Protein Alignment Leash and arrd-1

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_493774.2
• Gene: arrd-1 / 173454
• WormBaseID: WBGene00020205
• Length: 291
• Species: Caenorhabditis elegans
• Alignment Length: 346
• Identity: 74/346 - (21%)
• Similarity: 132/346 - (38%)
• Gaps: 96/346 - (27%)

  Fly     6 LRITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLF 70
            |.|:.|..  ||:.||.::..:.::..:....|::..:..|...       |..|..|:|  .:.
 Worm     8 LDISFDKP--VYYPGDNMKLTVSVDTKRPLNARSVMFRCRGFRN-------RTVSFLNKY--GIA 61

  Fly    71 YTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLIQRPWT 135
            :..|:  ..:|.|:...|.:            |:..||:..|.::|.  |.|.||:|:.|.:||:
 Worm    62 WICKD--GKNELPVGRLEQK------------FQFELGKDCPPTYKD--GKIIYKVRLEIDQPWS 110

  Fly   136 ---FDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTIS-----LFGTRPITLLALLPEDFAVR 192
               |.|:.   |.:|..:..|.|        .:.:|.|.|     ||.....|....:|:.....
 Worm   111 RPLFIEKE---FKMVHKLADQKM--------SQVMTYTSSPRFDALFSNGQPTFKVTMPKFTLYP 164

  Fly   193 GEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSVQKKTERSFAH 257
            ||.......|.|:|::.|:|:          |:.:......:..|...||..|.:         |
 Worm   165 GETTEFKLEVENHSSSTVKKI----------YAELEAEPFPLYHIYGNTKAKGKM---------H 210

  Fly   258 ELLLPDGAQ--------PTDEQMS--------------GVITIVYELRVEAVLRGFFKNLILNLP 300
            .|:.|...|        |||...|              |::|..: |..:..|.     |::::.
 Worm   211 VLVAPYSTQKFTIPFTIPTDLTASFHTCGSSLKYTMKFGLVTDSW-LTTDPALA-----LVVSIG 269

  Fly   301 FKVYSQDPSNRQSSLRPPPPP 321
             ::.|::  .:..:|:.||||
 Worm   270 -ELESEE--KKDEALKTPPPP 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	34/148 (23%)
		Arrestin_C	191..308	CDD:214976	26/138 (19%)
arrd-1	NP_493774.2	Arrestin_N	8..122	CDD:451447	33/143 (23%)
		Arrestin_C	147..269	CDD:214976	27/146 (18%)