Protein Alignment Cad86C and Cdhr1

DIOPT Version :10

• Sequence 1: NP_001247033.1
• Gene: Cad86C / 41302
• FlyBaseID: FBgn0261053
• Length: 1949
• Species: Drosophila melanogaster
• Sequence 2: NP_446024.1
• Gene: Cdhr1 / 93662
• RGDID: 620420
• Length: 859
• Species: Rattus norvegicus
• Alignment Length: 754
• Identity: 222/754 - (29%)
• Similarity: 332/754 - (44%)
• Gaps: 92/754 - (12%)

  Fly   123 ISLLIGILCPHHVQG--ADPKFD-----PTTRMRLVLVPADAQVNSVIYRLRATDEEFDYPLTFE 180
            ::|::|:||.:..|.  |...||     ....|.|..:|.|..|.|.:|.|..||.|.| |:::.
  Rat     7 VALVLGLLCIYLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGD-PISYH 70

  Fly   181 FVGDASASTVKVESLPCTKYNSVCQ--ANIVLQRRLEPGRYYDFQ--VSVKDTKGGMTTQ-LCSI 240
            ...|.|..:|          .||..  .||.|...|:..|..:.:  :|:.|....:..: :..:
  Rat    71 ISFDPSTRSV----------FSVDPNFGNITLVEELDREREDEIEAIISISDGLNLVAEKVVIVV 125

  Fly   241 TATNFTTPHDLIFPHKPGIIMIPEDAKRGTELDYVIARKNPLFQKPVYLELWGSPLFAIRQKIVS 305
            |..|...|.   |..:|..|::||:...|:.:..|.|.......        |..:....|.:.|
  Rat   126 TDANDEAPR---FLQEPYNILVPENTPAGSSIFKVQAEDKDTGS--------GGSVTYFLQSLHS 179

  Fly   306 SETT----EGTVFLL--GPLDFEKQAMYHLTILANDAYAE-PGQDSRNIAGMEIVVIVQDVQDQP 363
            |:.|    .|.:.|.  ..||:||...:.:|::|.|.... .|.|....|...:.:.|:||||..
  Rat   180 SKFTVDRHSGVLRLQAGATLDYEKSRAHFITVVAKDGGGRLRGADVVFSATTTVTINVEDVQDTA 244

  Fly   364 PVFTSAPPVTKLPPGILPGDKILQVHAEDGDKGNPREVRYGLVSENNPFTSFFDINETSGEIFLM 428
            |:|...|....:....|||.::|.|.|.|||:|.|..:.|.|::|::   ..|:||||||.|.::
  Rat   245 PIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESD---GLFEINETSGAISVL 306

  Fly   429 R---PLEDIAFITHVGDPVLLTVIAEEVKVGRDEPPALASTVQLAFFLPDRTNSPPYF------E 484
            :   .|....:..||          :..:|.....||..|||.:...:.|..|.||.|      :
  Rat   307 QSPAQLRREVYELHV----------QVTEVNSSGSPAAQSTVPVIIRIVDLNNHPPTFYGESGPQ 361

  Fly   485 NDHYVSRVDENAPHGTALTFVDPYVPRVYDDDTGKNGVFSLTLLNNNGTFEISPNVAERSAGFLI 549
            |...:| :.|:.|.|..|..:.   ..|.|.|.|.|..|:|.|:...|.|.:.|......|...|
  Rat   362 NKFELS-MFEHPPQGEILRGLK---ITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTI 422

  Fly   550 RVRDNSMLDYEQQQSVQFQILAQELGPATNLSALVNVTVYINDVNDNAPVFEQPAYSVELPENMT 614
            .|.:::.:|:|:.:|:.|::||.|:......|:..::.:.:.|.|||.|.|....|...:|||:.
  Rat   423 IVENSAAIDFEKSKSLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENVP 487

  Fly   615 AGTKVVQVLATDPDSGLGGKVRYTAILGYLNTSLNLDAETGLITVSTNKHGFDREVMPEYHLYVE 679
            .|:.||.|.|.|||:|..|||:| :|.|..:....:...|||| .:......|.|....|:.||:
  Rat   488 GGSNVVAVTAVDPDTGPWGKVQY-SIYGTGSDLFLIHPSTGLI-YTQPWASLDAEGTSRYNFYVK 550

  Fly   680 ARDMDGEGNRAQVPLIIKLIDVNDETPIFDKDLYEFILTHDLMGFTTTAVIHAEDKDATAPNNEV 744
            |.||||..:.|:|  .:.|:||||..|.|.:.:.|     ..|...|...|.|.|:||..|||.|
  Rat   551 AEDMDGRYSLAEV--FVTLLDVNDHYPQFVQSVQE-----KTMVLGTPLKIEATDQDAEEPNNLV 608

  Fly   745 RYEIINGNYDNQFVLDKVTGELTVREKIHLRSKKNAKTRRRRQAGSDDEDTDIFILTARAYDLGV 809
            .|.|......|.|.:|..|||:.::..|......:..|.....:.|         |..:|.|.|.
  Rat   609 DYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGEYSWS---------LQVQAKDRGS 664

  Fly   810 PVRFSTTT---IRVYPPE--SRKRSVKFVV-PGHNPDKA 842
            | .||||.   |.:...|  ||.....|:: ...||.||
  Rat   665 P-SFSTTALLKIDITDTERLSRSSMAAFLIQTKDNPMKA 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad86C	NP_001247033.1	Cadherin_repeat	260..361	CDD:206637	26/107 (24%)
		Cadherin_repeat	372..469	CDD:206637	31/99 (31%)
		Cadherin_repeat	487..596	CDD:206637	29/108 (27%)
		Cadherin_repeat	605..703	CDD:206637	38/97 (39%)
		Cadherin_repeat	728..820	CDD:206637	30/94 (32%)
		PTZ00449	<1428..1918	CDD:185628
Cdhr1	NP_446024.1	Cadherin_repeat	42..130	CDD:206637	24/98 (24%)
		Cadherin_repeat	139..242	CDD:206637	27/110 (25%)
		Cadherin_repeat	251..350	CDD:206637	33/111 (30%)
		Cadherin_repeat	364..469	CDD:206637	29/108 (27%)
		Cadherin_repeat	478..573	CDD:206637	39/98 (40%)
		Cadherin_repeat	580..679	CDD:206637	33/113 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	789..859