Protein Alignment Mrp4 and CG31793

DIOPT Version :10

• Sequence 1: NP_650086.2
• Gene: Mrp4 / 41387
• FlyBaseID: FBgn0263316
• Length: 1316
• Species: Drosophila melanogaster
• Sequence 2: NP_609930.4
• Gene: CG31793 / 326161
• FlyBaseID: FBgn0051793
• Length: 1307
• Species: Drosophila melanogaster
• Alignment Length: 1322
• Identity: 822/1322 - (62%)
• Similarity: 1028/1322 - (77%)
• Gaps: 43/1322 - (3%)

  Fly     4 MKADELPENPRERSSPLSSLMFCFALPVLFKGRKKTLEQKDLYRALKEHKSDSLGDRLCAAWDEQ 68
            |:|.:||.||||.:..|||||||||||:||||||:||:..|||:.|.||::.||||.....|:::
  Fly     1 MQASKLPPNPRESAGILSSLMFCFALPILFKGRKQTLQPTDLYKTLNEHEAASLGDEFFQGWEDE 65

  Fly    69 VAK-------NETPRLGRALTKVFGFHLFITGVFLLAQEFLTKVTQPICLIGVMAYFAGNDPDRS 126
            ||:       ...|.:.|.:.:|||:.|.::|:.:.|.|..|:.|.|:.|.|:::.|:.:....|
  Fly    66 VARCRRKGDSGRKPSVLRVIGRVFGWRLIMSGITIAALELGTRATVPLLLAGLISEFSEHGNGHS 130

  Fly   127 -KAQLWAAGLIAGSVFSVCIGHPYMLGLLHLGMKMRIALSSLIYRKALRLSRTALGDTTVGQVVN 190
             .||::|..|||..:.||.:.||||:|::||.||||:|:||.|||||||||||:||.||.|||||
  Fly   131 YNAQIYAVLLIACILASVLLTHPYMMGMMHLAMKMRVAVSSAIYRKALRLSRTSLGGTTTGQVVN 195

  Fly   191 LLSNDVGRFDLVLINVHYLWIAPLELIAVTYLMYLEIGISSMFGVAIMLLFLPFQSYLGKRTSVL 255
            |||||:.|||..||:.|:||:.||||:..:|.:|.:||::|.:|::|::|:||.|:||.:.||.|
  Fly   196 LLSNDLNRFDRCLIHFHFLWLGPLELLIASYFLYEQIGMASFYGISILVLYLPLQTYLSRVTSKL 260

  Fly   256 RLRTALRTDERVRMMNEIISGIQVIKMYAWEKPFGKVVEMTRFNEMLCIKQVNYIRGILISFAMF 320
            ||:||||||:||||||||||||||||||.||:||||::...|.:||..|:|:|.:||||:||.:.
  Fly   261 RLQTALRTDQRVRMMNEIISGIQVIKMYTWERPFGKLIGQMRRSEMSSIRQMNLLRGILLSFEIT 325

  Fly   321 LSRIFTSSSLIAFVLLGNILNAEKAFFVTAYYNILRRSVTMFFPQGISEFAELLVSVRRLEAFMH 385
            |.||....||:.|||.|..|.||:||.|||:||||||:|:.|||.|:|:|||||||:||:..||.
  Fly   326 LGRIAIFVSLLGFVLGGGELTAERAFCVTAFYNILRRTVSKFFPSGMSQFAELLVSMRRITNFMM 390

  Fly   386 RPETKVRDKSKVKNANQKAES--------PNGDSPKGNG-IPENLIEFSQFQARW--ESHSLEPT 439
            |.|..|.|.|  :..::|||.        .....|.|.| .|:.|:|....:|||  |.|.|  .
  Fly   391 REEANVIDMS--ERRDEKAEEEQHLLKEVEKRSYPVGIGKEPDTLVEIKALRARWGQEQHDL--V 451

  Fly   440 LEDINLQLGRRKLVAVIGPVGAGKSSLIQAILGELPGESGTLRINGSYSYAAQEPWLFTGTVRQN 504
            |.::|:.|.|.:|||||||||:||||||||||||||.|||:::::|.||||:||||||..:||.|
  Fly   452 LNNVNMSLRRGQLVAVIGPVGSGKSSLIQAILGELPPESGSVQVSGKYSYASQEPWLFNASVRDN 516

  Fly   505 ILFGLDWDKHRYRTVVKKCALERDFELLPFGDKTIVGERGASLSGGQKARISLARAVYRRADIYL 569
            |||||..||.|||||:|:||||||.||| .||.||||||||||||||:|||.||||||||||:||
  Fly   517 ILFGLPMDKQRYRTVLKRCALERDLELL-HGDGTIVGERGASLSGGQRARICLARAVYRRADVYL 580

  Fly   570 LDDPLSAVDTHVGRHLFDQCMRGYLRSELVILVTHQLQFLEQADLIVIMDKGRISAMGTYSSMKR 634
            ||||||||||||||||||:||||:|..:|||||||||||||.||||||||||.:||.|||..|.:
  Fly   581 LDDPLSAVDTHVGRHLFDECMRGFLGKQLVILVTHQLQFLEDADLIVIMDKGHVSACGTYEEMLK 645

