DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6689 and si:ch73-382f3.1

DIOPT Version :9

Sequence 1:	NP_650051.1	Gene:	CG6689 / 41345	FlyBaseID:	FBgn0037877	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001243612.1	Gene:	si:ch73-382f3.1 / 100151273	ZFINID:	ZDB-GENE-030131-9513	Length:	283	Species:	Danio rerio

Alignment Length:	322	Identity:	66/322 - (20%)
Similarity:	101/322 - (31%)	Gaps:	105/322 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CAVPNCRNFSDCRSKRNAAQQQRLGFFRFPKCPDTFKAWLAFCGYTEESLKLKNPC--ICIEHFK 65
            |:.|||.|.:....:          .|||||.|...:.||..|    ....:..||  :|.:||:
Zfish     4 CSAPNCSNSTTIGKQ----------LFRFPKDPVRMRKWLVNC----RRDFVPTPCSRLCQDHFE 54

  Fly    66 DEDIEGSLKFEMGLAKKRTLRPGAVPC-----------------------VNK------------ 95
            :...|...:...|   .|.|:|.|:|.                       |.|
Zfish    55 ESQFEEIARSPAG---GRKLKPNAIPTLFNVPDPPSPVTPQAVLPVKNEPVEKELNMGDHGYARR 116

  Fly    96 -----SQESGSDRARKERSQRRRNQELVAELLAEEEAKLIHPEATSFEQDSVYLSETVTMELDPL 155
                 |:|.|..||.:||                 ...|.....|..||..   ..||.::.:..
Zfish   117 QPPVDSEEDGVQRAEEER-----------------PCSLCQHYKTKLEQQQ---QHTVRLQREAE 161

  Fly   156 SGEEKLEELQKCRTCYNDFTADFRAKDLFDPANSVLLFHIEVISGVWISHKP--DEPRLMCPACK 218
            ..:::|.:|.|.......|        ||:.....|.........|| ||..  ...::.|....
Zfish   162 EMKKRLYKLSKIEKGLQVF--------LFEDQIRALTLAKRSRRAVW-SHDTLLTARKIRCAVGV 217

  Fly   219 SALDQAID-------FREMCISTELKLSQAKPSTDEVQ-----IEAENENP---ISSDHDLI 265
            ...:...:       :|.:|...|.|:..:....||:.     |.|..::|   ::||..||
Zfish   218 KGYEYLRELGYPLPSYRTLCNRLEPKMMVSTSMQDELAELGLGIIAACDSPEGNMTSDEGLI 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..96	CDD:283206	28/134 (21%)
		zf-AD	167..240	CDD:214871	13/81 (16%)
		zf-C2H2	385..407	CDD:278523
		C2H2 Zn finger	387..407	CDD:275368
		zf-H2C2_2	399..422	CDD:290200
		C2H2 Zn finger	415..436	CDD:275368
		C2H2 Zn finger	444..460	CDD:275368
		C2H2 Zn finger	492..512	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	547..567	CDD:275368
		zf-met	574..597	CDD:289631
		C2H2 Zn finger	575..591	CDD:275368
si:ch73-382f3.1	NP_001243612.1	THAP	4..81	CDD:283206	26/93 (28%)
si:ch73-382f3.1	NP_001243612.1	Tnp_P_element	146..>259	CDD:288840	22/124 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11471
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000