Protein Alignment mAcon2 and aco2

DIOPT Version :10

• Sequence 1: NP_650042.2
• Gene: mAcon2 / 41326
• FlyBaseID: FBgn0037862
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: NP_944590.1
• Gene: aco2 / 322670
• ZFINID: ZDB-GENE-030131-1390
• Length: 782
• Species: Danio rerio
• Alignment Length: 765
• Identity: 551/765 - (72%)
• Similarity: 632/765 - (82%)
• Gaps: 2/765 - (0%)

  Fly    13 GSMVRNFHTARFPRCD-KVAMSNFDTGIPLPYKKLRENLDCIKGRLGGPLTLSEKVLYSHLDQPD 76
            |...|.||.|...... |||||.|:....:.|.|||.|:|.::.||..|||||||::|.|||.|.
Zfish    16 GQGSRRFHVAAALNAKAKVAMSRFEPSSYINYDKLRSNIDIVRKRLNRPLTLSEKIVYGHLDDPA 80

  Fly    77 SQEIERGKSYLRLRPDRVALQDATAQMTLLQFISSGLKKVAVPSTVHCDHLIEAQISGDKDLARA 141
            .|||.||::||||||||||:|||||||.:||||||||.|||||||:|||||||||..|.:||.:|
Zfish    81 GQEIARGRTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQTGGAQDLQKA 145

  Fly   142 KDLNKEVYDFLSSACAKYNLGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNGGGLGCLCVGV 206
            |::|:|||.||:||.|||.:|||||||||||||||||||:||:::|||||||||||||||:|:||
Zfish   146 KEVNQEVYSFLASAGAKYGVGFWKPGSGIIHQIILENYAYPGVMLIGTDSHTPNGGGLGCICIGV 210

  Fly   207 GGADAVDVMANIPWELKCPTVIGCHLTGKISGWTSPKDVILKVAEILTVKGGTGAIVEYHGPGVE 271
            ||||||||||.||||||||.|||..|||.:|||:||||||||||.|||||.|||||||||||||:
Zfish   211 GGADAVDVMAGIPWELKCPNVIGVKLTGSLSGWSSPKDVILKVAGILTVKRGTGAIVEYHGPGVD 275

  Fly   272 SISCTGMATITNMGAEIGATTSIFPFNERMVTYLRATGRGAIADEATKNKDLLVPDEGCKYDKVI 336
            ||||||||||.|||||||||||:||||.||.|||..||||.||..|.:||||||||.||.||::|
Zfish   276 SISCTGMATICNMGAEIGATTSVFPFNHRMKTYLDKTGRGEIATLADENKDLLVPDSGCHYDQLI 340

  Fly   337 EINLDTLEPLVNGPFTPDLAHPISKLGQNSEKNGYPMEIKVSLIGSCTNSSYEDMGRCASIANDA 401
            |||||.|:|.:|||||||||||:|.:|..:||||:|:::||.|||||||||||||||.||:|..|
Zfish   341 EINLDELKPHINGPFTPDLAHPVSDIGSVAEKNGWPLDVKVGLIGSCTNSSYEDMGRAASLAKQA 405

  Fly   402 LGHGLKSCVPFNVTPGSEQVRATIARDGIIDVLEKFGGTVLANACGPCIGQWDRKDVKMGEKNTI 466
            |..|||....|.|||||||:||||.|||...||...||.|||||||||||||||:|||.||||||
Zfish   406 LDKGLKCKAQFTVTPGSEQIRATIERDGYAKVLRDVGGIVLANACGPCIGQWDRRDVKKGEKNTI 470

  Fly   467 VTSYNRNFTGRNDANPATHCFVTSPEMATALAIAGRLDFNPMTDELTGTDGKTFKLKEPHGEELP 531
            |||:|||||.|||||||||.||||||:.|||||||.|.|||.||.||..:|:.|||:.|.|:|||
Zfish   471 VTSFNRNFTARNDANPATHAFVTSPEIVTALAIAGTLKFNPETDYLTAPNGEKFKLEPPTGDELP 535

  Fly   532 SKGFDPGEDTYQAPPAKADDIKVNVDPKSDRLQLLEPFEKWDGKDYIDLMVLIKIKGKCTTDHIS 596
            ::.||||:||||.|||....:||:|:|:|:||||||||:||:|||..||.||||:||||||||||
Zfish   536 ARDFDPGQDTYQHPPADGSALKVDVNPQSNRLQLLEPFDKWNGKDLEDLQVLIKVKGKCTTDHIS 600

  Fly   597 AAGPWLKYRGHLDNISNNMFIGATNAENNEMNKVKNQKTGSFDAVPAVARDYKANKIKWCAVGEE 661
            |||||||:||||||||||:.|||.|.||:.:||::|..||.:..||.|||.||.|.|.|..||:|
Zfish   601 AAGPWLKFRGHLDNISNNLLIGAVNIENDGVNKLRNLLTGEYSGVPDVARHYKKNNISWVVVGDE 665

  Fly   662 NYGEGSSREHAALEPRHLGGVAIIVKSFARIHETNLKKQGMLALTFANPGDYDKVQPSSKISILN 726
            ||||||||||||||||||||.|||||||||||||||||||:|.|||:||.||||::|..||||:.
Zfish   666 NYGEGSSREHAALEPRHLGGRAIIVKSFARIHETNLKKQGLLPLTFSNPADYDKIRPDDKISIIG 730

  Fly   727 LKDLAPGKPVDAEIKN-NGSSDKIQLNHTLNELQIQWFQAGSALNLMKEL 775
            ||..|||||:.|.||: :|||:.|:||||.||.||:|||||||||.|||:
Zfish   731 LKSFAPGKPLKAVIKHTDGSSETIELNHTFNETQIEWFQAGSALNRMKEM 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAcon2	NP_650042.2	aconitase_mito	43..772	CDD:273561	537/729 (74%)
aco2	NP_944590.1	aconitase_mito	47..777	CDD:273561	537/729 (74%)