Protein Alignment CG6689 and si:ch211-119o8.6

DIOPT Version :10

• Sequence 1: NP_650051.1
• Gene: CG6689 / 41345
• FlyBaseID: FBgn0037877
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001108212.1
• Gene: si:ch211-119o8.6 / 556659
• ZFINID: ZDB-GENE-070912-17
• Length: 735
• Species: Danio rerio
• Alignment Length: 554
• Identity: 133/554 - (24%)
• Similarity: 202/554 - (36%)
• Gaps: 130/554 - (23%)

  Fly   139 QDSVYLSETVTMELDPLSGEEKLEELQKCRTCYNDFTADFRAKDLFDPANSVLLFHIEVISGVWI 203
            :|||.|.....:..:.|....:|.:..:|..|            |.:...||||.|:.      |
Zfish    19 KDSVVLRCLHCLCKNCLQSYWELNKSLECPVC------------LKETRCSVLLHHLS------I 65

  Fly   204 SHKPDEPRL-----MCPACKSALDQAIDFREMCIS------TELKLSQAKPSTDEVQIEAENENP 257
            |....|...     ..|.....|:..:...|..||      ..:|..:...:..::.:|.:.|..
Zfish    66 SRFASEGEFSQDSNFKPLHVGNLESEMQLEETTISQVMSTIPRIKTEEDMTTIVQMLMETKYEPV 130

  Fly   258 ISSDHDLISDTENTNVEEIEDAGGDHVEDEATSDD-------QTSQEAVDEVAESPAAQDP-LSV 314
            .:|..|||......::..::....:.|.:|....|       .||...:.|..:|  .:.| ||.
Zfish   131 ETSIDDLIYTPTIEDISSVKREPSNEVSNEEIHRDLMIHDTVPTSSSVLTEPNDS--GEPPHLST 193

  Fly   315 ALGAKIFKELLDQYTGKEKARLRKGAPIASKPKAKEKAAGEQKPKR-SANPKTKEERN------- 371
            ....:..:..|....||...|       .|..:|.||....|||.: |...|:..:|:
Zfish   194 TTTCRSLRSNLCLKCGKSFER-------KSDLRAHEKVHSLQKPHQCSTCGKSYVDRHELSMHER 251

  Fly   372 ----------------LIRRAQLR--------AKPPNFVCDQCGQAFRMSHNLRIHMLRHTRTKN 412
                            .:|.:.|:        .||  |.|.|||::|.....|..|:..|.....
Zfish   252 LHTGEKLFDCSYCKKKFVRESALKYHLRSHTGEKP--FSCSQCGKSFSRRSTLNTHLRLHMGPLP 314

  Fly   413 YQCTECPKTFYDAYMRNMHIRIRHRGETPFACGFCSETFAYPGARQKHESEVH---NAAPRLIVK 474
            :||..|.|.|..|.....| |..|.||.||.|..|.:.|.:     |.|.|||   :|..:....
Zfish   315 HQCDHCGKLFNTAAAMRAH-RATHTGERPFPCPQCDKKFIF-----KAELEVHLDGHAGNKPFKC 373

  Fly   475 RINPKPMPKPRESVRYQ----------CKLCQKHYASKYALGWHIKSHTDANAYKCQRCSKSYSD 529
            .:..|...:.:|...:|          |..|...:.....|..|:|.|...:.:||..|.||:..
Zfish   374 SVCGKGFLRKQECNVHQTIHQDKRSFHCTYCDNSFKRLSHLTSHLKIHYPESPHKCTYCEKSFKH 438

  Fly   530 PNKLKRHEMTHE-KRPLQCDVCLKGF---YQRTR-------------------------LREHEL 565
            ||.||.||..|. ::|..|:.|.|.|   ..|||                         |:.|::
Zfish   439 PNSLKLHERLHTGEKPYSCEHCGKRFPSSGDRTRHLAVHSEVKSYKCPKCDRRFRFKNSLQSHQV 503

  Fly   566 IHTGERPYWCEVCNVNFRYKYNMKSHANSKMHQD 599
            :||||||:.|:.|:.:|....|:|:|  |.:|.:
Zfish   504 MHTGERPFHCKKCDRDFARLANLKAH--SVVHTE 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..94	CDD:214951
		zf-AD	166..241	CDD:462262	17/85 (20%)
		zf-C2H2	385..407	CDD:395048	8/21 (38%)
		C2H2 Zn finger	387..407	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..436	CDD:275368	7/20 (35%)
		C2H2 Zn finger	444..460	CDD:275368	3/15 (20%)
		C2H2 Zn finger	492..512	CDD:275368	5/19 (26%)
		C2H2 Zn finger	520..540	CDD:275368	10/19 (53%)
		C2H2 Zn finger	547..567	CDD:275368	9/47 (19%)
		zf-met	573..597	CDD:463736	7/23 (30%)
		C2H2 Zn finger	575..591	CDD:275368	5/15 (33%)
si:ch211-119o8.6	NP_001108212.1	RING_Ubox	9..50	CDD:473075	7/30 (23%)
		C2H2 Zn finger	205..225	CDD:275370	7/26 (27%)
		C2H2 Zn finger	233..253	CDD:275368	3/19 (16%)
		COG5048	257..676	CDD:227381	80/289 (28%)
		C2H2 Zn finger	261..281	CDD:275368	2/19 (11%)
		C2H2 Zn finger	289..309	CDD:275368	7/19 (37%)
		C2H2 Zn finger	317..337	CDD:275368	7/20 (35%)
		C2H2 Zn finger	345..362	CDD:275368	7/21 (33%)
		C2H2 Zn finger	373..393	CDD:275368	3/19 (16%)
		C2H2 Zn finger	401..421	CDD:275368	5/19 (26%)
		C2H2 Zn finger	429..449	CDD:275368	10/19 (53%)
		C2H2 Zn finger	457..477	CDD:275368	7/19 (37%)
		C2H2 Zn finger	485..505	CDD:275368	2/19 (11%)
		C2H2 Zn finger	513..533	CDD:275368	7/21 (33%)
		C2H2 Zn finger	541..561	CDD:275368
		C2H2 Zn finger	569..589	CDD:275368
		C2H2 Zn finger	597..614	CDD:275368
		C2H2 Zn finger	626..647	CDD:275368
		C2H2 Zn finger	655..675	CDD:275368
		C2H2 Zn finger	683..703	CDD:275368
		C2H2 Zn finger	711..731	CDD:275368