Protein Alignment Leash and arrd-24

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_510328.2
• Gene: arrd-24 / 185991
• WormBaseID: WBGene00009852
• Length: 346
• Species: Caenorhabditis elegans
• Alignment Length: 347
• Identity: 83/347 - (23%)
• Similarity: 137/347 - (39%)
• Gaps: 43/347 - (12%)

  Fly     8 ITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNE-----YSR 67
            |..|| .|.|..|..:.|::.:..|:....|.:|:.:.|....||.|..|:...|.|     |:.
 Worm     9 IVFDS-PRGYAPGQTVTGQVVLRSNEPITARFLKICIHGAAHTKWSEGERRYRTNCEGKEESYTE 72

  Fly    68 SLFYTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLIQR 132
            .:.|:::..|...||..........:|.:|.|.|.|...|..:.|.||:|.:|.::|.:||.:.|
 Worm    73 IVHYSAEVDYVSGETIAWSARNGTEKLPSGHHVFPFAFPLPIECPPSFEGFHGHVRYSVRVELDR 137

  Fly   133 PWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVRGEPLR 197
            ||.|::.....|.|:.|..|..:.......:.|.|.....:|....:|:...:|:.....||.|.
 Worm   138 PWKFNKNEREDFKVIPNFDLNHLPLGNVPRMMKDVKDIGQIFKKGIVTITVTIPKAGYAPGEYLP 202

  Fly   198 ICATVINNSTTAVEKLRFTVLQ---------------YVTYYSHVPLRVQKV----ECIAVATKE 243
            |...:.|.|..|...:|..:.|               :.:|:.|.....:::    :.|.:|.|.
 Worm   203 ITIDIDNASKRAATFVRAELHQHSHYNASKNHGLLCTHSSYHEHHKDESKRIAEARKSIKIAPKT 267

  Fly   244 TGSVQKKTERSFAHELL---LPDGAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLPFKVYS 305
            .|           .|:|   :|. :.||  ..|.:|:|.|.|.|.........| .|:..|.:..
 Worm   268 AG-----------REMLRMKIPK-SPPT--FTSPIISIEYCLSVRLDTLTTLNN-TLHCEFDIII 317

  Fly   306 QDPSNRQSSLRPPPPPRPNDGP 327
            ......:|.:.|.....|:|.|
 Worm   318 GTVPITESIVEPTVTTFPSDPP 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	43/148 (29%)
		Arrestin_C	191..308	CDD:214976	29/138 (21%)
arrd-24	NP_510328.2	Arrestin_N	7..158	CDD:425619	43/149 (29%)
		Arrestin_C	180..321	CDD:214976	31/155 (20%)