Protein Alignment Cad86C and Cad99C

DIOPT Version :10

• Sequence 1: NP_001247033.1
• Gene: Cad86C / 41302
• FlyBaseID: FBgn0261053
• Length: 1949
• Species: Drosophila melanogaster
• Sequence 2: NP_733314.1
• Gene: Cad99C / 43528
• FlyBaseID: FBgn0039709
• Length: 1706
• Species: Drosophila melanogaster
• Alignment Length: 1934
• Identity: 389/1934 - (20%)
• Similarity: 648/1934 - (33%)
• Gaps: 604/1934 - (31%)

  Fly   143 DPTTRMRLVLVPADAQVNSVIYRLRA----------TDEEFDYPLTFEFVGDASASTVKVESLPC 197
            ||.|.:.|.||....|   .|::|..          .|||....:.|: |...:.||.|..::|.
  Fly    68 DPDTEIALNLVFPKGQ---PIFQLNGKKLQLLQPLDRDEENLSHIVFQ-VSCTTRSTGKKRTIPI 128

  Fly   198 TKYNSVCQANIVLQRRLEPGRYYDFQVSVKDTKGGMTTQLCSITATNF-TTPHDLIFPHKP---- 257
            .                         |.|.|...         .|..| .||:::..|...
  Fly   129 I-------------------------VRVSDIND---------NAPRFMNTPYEVTVPESTPVGT 159

  Fly   258 ----GIIMIPEDAKRGTELDYVIARKNPLFQKPVYLELWGSPLFAIRQKIVSSETTEGTVFLLGP 318
                .|..:.:||.....::|.||..:|...........|...|||      |...:|.|.:...
  Fly   160 TIFRNIQALDKDAGVNGLVEYFIAEGSPNSTNVEKYSADGYGTFAI------SFPHQGQVTVAKT 218

  Fly   319 LDFEKQAMYHLTILANDAYAEPGQDSRNIAG-----MEIVVIVQDVQDQPPVFTSAPPVT----- 373
            |||||...|:|||:|:|.       :||.|.     ..:.|.:.|..|..|.|..:..|:
  Fly   219 LDFEKIQTYYLTIVASDR-------ARNTADRLSSTTTLTVNIADSNDLDPSFIYSGCVSLDGAC 276

  Fly   374 -------KLPPGILPGDKIL-----QVHAEDGDKGNPREVRYGLVSENNP--FTSFFDINETSGE 424
                   .:|.|.|.|  :|     ::.|.|.|..| ..:||...| ..|  :..:|.|:|::|.
  Fly   277 INPEYSASVPAGSLLG--VLTVLPERIQAVDLDTIN-SPIRYSFAS-GMPGNYADYFQIDESTGV 337

  Fly   425 IFLMRPLEDIAFITHVGDPVLLTVIAEEVKVGRDEPPALASTVQLAFFLPDRTNSPPYFENDHYV 489
            :...:.::     |.......:.|.||||..|    |...:|.:|..|:.....:||...:....
  Fly   338 LKQTKAVD-----TSTAKKYDIIVKAEEVSPG----PQRFTTAKLEIFVKPVDANPPVISSSQAE 393

  Fly   490 SRVDENAP--------HGTALTFVDPYVPRVYDDDTGKNGVFSLTLLNNNGTFEISPNVAERSAG 546
            ..||||:|        ||..::|:..... :.|.|...:.::.||          :|:......|
  Fly   394 GYVDENSPIGTRVLDAHGNPISFMTTDAD-LSDSDPKPDYIYELT----------TPSFNVTGDG 447

  Fly   547 FLIRVRDNSMLDYEQQQSVQFQILAQELGPATN-LSALVNVTVYINDVNDNAPVFEQPAYSVELP 610
            .|:...:|...|.......:||::|:|  |.|| .||.:::||::.|||||||.....|     |
  Fly   448 ILVVNEENLDRDPPAPGRFKFQVVARE--PRTNAASAPLSLTVHLRDVNDNAPKLAMVA-----P 505

  Fly   611 ENMTAGTK-----VVQVLATDPDSGLGGKVRYTAILGYLNTSL---NLDAETGLITVSTNKHGFD 667
            .::|||.:     |.||.|||.|.|....|.| :|....|..:   .::|.||.|.........:
  Fly   506 ISITAGDQSESRLVTQVTATDNDEGPNAVVTY-SIYHVSNNGIQKFTINATTGEIRTQGRLLAGE 569

  Fly   668 REVMPEYHLYVEARDMDGEGNRAQVPLIIKLIDV------NDETPIFDKDLYEFILTHDLMGFTT 726
                 :|.:.|:|.|:.|..::|       :::|      |.:.|.|.|.:||..::......:|
  Fly   570 -----QYSITVQATDIGGLSSQA-------IVEVSVTPGPNTKPPRFQKPIYEVQVSEGAEINST 622

  Fly   727 TAVIHAEDKDATAPNNEVRYEIINGNYDNQFVLDKVTGELTVREKIHLRSKKNAKTRRRRQAGSD 791
            ..|:||||.:    |:.|.|.||:||...||.:.:.:|.:.|..|:                  |
  Fly   623 VTVVHAEDPE----NDAVVYSIISGNDLRQFAVGQESGVIIVIRKL------------------D 665

