Protein Alignment Leash and any2

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_594331.1
• Gene: any2 / 2542260
• PomBaseID: SPAC1F12.05
• Length: 377
• Species: Schizosaccharomyces pombe
• Alignment Length: 483
• Identity: 87/483 - (18%)
• Similarity: 145/483 - (30%)
• Gaps: 181/483 - (37%)

  Fly     6 LRITLDSADRVYFAG-DIIRGEIWMNVNKRTK--------------IRAIKVQVTGKGKC----- 50
            |.|.::|...|.:.. |:..|.:...:.|.|.              :|.|..:...:..|
pombe    20 LNIQMESPPLVMYGNPDVSSGALASGLAKLTVFPADLKCESIVMEFVRIISTKRPLRDSCPDCKA 84

  Fly    51 ------KWMEILRKNSNNNEYSRSLFYTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGR 109
                  ||           |:|:     ...||.|                 |.||:.|...:..
pombe    85 QVEAFEKW-----------EFSK-----EPTVYTH-----------------GTHTWPFTFIIPG 116

  Fly   110 QLPSSFKGSYGAIKYKMRVLIQRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLF 174
            ..|.:....:..:.|.::..::.|...|        .|...||. ::|||.::.:|...:   ||
pombe   117 HFPQTTNSPFINVTYILKTRVKIPSQPD--------FVFEYPLN-LKRSIVTNADKIAQR---LF 169

  Fly   175 GTRPITLLALLPEDFAVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAV 239
              .|.:|:|||                                        .:|..:..:.|:.|
pombe   170 --PPTSLIALL----------------------------------------ELPPVIHPLSCVPV 192

  Fly   240 ATKETGSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIV---YELRVEAVLRGFFKNLILNLP- 300
            ..:.|                   |.:|.:.::...:|.:   .|.:::|.:.|...:.....|
pombe   193 EFQLT-------------------GVKPENSKVGWRLTKISWRIEEQIKAQINGCSTHTGTKKPY 238

  Fly   301 -FKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGNLFEPALPVYPSLDSS-IGSPSHSSQFS- 362
             ||......:|...|             ...|.|...:||  :|:..||.|. |...|...|||
pombe   239 IFKETRLLGNNEHKS-------------GWKEDGDRIIFE--IPISTSLLSKPICDVSFDGQFSL 288

  Fly   363 -----------ECSSINSITSDSSAATLSPAVG---AGTGGMDMSYTSGSQ---SSQYGSPSART 410
                       ....:||...:|:|..|...|.   ...||:.:|:.....   :|...||.|..
pombe   289 YIAHQLILETIVVEVMNSHPINSNARILRMKVNLPLTERGGLGVSWDEECPPMFNSVGPSPPAYE 353

  Fly   411 SLRSSNVPYMPYSSSPLMVQSYPPPHLP 438
            .:..|:...:|          .|||..|
pombe   354 QVARSSPTDIP----------LPPPSCP 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	27/171 (16%)
		Arrestin_C	191..308	CDD:214976	13/121 (11%)
any2	NP_594331.1	LDB19	63..231	CDD:404030	42/273 (15%)