Protein Alignment Leash and si:dkey-172m14.1

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001188367.3
• Gene: si:dkey-172m14.1 / 567451
• ZFINID: ZDB-GENE-060526-221
• Length: 399
• Species: Danio rerio
• Alignment Length: 533
• Identity: 113/533 - (21%)
• Similarity: 179/533 - (33%)
• Gaps: 191/533 - (35%)

  Fly    20 GDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWME----ILRKNSNNNEYSRSLFY----TSKEV 76
            |||:.|.:.:.|.|...:..:.|::||....:|.|    ..|..|::..|.:...|    :||:.
Zfish    24 GDIVEGRVVLEVTKEINVENLFVKLTGDADVRWTEGSGDDERSYSDHERYFKQKQYFIQDSSKKG 88

  Fly    77 YEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVLIQRPW--TFDE 138
            .....|.|...|..|..:..|.|.|.|...|.:| :|.:|||.:|.:||.:.|.::|.|  |...
Zfish    89 QCEKNTTLVSGETYGSVIKPGSHVFPFRFQLPQQNMPPTFKGFHGWVKYIVMVKLKRSWKPTSSA 153

  Fly   139 RHTIPFTV----VKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVRGEPLRIC 199
            :..|.|..    ..:..|||.     |..|   .|.:.|||:..:::.....:...:.||.:|:.
Zfish   154 QAEINFAPRNFGTNDHLLQPQ-----SGTE---DKKMKLFGSGKMSMTVTTDKTGYMLGEIIRVS 210

  Fly   200 ATVINNSTTAVEKLRFTVLQYVTY-------YSHVPLRVQKVECIAVATKETGSVQKKTERSFAH 257
            ..:.|:|:..: ||::::.|..|:       ::|..:..:..:||....|          ..|..
Zfish   211 VDIDNSSSRDI-KLKYSLKQLQTFIAGRSTTHAHKDIVKETKDCIPSGGK----------TRFVV 264

  Fly   258 ELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLPFKVYSQDPSNRQSSLRPPP--- 319
            ::.||.....|.|... :|.:.|||:|           .|::.|   :.||:.:...:..||
Zfish   265 DIKLPHDIMVTIENCR-IIKVQYELKV-----------YLDVSF---ASDPTVKFPVVIIPPLQQ 314

  Fly   320 -PPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPSHSSQFSECSSINSITSDSSAATLSPAV 383
             ||. :|.||
Zfish   315 CPPW-HDPPP------------------------------------------------------- 323

  Fly   384 GAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLPAYPPPESPQY 448
                                              ||||           |.|:|..||.
Zfish   324 ----------------------------------PYMP-----------PQPNLVPYPG------ 337

  Fly   449 SLLALTPPPAGVV-----AAPPTGGAAAGGAPAYSQLPSTSASASFLQPRQAPGAHELP--PSYE 506
               ...|||||:.     ..||..|.|||      ..|:.:|        ..||.|..|  |.|:
Zfish   338 ---GAAPPPAGLYPNLYDPVPPYPGTAAG------TFPNPNA--------MLPGFHPAPSAPVYD 385

  Fly   507 ELFGLANAPPGTP 519
            :......:.|..|
Zfish   386 QNQSTKESFPNAP 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	40/146 (27%)
		Arrestin_C	191..308	CDD:214976	25/123 (20%)
si:dkey-172m14.1	NP_001188367.3	None