Protein Alignment mAcon2 and mAcon1

DIOPT Version :10

• Sequence 1: NP_650042.2
• Gene: mAcon2 / 41326
• FlyBaseID: FBgn0037862
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: NP_524708.1
• Gene: mAcon1 / 44149
• FlyBaseID: FBgn0010100
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 774
• Identity: 614/774 - (79%)
• Similarity: 684/774 - (88%)
• Gaps: 2/774 - (0%)

  Fly     4 RTHRYICLAGSMVRNFHTARFPRCDKVAMSNFDTGIPLPYKKLRENLDCIKGRLGGPLTLSEKVL 68
            |..:::....::||.||.:.: ...|||:|.||:.:.|||:||.:.|:.::|||..|||||||||
  Fly    14 RLGKHVASEATVVRQFHASCY-TASKVALSKFDSDVYLPYEKLNKRLEVVRGRLNRPLTLSEKVL 77

  Fly    69 YSHLDQPDSQEIERGKSYLRLRPDRVALQDATAQMTLLQFISSGLKKVAVPSTVHCDHLIEAQIS 133
            |||||.|.:|:|.||.|||||||||||:|||||||.||||||||||||||||||||||||||||.
  Fly    78 YSHLDDPANQDIVRGTSYLRLRPDRVAMQDATAQMALLQFISSGLKKVAVPSTVHCDHLIEAQIG 142

  Fly   134 GDKDLARAKDLNKEVYDFLSSACAKYNLGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNGGG 198
            |.|||||||||||||||||:|.||||.||||||||||||||||||||||||||||||||||||||
  Fly   143 GPKDLARAKDLNKEVYDFLASTCAKYGLGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNGGG 207

  Fly   199 LGCLCVGVGGADAVDVMANIPWELKCPTVIGCHLTGKISGWTSPKDVILKVAEILTVKGGTGAIV 263
            ||.||:||||||||||||:||||||||.|||.:|||||||||||||||||||:|||||||||||:
  Fly   208 LGGLCIGVGGADAVDVMADIPWELKCPKVIGVNLTGKISGWTSPKDVILKVADILTVKGGTGAII 272

  Fly   264 EYHGPGVESISCTGMATITNMGAEIGATTSIFPFNERMVTYLRATGRGAIADEATK-NKDLLVPD 327
            ||||.||:||||||||||.|||||||||||:||||:||..||::|||..||.||.| ...:|..|
  Fly   273 EYHGKGVDSISCTGMATICNMGAEIGATTSLFPFNQRMADYLKSTGRAGIASEAQKYQAKILSAD 337

  Fly   328 EGCKYDKVIEINLDTLEPLVNGPFTPDLAHPISKLGQNSEKNGYPMEIKVSLIGSCTNSSYEDMG 392
            :.|:||::||||||||||.|||||||||.|||||||:||:||||||:|:|.||||||||||||||
  Fly   338 KNCEYDELIEINLDTLEPHVNGPFTPDLGHPISKLGENSKKNGYPMDIRVGLIGSCTNSSYEDMG 402

  Fly   393 RCASIANDALGHGLKSCVPFNVTPGSEQVRATIARDGIIDVLEKFGGTVLANACGPCIGQWDRKD 457
            ||||||.||:.|||||.:||||||||||:||||.||||.:|.:||||||||||||||||||||||
  Fly   403 RCASIAKDAMSHGLKSKIPFNVTPGSEQIRATIERDGISEVFDKFGGTVLANACGPCIGQWDRKD 467

  Fly   458 VKMGEKNTIVTSYNRNFTGRNDANPATHCFVTSPEMATALAIAGRLDFNPMTDELTGTDGKTFKL 522
            ||.|:||||||||||||||||||||||||||||||:.|||:|||||||||:||||||.|||.|||
  Fly   468 VKKGDKNTIVTSYNRNFTGRNDANPATHCFVTSPELVTALSIAGRLDFNPLTDELTGADGKKFKL 532

  Fly   523 KEPHGEELPSKGFDPGEDTYQAPPAKADDIKVNVDPKSDRLQLLEPFEKWDGKDYIDLMVLIKIK 587
            |.|.|:|||:||||||:|||.|||...:::||.|||||.||||||||:||:|:|..||.||||:|
  Fly   533 KAPFGDELPAKGFDPGQDTYTAPPPSGENVKVAVDPKSTRLQLLEPFDKWNGQDLTDLTVLIKVK 597

  Fly   588 GKCTTDHISAAGPWLKYRGHLDNISNNMFIGATNAENNEMNKVKNQKTGSFDAVPAVARDYKANK 652
            ||||||||||||||||||||||||||||||||||.||||||.:|||:.||:..||.||||||||.
  Fly   598 GKCTTDHISAAGPWLKYRGHLDNISNNMFIGATNYENNEMNNIKNQRNGSWGGVPDVARDYKANG 662

  Fly   653 IKWCAVGEENYGEGSSREHAALEPRHLGGVAIIVKSFARIHETNLKKQGMLALTFANPGDYDKVQ 717
            |||.|||:|||||||||||||||||||||.|||||||||||||||||||:|.||||||.||||:|
  Fly   663 IKWVAVGDENYGEGSSREHAALEPRHLGGRAIIVKSFARIHETNLKKQGLLPLTFANPADYDKIQ 727

  Fly   718 PSSKISILNLKDLAPGKPVDAEIKNNGSSDKIQLNHTLNELQIQWFQAGSALNLMKELA 776
            |:||||:||||.|||||||||||||....::|:||||||:|||.||:||||||.|||||
  Fly   728 PTSKISLLNLKSLAPGKPVDAEIKNGDKVERIKLNHTLNDLQIGWFKAGSALNRMKELA 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAcon2	NP_650042.2	aconitase_mito	43..772	CDD:273561	596/729 (82%)
mAcon1	NP_524708.1	aconitase_mito	52..782	CDD:273561	596/729 (82%)