Protein Alignment Leash and arrd-4

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_496120.1
• Gene: arrd-4 / 174540
• WormBaseID: WBGene00014159
• Length: 340
• Species: Caenorhabditis elegans
• Alignment Length: 300
• Identity: 60/300 - (20%)
• Similarity: 116/300 - (38%)
• Gaps: 52/300 - (17%)

  Fly     8 ITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGK---CKWMEILRKNSNNNEYSRSL 69
            |:.|.....|:.||.::|.:.:........|.:.::..||.:   ..|.::..|        :.|
 Worm    10 ISFDKQSEPYYPGDTVKGTVVLTNKTPLDARCVTIKCRGKSETYLINWTDLYCK--------KDL 66

  Fly    70 FYTSKEVY--EHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLIQR 132
            |..|:.|:  :..:..:|:          |.:.:.||:.|....|.:.:|..|...||::|.|.|
 Worm    67 FRKSEMVWVSKDGQNKMPE----------GGYIWTFEIKLPIDCPPTHEGYAGGTNYKVKVEIDR 121

  Fly   133 PWTFDERHTIPFTVVKNMPLQPM----QRSIPSSLEKQVTKTISLFGTR-PITLLALLPEDFAVR 192
            ||..:.|......|.:.:.::..    ..:..|:|..      .:|.:. ||:|...:|.....:
 Worm   122 PWKCNIREEKEIMVTRKLDIEKKWDQDGYTFTSNLRS------GIFSSNGPISLKVSVPTLVFRQ 180

  Fly   193 GEPLRICATVINNSTTAVEKLRFTVLQYVTYYSH-------------VPLRV----QKVECIAVA 240
            |:.......|.|:|::.:.::.....:.|.|:|.             .||.|    ....||..|
 Worm   181 GQTAEFHFEVKNHSSSTINEIFIKFGKQVHYHSRNQLTPCRKFDSHSCPLSVYHQTNSSNCIGEA 245

  Fly   241 TKETGSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVY 280
            |....:|...:.:|......:|:.|: |....:|::...|
 Worm   246 TALKVNVAPYSTKSIILPFTIPEEAK-TPSFSTGLVNFGY 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	32/148 (22%)
		Arrestin_C	191..308	CDD:214976	20/106 (19%)
arrd-4	NP_496120.1	Arrestin_N	8..141	CDD:425619	32/148 (22%)
		Arrestin_C	163..310	CDD:460676	24/122 (20%)