Protein Alignment Leash and arrdc3a

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001073498.1
• Gene: arrdc3a / 566685
• ZFINID: ZDB-GENE-030131-2913
• Length: 414
• Species: Danio rerio
• Alignment Length: 390
• Identity: 95/390 - (24%)
• Similarity: 161/390 - (41%)
• Gaps: 64/390 - (16%)

  Fly    11 DSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLFYTSK- 74
            ||...|:.:||.:.|.:.:.|....:::::|:...|..|.:|.| .|...::..|:::  ||.:
Zfish    18 DSNVPVFSSGDSVSGRVIIEVTGEIRVKSLKINAKGFAKVRWTE-SRNAGSSTAYTQN--YTEEV 79

  Fly    75 EVYEHSETPL-----PDFEPRGL-ELSAGEHTFIFEVALGR-QLPSSFKGSYGAIKYKMRVLIQR 132
            |...|.:..:     .|....|| .:.:|.|.:.|...|.: .|.:||:|.:|:::|.::..:.|
Zfish    80 EYLNHRDILIGHERDDDNSEEGLTTIHSGRHEYAFSFELPQTPLATSFEGKHGSVRYWVKAELHR 144

  Fly   133 PWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVRGEPLR 197
            ||....:....|||.:::.:.......|.:..|:.|.......:.||:|.|.:.......||.::
Zfish   145 PWLLPMKTKKEFTVFEHIDINTPLLLSPQAGTKEKTLCCWFCTSGPISLSAKIERKGYTPGESIQ 209

  Fly   198 ICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSVQKKTERSFAHELLLP 262
            |.|.:.|.|:..|.. :..:.|..|:::...::..| :.:|....|:.| ..|||......|.:|
Zfish   210 IFAEIENCSSRMVVP-KAAIYQTQTFFAKGKMKEIK-QLVANIRGESLS-SGKTETWNGKMLKIP 271

  Fly   263 DGAQPTDEQM--SGVITIVYELRVEAVLRGFFKNLILNLPFKVYSQDP----SNRQSSL------ 315
                |....:  ..:|.:.|.|.|...:.|.. ||.||||. |....|    .:|.||:
Zfish   272 ----PVSPSILDCSIIRVEYSLMVYVDIPGAM-NLSLNLPL-VIGTIPLHPFGSRTSSVSSQCSM 330

  Fly   316 -----------RPPPPP----------RPN--DGPPGPELGSGNL--------FEPALPVYPSLD 349
                       ||..||          |.|  :..||.|...|.|        |.|. |.|..:|
Zfish   331 TMSWLGMALPERPEAPPAYAEVVTEEQRQNCLEVSPGRENYDGPLFAYIQEFRFRPP-PPYSEID 394

  Fly   350  349
            Zfish   395  394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	37/148 (25%)
		Arrestin_C	191..308	CDD:214976	31/118 (26%)
arrdc3a	NP_001073498.1	Arrestin_N	22..165	CDD:425619	35/145 (24%)
		Arrestin_C	187..314	CDD:460676	35/135 (26%)