Protein Alignment Leash and Arrdc5

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_084075.1
• Gene: Arrdc5 / 76920
• MGIID: 1924170
• Length: 325
• Species: Mus musculus
• Alignment Length: 231
• Identity: 56/231 - (24%)
• Similarity: 96/231 - (41%)
• Gaps: 37/231 - (16%)

  Fly    14 DRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLFYTSKEVYE 78
            |.||.||.||.|::.:.:|.......:||::.|:|..:|.|.:   ....:|||.:...:|..|.
Mouse    14 DAVYLAGSIIDGQVVLTLNSTLVDPVVKVELVGRGYVEWNEEI---GETRDYSRDVICNNKADYV 75

  Fly    79 HSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKY----------------KMR 127
            |.....|   .:...|.||.|||.|...|..:|||:|....|.|.|                |:.
Mouse    76 HKTKTFP---IKDNWLRAGSHTFDFHFNLPPRLPSTFNSKIGHISYFVQALCLDREHILAKKKLY 137

  Fly   128 VLIQRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVR 192
            :|:|....|.:|:.             .:.|:....||:|:......|.  ::|...:.::..|.
Mouse   138 LLVQGISEFRQRNL-------------SENSVSVEAEKKVSYNCCSQGW--VSLHVQMSKNTYVP 187

  Fly   193 GEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVP 228
            ||.:...:.:.|::...::.:.|.:..:|.|....|
Mouse   188 GEKVTFTSEIRNHTGKYIKTVVFALYAHVQYEGFTP 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	42/153 (27%)
		Arrestin_C	191..308	CDD:214976	8/38 (21%)
Arrdc5	NP_084075.1	Arrestin_N	13..127	CDD:451447	37/118 (31%)
		Arrestin_C	170..304	CDD:460676	10/56 (18%)