Protein Alignment mAcon2 and ACO1

DIOPT Version :10

• Sequence 1: NP_650042.2
• Gene: mAcon2 / 41326
• FlyBaseID: FBgn0037862
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: NP_195308.1
• Gene: ACO1 / 829737
• AraportID: AT4G35830
• Length: 898
• Species: Arabidopsis thaliana
• Alignment Length: 919
• Identity: 248/919 - (26%)
• Similarity: 367/919 - (39%)
• Gaps: 221/919 - (24%)

  Fly    11 LAGSMVRNFHTARFPRCDKVAMSNFDTGIPLPYKKLRENLDCIKGRLGGPLTLSEKVLYSHLDQP 75
            |..|.:||        ||:..:.:.|.                           ||:|......|
plant    46 LLESAIRN--------CDEFQVKSKDV---------------------------EKILDWENTSP 75

  Fly    76 DSQEIERGKSYLRLRPDRVALQDATAQMTLLQF---------ISSGLKKV--AVPSTVHCDHLIE 129
            ...||.       .:|.||.|||.|....::..         :.....|:  .||..:..||.::
plant    76 KQVEIP-------FKPARVLLQDFTGVPAVVDLACMRDAMNNLGGDSNKINPLVPVDLVIDHSVQ 133

  Fly   130 AQISGDKDLARAK-----DLNKEVYDFLS-SACAKYNLGFWKPGSGIIHQIILENYA-----FPG 183
            ..::..::..:|.     ..|||.:.||. .:.|.:|:....|||||:||:.||..|     ..|
plant   134 VDVARSENAVQANMELEFQRNKERFAFLKWGSNAFHNMLVVPPGSGIVHQVNLEYLARVVFNTNG 198

  Fly   184 LL----MIGTDSHTPNGGGLGCLCVGVGGADAVDVMANIPWELKCPTVIGCHLTGKISGWTSPKD 244
            ||    ::||||||....|||....||||.:|...|...|..:..|.|:|..||||:....:..|
plant   199 LLYPDSVVGTDSHTTMIDGLGVAGWGVGGIEAEATMLGQPMSMVLPGVVGFKLTGKLRDGMTATD 263

  Fly   245 VILKVAEILTVKGGTGAIVEYHGPGVESISCTGMATITNMGAEIGATTSIFPFNERMVTYLRATG 309
            ::|.|.::|...|..|..||:||.|:..:|....|||.||..|.|||...||.:...:.|||.||
plant   264 LVLTVTQMLRKHGVVGKFVEFHGEGMRELSLADRATIANMSPEYGATMGFFPVDHVTLQYLRLTG 328

  Fly   310 RGAIADEATK--------NK---DLLVPDEGCKYDKVIEINLDTLEPLVNGPFTPDLAHPISKLG 363
            |   :|:...        ||   |...|:....|...:|:||:.:||.|:||..|....|:.::.
plant   329 R---SDDTVSMIEAYLRANKMFVDYSEPESKTVYSSCLELNLEDVEPCVSGPKRPHDRVPLKEMK 390

  Fly   364 QNSEK--------------------------NGYPMEIK-----VSLIGSCTNSSYED-MGRCAS 396
            .:...                          ||...:::     ::.|.||||:|... |...|.
plant   391 ADWHSCLDNRVGFKGFAVPKEAQSKAVEFNFNGTTAQLRHGDVVIAAITSCTNTSNPSVMLGAAL 455

  Fly   397 IANDA--LGHGLKSCVPFNVTPGSEQVRATIARDGIIDVLEKFGGTVLANACGPCIGQWDRKDVK 459
            :|..|  ||..:|..:..::.|||..|...:|:.|:...|.:.|.:::...|..|||  :..|:.
plant   456 VAKKACDLGLEVKPWIKTSLAPGSGVVTKYLAKSGLQKYLNQLGFSIVGYGCTTCIG--NSGDIH 518

  Fly   460 MGEKNTI---------VTSYNRNFTGRNDANPATHC-FVTSPEMATALAIAGRLDFNPMTDEL-T 513
            ....:.|         |.|.||||.||  .:|.|.. ::.||.:..|.|:||.:|.:..|..: |
plant   519 EAVASAIVDNDLVASAVLSGNRNFEGR--VHPLTRANYLASPPLVVAYALAGTVDIDFETQPIGT 581

  Fly   514 GTDGKTFKLKE--PHGEE---------LPSKGFDPGEDTYQAPPAKADDIKVNVDPKSDRLQLLE 567
            |.|||....::  |..:|         ||    |..:.||:| ..|.:.:...:...|..|.
plant   582 GKDGKQIFFRDIWPSNKEVAEVVQSSVLP----DMFKATYEA-ITKGNSMWNQLSVASGTLY--- 638

  Fly   568 PFEKWDGKD-YI--------------------DLMVLIKIKGKCTTDHISAAG------PWLKY- 604
               :||.|. ||                    |...|:......||||||.||      |..||
plant   639 ---EWDPKSTYIHEPPYFKGMTMSPPGPHGVKDAYCLLNFGDSITTDHISPAGSIHKDSPAAKYL 700

  Fly   605 ----------------RGHLDNISNNMFIGATNAENNEMNKV--------KNQKTGSFDAVPAVA 645
                            ||:.:.::...|........:...:|        ..:|...|||    |
plant   701 MERGVDRRDFNSYGSRRGNDEIMARGTFANIRIVNKHLKGEVGPKTVHIPTGEKLSVFDA----A 761

  Fly   646 RDYKANKIKWCAVGEENYGEGSSREHAALEPRHLGGVAIIVKSFARIHETNLKKQGMLALTFANP 710
            ..|:........:....||.||||:.||..|..||..|:|.|||.|||.:||...|::.|.|...
plant   762 MKYRNEGRDTIILAGAEYGSGSSRDWAAKGPMLLGVKAVISKSFERIHRSNLVGMGIIPLCFKAG 826

  Fly   711 GDYDKV----QPSSKISI-LNLKDLAPGKPVDAEIKNNGSSDKIQLNHTLNELQIQWFQAGSAL- 769
            .|.:.:    |....|.: .|:.::.||:.|.. :.|||.|....|... .|:::.:|..|..|
plant   827 EDAETLGLTGQELYTIELPNNVSEIKPGQDVTV-VTNNGKSFTCTLRFD-TEVELAYFDHGGILQ 889

  Fly   770 ----NLMKE 774
                ||:|:
plant   890 YVIRNLIKQ 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAcon2	NP_650042.2	aconitase_mito	43..772	CDD:273561	239/883 (27%)
ACO1	NP_195308.1	PLN00070	1..898	CDD:215047	247/917 (27%)