Protein Alignment Leash and aly2

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_596223.1
• Gene: aly2 / 2540410
• PomBaseID: SPBC2D10.04
• Length: 658
• Species: Schizosaccharomyces pombe
• Alignment Length: 538
• Identity: 103/538 - (19%)
• Similarity: 176/538 - (32%)
• Gaps: 192/538 - (35%)

  Fly    16 VYFAG-----------DIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSL 69
            :|.||           .::||.:.:.|.|...||.|.:..||:.:.:|.|.:....::.
pombe   158 LYLAGFDLNECQIENPALLRGALVLRVAKPANIRGISLSFTGRSRTEWPEGIPVKGHDT------ 216

  Fly    70 FYTSKEVYEHS--------------------------ETPLPDFEP---RGLELSA-GEHTFIFE 104
             |..|.:..|:                          :.|||....   ||..:.| ||:|:.|:
pombe   217 -YEDKVIISHNWKFYEPTMKDADAPQHGADVARLVGEQLPLPSSAAASLRGYSVFAPGEYTYNFD 280

  Fly   105 VALGRQLPSSFKGSYGAIKYKMRVLIQRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTK 169
            :|:....|.|.:...|.::|.:...::|..||..      .:....|:|.::...|:||......
pombe   281 LAIPNCFPESVEAKMGWVRYFLEATVERFGTFKS------NLNGRTPVQLVRTPSPASLSSSELI 339

  Fly   170 TISL-FGTRPITLLALLPEDFAVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQK 233
            .||. :..|       |..:..|.|:..|:...|       ....||.:|..|..|.   |.:..
pombe   340 NISRDWDER-------LHYELQVSGKSFRLGEVV-------PITFRFLLLDKVRLYK---LSISV 387

  Fly   234 VE-----CIAVATKETGSVQKK-----TERSFAHELLLPDGAQPTDEQMSGVITIVYEL------ 282
            ||     |   .:::...|..|     .|||..|:  ..|....|.::..|:.:.|:..
pombe   388 VESSEYWC---RSRKFHRVDPKRRVLLAERSAKHQ--NTDNLFETPDEGDGLSSAVFNFNVALPT 447

  Fly   283 ----------------------RVEAVL------------RGFFKNLILNLPFKVYS----QDPS 309
                                  |::|:|            |.:|: :.:..|.::.|    :|
pombe   448 CLVKERDRLTFDTTYKYIKVRHRLKALLVLSIENTENPEKRKYFE-INIETPVRILSCRCVKD-- 509

  Fly   310 NRQSSLRPPPPPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPSHSSQFSECSSINSITSDS 374
               |:|.||           .|..|....:..||....|.::...|         :.:.:.|:.|
pombe   510 ---STLLPP-----------YESSSQGDNQVLLPCPCRLATTHVEP---------TEVTAFTTQS 551

  Fly   375 SAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLPA 439
            ..|:.:|:.|.            ..::|...|:....:.|:|                |||....
pombe   552 VLASSAPSAGR------------PAAAQISRPAQLFRIPSTN----------------PPPFDGD 588

  Fly   440 YPPPESPQYSLLALTPPP 457
            ..||       ...||||
pombe   589 VCPP-------ACNTPPP 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	35/176 (20%)
		Arrestin_C	191..308	CDD:214976	30/170 (18%)
aly2	NP_596223.1	Arrestin_N	178..326	CDD:451447	33/160 (21%)
		Arrestin_C	345..506	CDD:214976	32/183 (17%)