Protein Alignment Leash and arrd-11

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_496883.2
• Gene: arrd-11 / 187635
• WormBaseID: WBGene00011052
• Length: 423
• Species: Caenorhabditis elegans
• Alignment Length: 486
• Identity: 112/486 - (23%)
• Similarity: 183/486 - (37%)
• Gaps: 105/486 - (21%)

  Fly     1 MESERLRITLDSADRVYFAGDIIRGEIWMN-VNKRTKIRAIKVQVTGKGKCKWMEI--LRK--NS 60
            |....|.:..|..:.|:|.|..|.|.:.:: ..::.|.||:.:::.|.....|.:.  :|:  |.
 Worm     1 MPETELHVIFDQPNEVFFPGQPISGRVVLSTTEEKYKARAVNIKILGLAHTSWTDYDSVRRVDND 65

  Fly    61 NNNEY-SRSLFYTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKY 124
            .|..| |.|:.|:|...|......|...:....|||||::.:.|...|...:|.||:|.||.::|
 Worm    66 GNVRYDSESVHYSSNVHYLDQALLLWACKDGSNELSAGDYVWPFSYTLPLNVPPSFEGKYGYLRY 130

  Fly   125 KMRVLIQRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSL-----EKQVTKTISLFGTRPITLLAL 184
            .:...:.|||..|:......||   .||..: .:||.:|     |:........|....:.|...
 Worm   131 SVTAEVDRPWRLDKAKRRCITV---SPLIDL-NAIPLALTPIDDEESENLGCCFFRKGYLELRVN 191

  Fly   185 LPEDFAVRGEPLRICATVINNSTTAVEKLRFTVLQ---YVTYYSHVPLRVQ-------------- 232
            :|:...|.||.:.:...::|:|:..|.:::..::|   ::.|.:....|..
 Worm   192 IPKTGFVPGETVPMNIHILNHSSVPVTEVKAKIIQQCKFIAYRNGTIFRFDGGSDTLMSGSSQQT 256

  Fly   233 KVECIAVATK-ETGSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVY--ELRVE------AVL 288
            |.:...|.|: :..:|....|..|..|..|| ...||..:.|.|||:.|  ::|||      :..
 Worm   257 KYDTKPVITQTQPMTVTPGNEHKFVLEFRLP-SVTPTICRFSPVITVEYVVQVRVETTSTCGSAA 320

  Fly   289 RGFFKNLILNLPFKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIG 353
            :.....||..:|.:.|.             |||.||:.|.|......||.:..:|
 Worm   321 KCEMPILIGTVPIRNYL-------------PPPIPNNYPIGLPPPYANLTDVNVP---------- 362

  Fly   354 SPSHSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVP 418
                      |                |:.|:||..:..:.....|.|.||..........:..|
 Worm   363 ----------C----------------PSGGSGTAVIPSAPPPSYQESMYGVGGTELRAEENEKP 401

  Fly   419 YMPYSSSPLMVQSYP-----PPHLPAYPPPE 444
            :.|         .||     |.:.|..||.|
 Worm   402 FAP---------KYPVFNNLPIYNPTAPPSE 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	42/151 (28%)
		Arrestin_C	191..308	CDD:214976	32/142 (23%)
arrd-11	NP_496883.2	Arrestin_N	6..159	CDD:425619	44/156 (28%)
		Arrestin_C	182..332	CDD:214976	32/150 (21%)