Protein Alignment Leash and arrdc1

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_031746886.1
• Gene: arrdc1 / 100485555
• XenbaseID: XB-GENE-486342
• Length: 452
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 99/512 - (19%)
• Similarity: 178/512 - (34%)
• Gaps: 152/512 - (29%)

  Fly     8 ITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLFYT 72
            |:|..:..:|..|:.:.|.:.:........:||.|             ||..      .:.|.::
 Frog     9 ISLRDSRVIYSPGEPLAGTVTIRTAAPLPYKAISV-------------LRSR------LQQLTHS 54

  Fly    73 SKEVYEHSETPL-----------PDFEPRGLELS-AG-----EHTF---------------IFEV 105
            .:::.:|:...|           |..:| |:.|: .|     .|||               :.|.
 Frog    55 LRQILQHTLQALHKRPPTLTKYVPSPQP-GINLAKVGPLDKCPHTFSSAEYVAPHPENAPTVLEK 118

  Fly   106 ALGRQLPSSFKGSYGAIKYKMRVLIQ-RPWTFDERHTIPFTVVKNMPLQPM----QRSIPSSLEK 165
            ...::..:||:|.:|.:.:::|..|: :..:.|.:....|.:::.:.|..:    ||:..|:
 Frog   119 LRPKRAATSFEGPFGKVTHQVRAAIETKRLSKDYKSAKLFYILRPLDLNEIPEIEQRNCASA--- 180

  Fly   166 QVTKTISLFGTRPITLLALLPEDFA--VRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVP 228
              ||..:....:...:|.....|..  |.|:.::|...:.|.|......:...::|.:.|.|.
 Frog   181 --TKKFNYLLVKSGQVLLAASSDLRGYVVGQAIQIHTELENKSGRDTGSIVAALVQKIAYKSK-- 241

  Fly   229 LRVQKVECIAVATKETGSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFK 293
             ||  |..:....:..|:..|..:|:...|.:|......:..|...:|.|.|.::|..      |
 Frog   242 -RV--VYDLRTIAEVEGAPVKAWKRAVWDEQILVPALPQSILQGCNLIHIDYYIQVTV------K 297

  Fly   294 NLILNLPFKVY-SQDPSN----RQSSLRPPPPPRPNDGPPGPELGSG----------------NL 337
            |..:::...:| ...|.|    ..|.|.|.|||.....||.....||                ..
 Frog   298 NPEVSVTLPIYIGNVPVNPMRLSHSVLHPTPPPVVPSAPPEDSDASGTSQTMESVSIPTKCHSQQ 362

  Fly   338 FEPALPV-------YPSLD---SSIGSPSHSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDM 392
            .:|.:|.       :|..|   .|:|||||                       ||:...||....
 Frog   363 QQPHVPFCYAPELHFPGSDDEAQSVGSPSH-----------------------PALCLSTGATVP 404

  Fly   393 SYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLP-AYPPPESPQY 448
            .::.|:.                 || :|.:|:.::    ||.:.. .||....|.|
 Frog   405 YFSDGAV-----------------VP-VPTASTLIL----PPEYSTWGYPYDAPPSY 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	30/176 (17%)
		Arrestin_C	191..308	CDD:214976	24/117 (21%)
arrdc1	XP_031746886.1	Arrestin_N	7..167	CDD:451447	30/177 (17%)
		Arrestin_C	190..313	CDD:214976	26/133 (20%)