DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6689 and Zfp26

DIOPT Version :10

Sequence 1:NP_650051.1 Gene:CG6689 / 41345 FlyBaseID:FBgn0037877 Length:613 Species:Drosophila melanogaster
Sequence 2:NP_001394469.1 Gene:Zfp26 / 22688 MGIID:99173 Length:965 Species:Mus musculus


Alignment Length:609 Identity:143/609 - (23%)
Similarity:239/609 - (39%) Gaps:124/609 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 CGYTEESLKLKNPCICIEH-------FKDEDIEGSLKFEMGLAKKRTLRPGAVPCVNKSQESGSD 102
            |...||:........|:::       |:||.::.|.:.....|..:..:||||     :.|..:.
Mouse    18 CSQGEETEGESMLADCLKNCNKDFVTFQDEAVDFSEEEWTTKAPTQNSKPGAV-----AVEEHTS 77

  Fly   103 RARKERSQRRRNQELVAE---LLAEEEAKLIHPEATSFEQDSVYLSETVTMELDP----LSGEEK 160
            .|..|..::.:.::|..|   |......:....:|.:||..:|..::.....|||    |..:..
Mouse    78 LAAVELEKQLQTKDLAPEQDFLTRHTFMETQQVDAVTFEDVAVDFTQEEWTSLDPVQRNLYRDVM 142

  Fly   161 LEELQKCRTCYNDFTADFRAKDLFDPANSVLLFHIEVISGVWISHKPD----------EPRLMCP 215
            ||..|...|.         ...:|.|:         :||  |:..|.:          |..:...
Mouse   143 LENYQNLATV---------GGQMFKPS---------LIS--WLEKKVELTVIEQGILQEWEMHLK 187

  Fly   216 ACKSALDQAIDFREMCISTEL--KLSQAKPSTDEVQIEAE-NENPISSDHDLISDTENTNVEEIE 277
            ..::||.|...:.:|....:|  :.|..:|. |.||:.|. :|:.....|...|:|.||....::
Mouse   188 TKRTALQQDRFWSDMSNGMQLGREHSGGEPG-DPVQVGAVFSEDSCPQTHSSTSNTGNTFACNLD 251

  Fly   278 DAGGDHVEDEATSDDQTSQ--EAVDEVAESP-------AAQDPLSVALGAKIFKELLDQYTGKEK 333
            ......:..|.::::...|  :.|..:..:|       ..:..:..:...:.|...|:..|.   
Mouse   252 GKDFQPLLKETSTEENIVQLNQCVKPLIFTPDVSQKKCTPEKSVECSDCGETFVNQLELQTH--- 313

  Fly   334 ARLRKGAPIASKPKAKEKAAGEQKPKRSANPKT----------------KEER--------NLIR 374
                     :|..:.|.....|:..:.|.:|.:                |.|:        |:..
Mouse   314 ---------SSSHREKNIHKSEECGQASTHPISHGGHVIPTEKKYYECKKCEKFFTHPVYLNIHM 369

  Fly   375 RAQLRAKPPNFVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCTECPKTFYDAYMRNMHIRIRHRGE 439
            ::....||  :.|.:||:||....:|.:|:.:|||.|:|:|.||.|||........|:| .|.||
Mouse   370 QSHTVEKP--YDCKECGKAFTERSSLIVHLRQHTREKSYECKECGKTFIQPSRLTEHMR-SHTGE 431

  Fly   440 TPFACGFCSETFAYPGARQKHESEVHNAAPRLIVKRINPKPMPKPRESVRYQCKLCQKHYA-SKY 503
            .|:.|..|...||.......|           :......||         ::|.:|.|.:. |.|
Mouse   432 KPYQCDQCGNAFASSSYLTTH-----------LRTHTGEKP---------FECNICGKAFTRSSY 476

  Fly   504 ALGWHIKSHTDANAYKCQRCSKSYSDPNKLKRHEMTHE-KRPLQCDVCLKGFYQRTRLREHELIH 567
            .|| ||::||....|:|:.|.|::|..:.|..|...|. :||..|..|.|.|....:|.||...|
Mouse   477 LLG-HIRTHTGEKPYECKVCGKAFSGRSWLTIHLRKHTGERPYPCTECEKAFTSFAQLTEHIKTH 540

  Fly   568 TGERPYWCEVCNVNFRYKYNMKSH 591
            |||:|:.|:||...||....:|:|
Mouse   541 TGEKPFRCKVCARTFRNSSCLKTH 564

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6689NP_650051.1 THAP 2..94 CDD:214951 13/55 (24%)
zf-AD 166..241 CDD:462262 14/86 (16%)
zf-C2H2 385..407 CDD:395048 7/21 (33%)
C2H2 Zn finger 387..407 CDD:275368 7/19 (37%)
C2H2 Zn finger 415..436 CDD:275368 8/20 (40%)
C2H2 Zn finger 444..460 CDD:275368 4/15 (27%)
C2H2 Zn finger 492..512 CDD:275368 9/20 (45%)
C2H2 Zn finger 520..540 CDD:275368 6/19 (32%)
C2H2 Zn finger 547..567 CDD:275368 7/19 (37%)
zf-met 573..597 CDD:463736 7/19 (37%)
C2H2 Zn finger 575..591 CDD:275368 6/15 (40%)
Zfp26NP_001394469.1 KRAB 113..171 CDD:214630 17/77 (22%)
C2H2 Zn finger 297..317 CDD:275368 4/31 (13%)
COG5048 325..760 CDD:227381 79/264 (30%)
C2H2 Zn finger 352..372 CDD:275368 3/19 (16%)
C2H2 Zn finger 380..400 CDD:275368 7/19 (37%)
C2H2 Zn finger 408..428 CDD:275368 8/20 (40%)
C2H2 Zn finger 436..456 CDD:275368 5/30 (17%)
C2H2 Zn finger 464..484 CDD:275368 9/20 (45%)
C2H2 Zn finger 492..512 CDD:275368 6/19 (32%)
C2H2 Zn finger 520..540 CDD:275368 7/19 (37%)
C2H2 Zn finger 548..568 CDD:275368 7/17 (41%)
C2H2 Zn finger 576..596 CDD:275368
COG5048 600..956 CDD:227381
C2H2 Zn finger 604..624 CDD:275368
C2H2 Zn finger 632..652 CDD:275368
C2H2 Zn finger 660..680 CDD:275368
C2H2 Zn finger 688..708 CDD:275368
C2H2 Zn finger 716..736 CDD:275368
C2H2 Zn finger 744..764 CDD:275368
C2H2 Zn finger 772..792 CDD:275368
C2H2 Zn finger 800..820 CDD:275368
C2H2 Zn finger 828..848 CDD:275368
C2H2 Zn finger 856..876 CDD:275368
C2H2 Zn finger 884..904 CDD:275368
C2H2 Zn finger 912..932 CDD:275368
C2H2 Zn finger 940..956 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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