Protein Alignment Leash and Arrdc4

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001380690.1
• Gene: Arrdc4 / 293019
• RGDID: 1311763
• Length: 415
• Species: Rattus norvegicus
• Alignment Length: 381
• Identity: 89/381 - (23%)
• Similarity: 145/381 - (38%)
• Gaps: 57/381 - (14%)

  Fly    11 DSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLF----- 70
            |.:...|.:|:.:.|.:.:...:...:|.::::..|:....|        ..:..:|...
  Rat    23 DESKGCYSSGETVAGHVLLEAAEPVTLRGLRLEAQGRATSAW--------GPSAGARVCIGGASP 79

  Fly    71 YTSKEVYEHSETPLPDFE-PRG---LELSAGEHTFIFEVALGRQLPS-----SFKGSYGAIKYKM 126
            ..|.|| |:....|...| |.|   ..|..|:|.|.|..    ||||     ||.|.||:|:|.:
  Rat    80 AASSEV-EYLNLRLSLLEAPAGEGVTLLQPGKHEFPFRF----QLPSEPLATSFTGKYGSIQYCV 139

  Fly   127 RVLIQRPWTFDERHTIPFTVVKNMPLQ--PMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDF 189
            |.:::||...|:.......||.::.:.  |:...:..:.||.|  ...||.:.|::|...:....
  Rat   140 RAVLERPQVPDQSVRRELQVVSHVDVNTPPLLTPMLKTQEKMV--GCWLFTSGPVSLSVKIERKG 202

  Fly   190 AVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSVQKKTERS 254
            ...||.:.|.|.:.|.|:..|.. :..:.|..||.:....:..:.....|.....||  ..|:..
  Rat   203 YCNGEAIPIYAEIENCSSRLVVP-KAAIFQTQTYLASGKTKTVRHMVANVRGNHIGS--GSTDTW 264

  Fly   255 FAHELLLPDGAQPTDEQMSG--VITIVYELRVEAVLRGFFKNLILNLPFKV----YSQDPSNRQS 313
            ....|.:|    |....:..  :|.:.|.|.|...:.| .|.|:|.||..:    || ....|.|
  Rat   265 NGKMLKIP----PVTPSILDCCIIRVDYSLAVYIHIPG-AKKLMLELPLVIGTIPYS-GFGRRNS 323

  Fly   314 S-----------LRPPPPPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPSHS 358
            |           |....|.:|...|...::.|...|...:|.||...:..|...:|
  Rat   324 SMASQFSMDMCWLALALPEQPEAPPNYADVVSEEEFSRHIPPYPQPSACDGEACYS 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	38/154 (25%)
		Arrestin_C	191..308	CDD:214976	29/122 (24%)
Arrdc4	NP_001380690.1	Arrestin_N	19..166	CDD:425619	38/155 (25%)
		Arrestin_C	188..315	CDD:214976	29/134 (22%)