Protein Alignment Leash and CG14696

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_650035.1
• Gene: CG14696 / 41317
• FlyBaseID: FBgn0037853
• Length: 457
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 120/524 - (22%)
• Similarity: 202/524 - (38%)
• Gaps: 113/524 - (21%)

  Fly     3 SERLRITLDSAD-RVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYS 66
            |.::....||.. .:|.||.:|.|...:...:...||:|.:.:.|.|:.:|.|...:...:.:.:
  Fly     2 SSKVNFVFDSNPLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGEDGKTT 66

  Fly    67 RSLF-YTSKEVYEHSETPLPDFEPRG---LELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMR 127
            :||. :|:.|||..::.|:  :...|   |||..|::.|.|...:....|:||.|::|.||:::.
  Fly    67 KSLVTHTTTEVYYSTDQPV--YGQAGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHGQIKHEVT 129

  Fly   128 VLIQRPWTFDERHTIPFTVVKNMPL-------QPMQRSIPSSLEKQVTKTISLFGT-RPITLLAL 184
            :.|.|...::......|||:....|       :|:||     ||.:.....|:||. :|:.:...
  Fly   130 LTIDRAVRYNNTFKQCFTVILPHDLNRRLEYKEPLQR-----LESKSFWWGSIFGAHKPMIMDVS 189

  Fly   185 LPEDFAVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQ--KVECIAVATKETGSV 247
            ......|.|:.:.....:.|.|......::..:::.|:|.::.....:  ||....||.|..|.|
  Fly   190 TSYSAYVPGQKIHFHLVLDNQSDVQCMDVKVRLIKNVSYRANSSGAKEQLKVTESRVADKHCGEV 254

  Fly   248 QKKTERSFAHELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFK-----NLILNLPFKVYS-- 305
            .|..:..|...|.:|. ..|:.:.....|.:.|.||..|..   ||     :|:::.|..:.:
  Fly   255 LKHNKAKFDEFLTVPP-TTPSTQSEKDPIRVSYTLRFIAKT---FKLHGGGDLVMDFPITIGTVP 315

  Fly   306 -------QDPSNRQSSLRPPPPPRPNDGPP------GPELGSGNLFEPALPVYPSLDSSIGSPSH 357
                   :.|...:|.    |....:.|.|      ..|....|.|:|..|||| .|   |.|.
  Fly   316 LLGSADDKGPGAEKSQ----PSGASHPGSPNFQEDVSDEQFESNTFKPRYPVYP-FD---GKPG- 371

  Fly   358 SSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPY 422
                         |:.|:.|...|::                     .|.|..:..::.|.:.|.
  Fly   372 -------------TNGSNGAANFPSL---------------------YPKAEEAHPATPVKFTPN 402

  Fly   423 SSSPLMVQSYPPPHLPAYPPPESPQYSLLALTPPPAGVVAAPPTGGAAAGG---APAYSQLPSTS 484
            ..||...:|  ||:....|                   ||:||.|.....|   .|.|...||..
  Fly   403 PVSPAAQKS--PPYTTNTP-------------------VASPPGGNFEVLGFSIPPDYKPTPSAP 446

  Fly   485 ASAS 488
            |::|
  Fly   447 AASS 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	40/150 (27%)
		Arrestin_C	191..308	CDD:214976	27/132 (20%)
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:425619	40/151 (26%)
		Arrestin_C	182..316	CDD:460676	28/137 (20%)
		PHA03247	<313..450	CDD:223021	41/200 (21%)