Protein Alignment CG6689 and Zfp229

DIOPT Version :10

• Sequence 1: NP_650051.1
• Gene: CG6689 / 41345
• FlyBaseID: FBgn0037877
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001158148.1
• Gene: Zfp229 / 381067
• MGIID: 2679295
• Length: 705
• Species: Mus musculus
• Alignment Length: 574
• Identity: 131/574 - (22%)
• Similarity: 201/574 - (35%)
• Gaps: 182/574 - (31%)

  Fly   171 YNDFTADFRAK--DLFDPANSVLLFHIEVISGVWISHKPDEPRLMCPACKSALDQAIDFREMCIS 233
            :.|...||..:  :..|.|...|..      ||.:.:..:...:....||:  |......::.|.
Mouse    15 FRDVAVDFSQEEWECLDSAQRALYI------GVMLENYSNLVSVGIIVCKA--DLVPHLEQIYIP 71

  Fly   234 TELKLSQ--AKP--------STDEVQIEAENENPISSDHDLISDTENTNVEEI-----EDAGG-- 281
            ..:|:.:  |||        |..|:....:::|.|....|:  ..:::...||     |.:||
Mouse    72 WNVKIKEMVAKPGRESYRMCSESEIVFYQDSKNIIYEHVDI--QWKSSECNEIGKMLHESSGGWI 134

  Fly   282 ----------------DHVEDEATSDDQTSQEAVDEVAESPA--------------AQDPLSVAL 316
                            |:.:|........|:.......|.|.              ......:.:
Mouse   135 LCKTNNTPEICNKYRFDNHKDAYIESTNLSRHKSMHTEEEPCKYKDYGKSLSLFSNVSQSHGIYI 199

  Fly   317 GAKIFKEL------------LDQYTGKEKARLRK---GAPIASKPKAKEKAAGEQKP-------- 358
            |.|.:||.            |..::||...:.||   |....|.....::....:||
Mouse   200 GEKEYKECDKTFGSFPKLVQLRIHSGKNPQKCRKCRTGFRTCSSLSTHQRTYTGEKPWICTECDK 264

  Fly   359 --KRSANPKT--------------------------KEERNL---------------IRRAQLRA 380
              :..::.||                          :|.:|:               .|.:.|||
Mouse   265 AFRWLSDLKTHYRIHPGEKPFKCKECDRSFTFYNSLREHQNIHKGKLYKCWKCDKFFTRCSSLRA 329

  Fly   381 --------KPPNFVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCTECPKTF-YDAYMR---NMH-- 431
                    ||  |.|.:|.::|.|...||.|...||..|.|:|.||.|:| |.:.:|   |||
Mouse   330 HEKIHTGEKP--FKCKECIKSFYMLSQLRKHARTHTGEKPYKCKECDKSFTYSSSLREHQNMHAG 392

  Fly   432 -----------------IRIR---HRGETPFACGFCSETFAYPGARQKHESEVHNAAPRLIVKRI 476
                             :|..   |.||.||.|..|.::|......:|| :..|..
Mouse   393 KLYKCQECDKCFTWCSSLRAHEKIHTGEKPFKCKECGKSFCMLSQLRKH-ARTHTG--------- 447

  Fly   477 NPKPMPKPRESVRYQCKLCQKHYASKYALGWHIKSHTDANAYKCQRCSKSYSDPNKLKRHEMTHE 541
                 .||     |:||.|:|.:.....|..|.|.|.....|||:.|.|.:...:.||.|..||.
Mouse   448 -----EKP-----YKCKECEKSFTQCSTLRIHQKIHAGEKPYKCKECGKCFYKLSYLKVHYRTHT 502

  Fly   542 -KRPLQCDVCLKGFYQRTRLREHELIHTGERPYWCEVCNVNFRYKYNMKSHANS 594
             ::|.||..|.|||.|.:.|:.||.|||||:||.|..|:.:|.:....:.|.::
Mouse   503 GEKPYQCKECGKGFSQLSCLKSHERIHTGEKPYKCSECDKSFTHCSTCRRHQST 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..94	CDD:214951
		zf-AD	166..241	CDD:462262	13/73 (18%)
		zf-C2H2	385..407	CDD:395048	8/21 (38%)
		C2H2 Zn finger	387..407	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..436	CDD:275368	11/46 (24%)
		C2H2 Zn finger	444..460	CDD:275368	3/15 (20%)
		C2H2 Zn finger	492..512	CDD:275368	7/19 (37%)
		C2H2 Zn finger	520..540	CDD:275368	6/19 (32%)
		C2H2 Zn finger	547..567	CDD:275368	9/19 (47%)
		zf-met	573..597	CDD:463736	5/22 (23%)
		C2H2 Zn finger	575..591	CDD:275368	3/15 (20%)
Zfp229	NP_001158148.1	KRAB	13..73	CDD:214630	12/65 (18%)
		C2H2 Zn finger	205..223	CDD:275368	3/17 (18%)
		COG5048	<227..412	CDD:227381	38/186 (20%)
		C2H2 Zn finger	231..251	CDD:275368	4/19 (21%)
		C2H2 Zn finger	259..279	CDD:275368	2/19 (11%)
		C2H2 Zn finger	287..307	CDD:275368	2/19 (11%)
		C2H2 Zn finger	314..334	CDD:275368	4/19 (21%)
		COG5048	338..704	CDD:227381	79/241 (33%)
		C2H2 Zn finger	342..362	CDD:275368	7/19 (37%)
		C2H2 Zn finger	370..390	CDD:275368	8/19 (42%)
		C2H2 Zn finger	397..417	CDD:275368	1/19 (5%)
		C2H2 Zn finger	425..445	CDD:275368	5/20 (25%)
		C2H2 Zn finger	453..473	CDD:275368	7/19 (37%)
		C2H2 Zn finger	481..501	CDD:275368	6/19 (32%)
		C2H2 Zn finger	509..529	CDD:275368	9/19 (47%)
		C2H2 Zn finger	537..557	CDD:275368	4/20 (20%)
		C2H2 Zn finger	564..584	CDD:275368
		C2H2 Zn finger	592..612	CDD:275368
		C2H2 Zn finger	620..640	CDD:275368
		C2H2 Zn finger	648..668	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368