Protein Alignment Leash and arrd-15

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001254970.1
• Gene: arrd-15 / 191372
• WormBaseID: WBGene00014033
• Length: 374
• Species: Caenorhabditis elegans
• Alignment Length: 312
• Identity: 72/312 - (23%)
• Similarity: 136/312 - (43%)
• Gaps: 52/312 - (16%)

  Fly     1 MESERLRITLDSADRVYFAGDIIRGEIWM-NVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNE 64
            |.:.::.|.|  |:....||:....::.: :.:..|.:.:...::.|.|:..|:.|
 Worm    33 MPTTQINIVL--AEPRCMAGEFFNAKVLLDSSDPDTVVHSFCAEIKGIGRTGWVNI--------- 86

  Fly    65 YSRSLFYTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVL 129
            ::..:|.|.| .|..::..|.|   .|..|..|:|.|..::.:....|||::..:|:|:|:|:|.
 Worm    87 HTDKIFETEK-TYIDTQVQLCD---SGTCLPVGKHQFPVQIRIPLNCPSSYESQFGSIRYQMKVE 147

  Fly   130 IQRPWTFDE---RHTIPFTVV-----KNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITL-LALL 185
            ::.  :.|:   ....|..::     .::||..|.   |...:.:|..|........::| ::|.
 Worm   148 LRA--STDQASCSEVFPLVILTRSFFDDVPLNAMS---PIDFKDEVDFTCCTLPFGCVSLNMSLT 207

  Fly   186 PEDFAVRGEPLRICATVINNST------TAVEKLRFTVLQYVTYYSHV---PLRVQKVECIAVAT 241
            ...|.: ||.:....| |||.|      .|::.:..|..:..:.|.||   .|..|.:|.:.:
 Worm   208 RTAFRI-GESIEAVVT-INNRTRKGLKEVALQLIMKTQFEARSRYEHVNEKKLAEQLIEMVPL-- 268

  Fly   242 KETGSVQKKTERSFAHELL-LPDGAQPTDEQMSG-----VITIVYELRVEAV 287
               |:|:.:....|...|| :||.|.||.....|     :|.|.|.|::.|:
 Worm   269 ---GAVKSRCRMEFEKCLLRIPDAAPPTQNYNRGAGESSIIAIHYVLKLTAL 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	31/154 (20%)
		Arrestin_C	191..308	CDD:214976	31/112 (28%)
arrd-15	NP_001254970.1	Arrestin_N	49..148	CDD:451447	26/111 (23%)
		Arrestin_C	198..333	CDD:460676	34/127 (27%)