Protein Alignment CG6689 and Zfp786

DIOPT Version :10

• Sequence 1: NP_650051.1
• Gene: CG6689 / 41345
• FlyBaseID: FBgn0037877
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001121066.1
• Gene: Zfp786 / 100158223
• RGDID: 2293500
• Length: 779
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 130/582 - (22%)
• Similarity: 216/582 - (37%)
• Gaps: 134/582 - (23%)

  Fly    72 SLKFEMGLAKKRTLRPG-AVPCVNKSQESG----SDRARKERSQRRRNQELVAELLAEEEAKLIH 131
            ||...:|..:..:|||. .:..||...:.|    |.::..|.:||:         :......|:.
  Rat   127 SLGLALGEREDVSLRPDQGISLVNAQTQHGEALVSVQSSSEAAQRK---------VLSSHKTLVL 182

  Fly   132 P---EATSFE--QDSVYLSETVTMELDPLSGEEK-LEELQKCRTCYNDFTADFRAKDLFDPA--- 187
            |   :.:|::  |.|..:....:.|.:.|..::| ..:...||. :..|:....||...|.:
  Rat   183 PGLQKVSSWQSTQHSCSVCGENSWEKNHLVKQQKGHSKSLSCRV-WKKFSRQADAKQQRDVSCPE 246

  Fly   188 -------NSVLLFHIEVISGVWISHKPDEPRLMCPACKSALDQAIDFREMCISTELKLSQAKPST 245
                   ...|:.|:::       |....|. .||.||           ||...|..|.
  Rat   247 CGKSFCLKQSLVRHLDL-------HLRKRPP-QCPKCK-----------MCFHHEHLLC------ 286

  Fly   246 DEVQIEAENENPISSDHDLISDTE---NTNV---EEIEDAGGDHVEDEATSDDQTSQEAVDEVAE 304
                  :.:...:||.|.. .||.   ::||   |::::......||.:....|....::|
  Rat   287 ------SHHLKQVSSQHPK-CDTSFPIDSNVHPCEQVQERPAFWKEDTSVPSRQKPGPSLD---- 340

  Fly   305 SPAAQDPLSVALGAKIFKELLDQYTGKEK--------------------ARLRKGAPIASKPKAK 349
               ::|  ....|:|:.....|...|:::                    .|...|......|::.
  Rat   341 ---SED--CCHTGSKLKYLQCDCILGEDRPCSCSECGSCFLSQSKQAGLCREHPGEKSLQCPESN 400

  Fly   350 ------------EKAAGEQKP--KRSANPKTKEERNLIRRAQLRAKPPNFVCDQCGQAFRMSHNL 400
                        :.....::|  .|..|........|....::.:...:|.|.|||:.|.....|
  Rat   401 KCLCLRGLQNVHQHVHSRERPFCCRKCNQGFTRHCRLTEHTRILSGEKSFWCAQCGKNFSQKAQL 465

  Fly   401 RIHMLRHTRTKNYQCTECPKTFYDAYMRNMHIRIRHRGETPFACGFCSETFAYPGARQKHESEVH 465
            ..|...||..|.:|||.|...|:.......| :::|.|..||:|..|...|||....::|.| ||
  Rat   466 LKHQRLHTEEKPFQCTLCELRFHLKSRLRAH-QLQHGGARPFSCSECGRAFAYQCKLREHLS-VH 528

  Fly   466 NAAPRLIVKRINPKPMPKPRESVRYQCKLCQKHYASKYALGWHIKSHTDANAYKCQRCSKSYSDP 530
            :.              .:|     :||..|.|.:..|..|..|.::|:....:.|..|.|.::..
  Rat   529 SG--------------ERP-----FQCPECHKSFRLKGILKAHQRTHSKERPFSCGECGKGFTRQ 574

  Fly   531 NKLKRHEMTHE-KRPLQCDVCLKGFYQRTRLREHELIHTGERPYWCEVCNVNFRYKYNMKSH 591
            :||..|...|. :||.||..|.:.|..:.:|..|:.:||||||:.|..|..::|.|.:||.|
  Rat   575 SKLTEHFRVHSGERPFQCPECDRSFRLKGQLLSHQRLHTGERPFQCPECGKSYRVKADMKMH 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..94	CDD:214951	6/22 (27%)
		zf-AD	166..241	CDD:462262	18/84 (21%)
		zf-C2H2	385..407	CDD:395048	8/21 (38%)
		C2H2 Zn finger	387..407	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..436	CDD:275368	5/20 (25%)
		C2H2 Zn finger	444..460	CDD:275368	5/15 (33%)
		C2H2 Zn finger	492..512	CDD:275368	6/19 (32%)
		C2H2 Zn finger	520..540	CDD:275368	6/19 (32%)
		C2H2 Zn finger	547..567	CDD:275368	5/19 (26%)
		zf-met	573..597	CDD:463736	7/19 (37%)
		C2H2 Zn finger	575..591	CDD:275368	6/15 (40%)
Zfp786	NP_001121066.1	KRAB	9..66	CDD:214630
		COG5048	228..581	CDD:227381	84/414 (20%)
		C2H2 Zn finger	244..264	CDD:275368	2/26 (8%)
		C2H2 Zn finger	272..290	CDD:275368	8/40 (20%)
		C2H2 Zn finger	368..388	CDD:275368	1/19 (5%)
		C2H2 Zn finger	396..416	CDD:275368	1/19 (5%)
		C2H2 Zn finger	424..444	CDD:275368	3/19 (16%)
		C2H2 Zn finger	452..472	CDD:275368	7/19 (37%)
		C2H2 Zn finger	480..500	CDD:275368	5/20 (25%)
		COG5048	<505..719	CDD:227381	48/152 (32%)
		C2H2 Zn finger	508..528	CDD:275368	7/20 (35%)
		C2H2 Zn finger	536..556	CDD:275368	6/19 (32%)
		C2H2 Zn finger	564..584	CDD:275368	6/19 (32%)
		C2H2 Zn finger	592..612	CDD:275368	5/19 (26%)
		C2H2 Zn finger	620..640	CDD:275368	7/17 (41%)
		C2H2 Zn finger	649..667	CDD:275368
		C2H2 Zn finger	675..695	CDD:275368
		C2H2 Zn finger	703..723	CDD:275368
		C2H2 Zn finger	731..751	CDD:275368