:|||||||:.||.|||::|::.:|...||
  Fly   326 SIFLSLVGYVLLGTFLTPEVAFLITAYYNILRTTMTVFFPQGISQMAETLVSIKRVQKYMQSDET 390

  Fly   390 KVRDKS-----KVKNANQKAESPNGDSPKGNG-----------IPENL------IEFSQFQARWE 432
            .|.|.|     ..:.:||:....:||..:...           :.||.      |..|...|:|:
  Fly   391 NVMDMSVDLTEDFQGSNQETVHADGDEERDEAEDKLLGPPIATVNENAKLSEAGISISGLMAKWD 455

  Fly   433 SHSLEPTLEDINLQLGRRKLVAVIGPVGAGKSSLIQAILGELPGESGTLRINGSYSYAAQEPWLF 497
            .:|.:.:|..:||::....::.::|..|:||||||||||||||.|||.:::|||.|||:||||||
  Fly   456 VNSPDYSLNGVNLRVQPGTMLGIVGRTGSGKSSLIQAILGELPAESGEIKVNGSMSYASQEPWLF 520

  Fly   498 TGTVRQNILFGLDWDKHRYRTVVKKCALERDFELLPFGDKTIVGERGASLSGGQKARISLARAVY 562
            :||||||||||...|:.||..||||||||||||||||.|||||||||||||||||||||||||||
  Fly   521 SGTVRQNILFGQPMDRRRYAKVVKKCALERDFELLPFKDKTIVGERGASLSGGQKARISLARAVY 585

  Fly   563 RRADIYLLDDPLSAVDTHVGRHLFDQCMRGYLRSELVILVTHQLQFLEQADLIVIMDKGRISAMG 627
            |...|||||||||||||||.||||:||||||||..:|||.|||||||:.||.||||||||:||:|
  Fly   586 RETSIYLLDDPLSAVDTHVARHLFEQCMRGYLRERIVILATHQLQFLQHADQIVIMDKGRVSAVG 650

  Fly   628 TYSSMKRSGLDFAQLLTAPNKDAEDLDEIDGAGGDGLDLLNVPSLSRRGS-KNSKPSTRNNSFTS 691
            ||.|::.||||||.:|..|.:|.:..:.               |.||.|| .:|....|.||..|
  Fly   651 TYESLRESGLDFASMLADPERDEQSEER---------------SRSRSGSYTHSHSDQRRNSEQS 700

  Fly   692 LSSMAESMAQEASLQM---QETRVEGKIGLGLYKEYLTSGSSWFMIFFMVFLCLATQILCSAADY 753
            |.|||:|...:...:.   ||.:..|:|||.||.:|..:|..:|..|.|:..|:.:|.|.|..||
  Fly   701 LLSMADSCMDDLEAEQANNQERQEAGQIGLRLYSKYFKAGGGFFAFFVMMGFCVLSQGLASLGDY 765

  Fly   754 FLSYWVDK--NVDGQTDIN-------TDPQ-----------------DMYYFAALNVAVVVFTIV 792
            ||||||.|  ||..:.|.|       .:|:                 |.|.|..:.|..::.|:.
  Fly   766 FLSYWVTKKGNVAYRADNNDTTRSEELEPRLSTWLRDIGLSVDAEMLDTYIFTVITVLTILVTVA 830

  Fly   793 RTMLFYKMAMRSSTQLHNAMYQGITRAAMYFFNTNPSGRILNRFSKDLGQLDEVLPSVMLDVVQL 857
            |:.||:.:||::|.:|||:|::|||||||||||||||||||||||||:||:||:||:||:||:|:
  Fly   831 RSFLFFNLAMKASIRLHNSMFRGITRAAMYFFNTNPSGRILNRFSKDMGQVDEILPAVMMDVIQI 895

  Fly   858 FLTLLGIIVVICITNPYYLILTLALAIIFYYIREFYLKTSRDVKRLEAVARSPIYSHLSATITGL 922
            ||.|.||::||.:.||.:||.|:.|.||||.:|.|||||||||||:||:.|||:||||:|::|||
  Fly   896 FLALAGIVIVIAVVNPLFLIPTVVLGIIFYQLRTFYLKTSRDVKRMEAITRSPVYSHLAASLTGL 960

  Fly   923 PTIRALGAQKELIAEFDNLQDLHSSGYYTFLATNRAFGYYLDCFCTLYIVIIILNYFINPPQSPG 987
            .||||.|||:.|.|||||.||:|||.:|.|::|:|||||:|||||.:||.||.|::||.||.:.|
  Fly   961 STIRAFGAQRVLEAEFDNYQDMHSSAFYMFISTSRAFGYWLDCFCVIYIAIITLSFFIFPPANGG 1025

  Fly   988 EVGLAITQAMGMTGMVQWAMRQSAELENTMTAVERVVEYDEIEPEGEFDSREGKKPSPSWPEKGE 1052
            :|||||||||||||||||.||||||||||||||||||||::|||||..::...|||..||||:|:
  Fly  1026 DVGLAITQAMGMTGMVQWGMRQSAELENTMTAVERVVEYEDIEPEGALEAPADKKPPKSWPEQGK 1090

  Fly  1053 IIAEDLCLRYFPDPQAKYVLKALNFRIRPCEKVGIVGRTGAGKSSLINALFRLSYNEGIITIDER 1117
            |:.::|.|||.|||:::.|||:|:|.|:|.||||||||||||||||||||||||||:|.:.||:|
  Fly  1091 IVFDELSLRYTPDPKSENVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRLSYNDGSVLIDKR 1155

  Fly  1118 DTADMGLFDLRSKISIIPQEPVLFSGSMRYNLDPFEEYNDAKLWDALEEVKLKPLISELPNGLQS 1182
            ||::|||.||||||||||||||||||:||||||||:||:|.|||.:|||||||.::::||:||||
  Fly  1156 DTSEMGLHDLRSKISIIPQEPVLFSGTMRYNLDPFDEYSDDKLWRSLEEVKLKEVVADLPSGLQS 1220

  Fly  1183 KISEGGSNFSVGQRQLVCLARAILRENRVLVMDEATANVDPQTDALIQATIRSKFRDCTVLTIAH 1247
            ||:|||:|||||||||||||||||||||:|||||||||||||||.|||.|||:||::||||||||
  Fly  1221 KITEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQTTIRNKFKECTVLTIAH 1285

  Fly  1248 RLNTIMDSDRVLVMDAGHLVEFGSPYELLTSSESKIFHGMVMETGQNTFDSLLKVAEKA 1306
            ||:||||||:|||||||..||||:||||||.::||:|||||.:||..|::||||:|:||
  Fly  1286 RLHTIMDSDKVLVMDAGRAVEFGTPYELLTLADSKVFHGMVKQTGHATYESLLKIAQKA 1344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrp4	NP_650086.2	MRP_assoc_pro	13..1292	CDD:188098	798/1331 (60%)
CG7627	NP_609215.3	PLN03130	13..1348	CDD:215595	808/1347 (60%)