Protein Alignment Leash and arrd-17

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_499816.2
• Gene: arrd-17 / 176799
• WormBaseID: WBGene00011732
• Length: 426
• Species: Caenorhabditis elegans
• Alignment Length: 431
• Identity: 101/431 - (23%)
• Similarity: 171/431 - (39%)
• Gaps: 82/431 - (19%)

  Fly     1 MESERLRITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEY 65
            ::.:|..|..::.::.||||..|.|::.:...:..|:..|.:::.|:.:..|.:...|:..:..:
 Worm     2 VQLDRFEILFNNPEQAYFAGQEISGKVIIENKEPKKVNEILLELKGRARTYWTKHSGKSRKHCSH 66

  Fly    66 SRSLFYTS-KEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVL 129
            |...|... ...|.|..|.:.|.:.:...|.||.|...|...|.:.|||||:|.:|.|:|..:.:
 Worm    67 SEPYFLEQFNPGYTHKFTVVKDGKEKERILPAGIHQVPFSYTLPKSLPSSFEGEFGHIRYTCKAI 131

  Fly   130 IQRPWTFDERHTIPFTVV--KNMPLQPMQRSIPSSLEKQVTKTI------SLFGTRPITLLALLP 186
            .:|||.||......||||  :::...|......:.:|.....|.      |:.|...|:.....|
 Worm   132 CERPWDFDIVSRKAFTVVGIEDINSDPKLNEPATCVESNHAVTFCCRSAGSVTGEIRISKCGYTP 196

  Fly   187 EDFAVRGEPLRICATVIN-NSTTAVEKLRFTVLQYVTY-------YSHVPLRVQKVECIAVATKE 243
                  ||.:.:...||| :|.|....|||  :|..||       :.|:...|:.:..|......
 Worm   197 ------GEKIDVSFKVINLSSKTRTTALRF--VQQTTYKAKTFAGHEHIKNVVRVISKIDKGEVP 253

  Fly   244 TGSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVY--ELRVEAVLRGFFKNLILNLP----FK 302
            .||..:..|.|    :.:|  :.|.......::::.|  ||.||..|......:|.::|    ..
 Worm   254 GGSTTEWQEES----ITIP--SLPPKLGKCKILSVTYSVELEVEQTLTVPCPIVIGSIPQLSQLL 312

  Fly   303 VYSQ-------DPSNRQSSLRPPPPPRPND-----------GPPGPELGSGNLFEPAL------- 342
            ::|:       :.|..:||::..||...::           |....||  ||..|..|
 Worm   313 IHSKQSVQSAGNGSLPKSSIKDSPPKWDSESCVQVTITDESGQLVEEL--GNEMEALLSARKRVR 375

  Fly   343 -------PVYPSLD-----------SSIGSPSHSSQFSECS 365
                   .:||::.           |.|......:||.|.|
 Worm   376 MPSSILSELYPTMPSPYYKESFFGASDISEEKEQAQFGEAS 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	42/148 (28%)
		Arrestin_C	191..308	CDD:214976	31/137 (23%)
arrd-17	NP_499816.2	Arrestin_N	7..155	CDD:425619	42/147 (29%)
		Arrestin_C	179..307	CDD:460676	33/141 (23%)