Protein Alignment Leash and arrd-5

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_496119.1
• Gene: arrd-5 / 191469
• WormBaseID: WBGene00014161
• Length: 378
• Species: Caenorhabditis elegans
• Alignment Length: 335
• Identity: 83/335 - (24%)
• Similarity: 145/335 - (43%)
• Gaps: 43/335 - (12%)

  Fly    16 VYFAGDIIRGEIWMNV-NKRTKIRAIKVQVTGKGKCKWMEILRKNS---NNNEYSR----SLFYT 72
            |:..|:.:.|.:.|.: :...|.|.:::::.||....|...:|.|.   .|.:.:|    ...:.
 Worm    14 VFSPGEKVTGNVKMTIPDDEFKARKVRMEMIGKAYTYWEGNVRNNHTKIKNGDIARVRHNCADHK 78

  Fly    73 SKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLIQRPWTFD 137
            .|.||...||.:...:....::.:|.|.|.|...|....|.||:|..|.|:|.::|.|.|||.||
 Worm    79 GKIVYCRFETIVWKSDGAKNDMPSGPHIFPFSFQLPHWAPPSFEGDLGFIRYFIKVEIDRPWKFD 143

  Fly   138 ERHTIPFTVVKNMPLQPMQRS-IPSSLEKQVTKTIS--LFGTRPITLLALLPEDFAVRGEPLRIC 199
            ::.....||:.|:.|:.:..| :||  :|.|.:...  |:....:.:...||:...|.||.:.:.
 Worm   144 DKFITCLTVLPNIDLRLIPNSQVPS--KKHVCEEFGAVLWKNGLVRMELRLPKQGFVCGENIPVT 206

  Fly   200 ATVINNSTTAVEKLRFTVLQYVTY--------YSH-VPLRVQKVECIAVATK------------- 242
            ..|.|.::.:.:|:...::|.|||        .|| .|....:.|.|..||:
 Worm   207 MIVDNKTSKSFKKISLRLVQRVTYTGFRDGFVNSHSQPCIGNEKEKITYATRLNAQTRVEERQIS 271

  Fly   243 ETG---SVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFKNLI-LNLPFKV 303
            ||.   .:.|..::.....:.||  ..|...:...:|.:.|.|:|:....|..|:.: |.|.|.:
 Worm   272 ETNIDIKIDKNEKQEVEKPIPLP--PLPPSTKTCEIIDVEYFLKVKMSTSGALKSAVKLELAFII 334

  Fly   304 YSQ--DPSNR 311
            .:.  ||..:
 Worm   335 GTMPIDPERK 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	40/143 (28%)
		Arrestin_C	191..308	CDD:214976	32/144 (22%)
arrd-5	NP_496119.1	Arrestin_N	4..158	CDD:425619	40/143 (28%)
		Arrestin_C	182..338	CDD:214976	34/157 (22%)