  Fly   635 SGLDFAQLLTAPNKDAEDLDEIDGAGGDGLDLLNVPSLSRRGSKNSKPSTRNNSFTSLSSMAE-S 698
            ||.||||||....:::        .|||  :::..|:|||:.|..|..|: |.|.:||.||.| .
  Fly   646 SGQDFAQLLVESTQNS--------GGGD--EIITSPNLSRQSSALSTKSS-NGSSSSLESMVEKE 699

  Fly   699 MAQEASLQMQETRVEGKIGLGLYKEYLTSGSSWFMIFFMVFLCLATQILCSAADYFLSYWVDKNV 763
            ..:.:::..||:|..|:|||.:||:|..:|....:...::.||:.||||.|..||||||||....
  Fly   700 KPKPSAVSSQESRSGGQIGLSMYKKYFGAGCGVLVFVVLIMLCIGTQILASGGDYFLSYWVKNTA 764

  Fly   764 DGQTDINTDPQDMYYFAALNVAVVVFTIVRTMLFYKMAMRSSTQLHNAMYQGITRAAMYFFNTNP 828
            ...|      .|:|||.|:||.:|:..::||:||:.:.|.|||:|||.|:||::|.|:|||:|||
  Fly   765 SSST------LDIYYFTAINVGLVICALLRTLLFFNITMHSSTELHNTMFQGLSRTALYFFHTNP 823

  Fly   829 SGRILNRFSKDLGQLDEVLPSVMLDVVQLFLTLLGIIVVICITNPYYLILTLALAIIFYYIREFY 893
            ||||||||:.||||:|||:|:||||.:|:||||.|||.|:|:|||:|||.|.|:.:.|||.|:||
  Fly   824 SGRILNRFANDLGQVDEVMPAVMLDCIQIFLTLTGIICVLCVTNPWYLINTFAMMLAFYYWRDFY 888

  Fly   894 LKTSRDVKRLEAVARSPIYSHLSATITGLPTIRALGAQKELIAEFDNLQDLHSSGYYTFLATNRA 958
            |||||||||||||||||:|||.|||:.|||||||:|||:.||.::||.|||||||||||::|:||
  Fly   889 LKTSRDVKRLEAVARSPMYSHFSATLVGLPTIRAMGAQQTLIGQYDNYQDLHSSGYYTFVSTSRA 953

  Fly   959 FGYYLDCFCTLYIVIIILNYFINPP-QSPGEVGLAITQAMGMTGMVQWAMRQSAELENTMTAVER 1022
            ||||||.||..|::.:||:.|.||| .:.|::|||||||:||||||||.|||||||||.||:|||
  Fly   954 FGYYLDLFCVAYVISVILHNFFNPPLHNAGQIGLAITQALGMTGMVQWGMRQSAELENAMTSVER 1018

  Fly  1023 VVEYDEIEPEGEFDSREGKKPSPSWPEKGEIIAEDLCLRYFPDPQAKYVLKALNFRIRPCEKVGI 1087
            |:||.:::|||:|:|...|:|..|||::|:::.:||.|||.||..:..|||.|:|.|:|.|||||
  Fly  1019 VLEYKDLDPEGDFNSPAEKQPPKSWPKEGKLVTKDLSLRYEPDTNSPCVLKGLSFTIQPMEKVGI 1083

  Fly  1088 VGRTGAGKSSLINALFRLSYNEGIITIDERDTADMGLFDLRSKISIIPQEPVLFSGSMRYNLDPF 1152
            |||||||||||||||||||||:|.|.||..||.|:||.||||||||||||||||||:||||||||
  Fly  1084 VGRTGAGKSSLINALFRLSYNDGAILIDSLDTNDIGLHDLRSKISIIPQEPVLFSGTMRYNLDPF 1148

  Fly  1153 EEYNDAKLWDALEEVKLKPLISELPNGLQSKISEGGSNFSVGQRQLVCLARAILRENRVLVMDEA 1217
            |:|.|.|||.|||:|.||..|||||:||||.|||||:|||||||||||||||||||||:||||||
  Fly  1149 EQYPDDKLWKALEDVHLKEEISELPSGLQSIISEGGTNFSVGQRQLVCLARAILRENRILVMDEA 1213

  Fly  1218 TANVDPQTDALIQATIRSKFRDCTVLTIAHRLNTIMDSDRVLVMDAGHLVEFGSPYELLTSSESK 1282
            |||||||||||||||||:||:||||||||||||||||||:||||||||:|||||||||||:|::|
  Fly  1214 TANVDPQTDALIQATIRNKFKDCTVLTIAHRLNTIMDSDKVLVMDAGHVVEFGSPYELLTASKAK 1278

  Fly  1283 IFHGMVMETGQNTFDSLLKVAE 1304
            :||||||:||:.:||.||||||
  Fly  1279 VFHGMVMQTGKASFDHLLKVAE 1300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrp4	NP_650086.2	MRP_assoc_pro	13..1292	CDD:188098	807/1299 (62%)
CG31793	NP_609930.4	PLN03130	10..1305	CDD:215595	817/1313 (62%)