  Fly   792 DEDTDIFILTARAYDLG-----VPVRFSTTTIRVYPPESRKRSVKFVVPGHNPDKAKTEETLSAL 851
            .|....:.|..:|.|.|     ..|....|.|....||....::.:|.        :.||..:..
  Fly   666 RESLTRYQLILKAEDTGGLSSSATVNIKVTDINDKNPEFEASTLPYVF--------QVEEGKAQA 722

  Fly   852 SGGKVYIHNIRPLSPDEPGAKDIPAGNPGIKERSVVTATVIYDSSSVVDISEIQQRLSHHNNSYA 916
            |.|.|:             |.|...|         :.|.:.|  |...||            .:.
  Fly   723 SVGVVH-------------ATDADEG---------INAEITY--SIPTDI------------PFT 751

  Fly   917 IMPQDTSSTDTLTPLQTQYKAENKVLFWLLILLATLVALTILILLLCCICSWCPLYGAATKRIVN 981
            |   :.:|.:.||..:..|:..|:..|                                   :|.
  Fly   752 I---NATSGEILTAKELDYEQLNEYKF-----------------------------------VVT 778

  Fly   982 ISRTEDDVHLVHREMANGKQTKSVQVAEWMGRRDAWSAEKPPDTRTKPTRWEFHDGREQLDEDVG 1046
            ......|..|       |..:.:|.|.:.            ||...|     |.|.|..:
  Fly   779 AKDGAPDARL-------GTASVTVMVLDL------------PDEVPK-----FSDARIDV----- 814

  Fly  1047 RGQDIGEGDRRHIQSAEEQQRRVRIKHNRTAKDDLHLNFHNSRTNLINDRDVYMEDVIENRDLAG 1111
                       ||...||                   ||      |:.....:..|
  Fly   815 -----------HIPENEE-------------------NF------LVATVQAFDPD--------- 834

  Fly  1112 DREHITRT-RVNRQEYARRKQYDSEVRHI---DDDSMRRHEIDRGSDIDFNTAHNSLKSKRELFI 1172
            ....||.. |....|..:..:...|||.|   |.:|.::|::..|      |..|
  Fly   835 SMPEITYVLRKGNAELFKVSEKSGEVRTIKGLDYESQKQHQLTIG------TIEN---------- 883

  Fly  1173 KDGN--VEILQLMTRDKTRDGL-------------NLDDDNIYVNVPLKPA--------GNL--- 1211
             |||  .:.:.|:...:.|:.|             | ||..|...:...||        ||:
  Fly   884 -DGNGPGDTILLVVDVEDRNDLPPRFITVPDPVTVN-DDQGIGTIIATLPAIDGDGTSPGNVVRY 946

  Fly  1212 ------SHPQLLMVD-NTGKEILMRRFIEEQPDGKQIIREHYQIVPGATYIQSMPNEVQQGSTLK 1269
                  ..|:...|| :||...:.....:|:....|:....|.:  |...:.|:       :.|:
  Fly   947 EIVGRGKAPKYFQVDPDTGAVRIRDELRKEEDTEYQVDIRAYDL--GEPQLSSV-------APLR 1002

  Fly  1270 GDTFPLGKSGPNSIVYSQLEPEVKVIHTQPVQAGEGVSLDQQMQPAVSNQSLTHELEHSLKQQNA 1334
            .|...|..||.|         |:|:  ...:::|.|:| .:.:..|.|:.|.|..:..|: :.|:
  Fly  1003 VDVHHLLSSGNN---------EIKL--DNKLESGTGMS-SESIGLAFSDDSYTTSVPESM-EANS 1054

  Fly  1335 LLRQILMEKEKLENAYTQHE--VALETQSLPGQSMAIGTQTDCDAG-----TQTEGFDGVLDPEI 1392
            .|:.|     ::.|:.|..:  .|...:.:.|....|...:..|.|     .|...|:......:
  Fly  1055 TLKLI-----QIVNSKTSGDGPPAFRCEFVSGNGGGIFNLSSADHGCNLLLIQPLDFENKSSYSL 1114

  Fly  1393 SLAKPSRRR--------------ARSENDESMSEDGYEYVRFNPPNSPEGVYWIKRRRTKKRPRQ 1443
            .|...|.|.              .:.|||                |:||..:      .:.|.:|
  Fly  1115 QLRLTSHRYFVNPLKDTTSVEIIVQDEND----------------NAPEFEF------NRLRGQQ 1157

  Fly  1444 PRKRIVMVEEVK-----RKIRTPIKEEEEV----------QERKKRVPPKKPLRETKTSILRKQL 1493
            .....|:.||:.     .::|...::..:.          .|.:..:|....:....|.:||...
  Fly  1158 DTFYTVVTEEMDVDTTILQVRATDRDSGKFGTVRYTLYDDDENRVNMPTSFFMMSEDTGVLRTAK 1222

  Fly  1494 SDESRKD-------QSRNGESQTGNRHRSE---------------------SDSHNRDMFMEITD 1530
            ..::..|       ::|:.:.|....||:.                     :.|..|:.:.|:.:
  Fly  1223 HFKNENDFPLTFLVEARDSDGQEQGSHRTRARIVVNKLADINRMALSFPNAAPSDLRNYYTELEE 1287

  Fly  1531 SMDELASPGSHSIRKIQVEKYYKHSDGDFDEDDTE-----YSIDSDGDEIVIRTNYPSRAQENER 1590
            .:|:.....| .|.::..:||.. .:|...|:...     |.||...:::|.|.:........|.
  Fly  1288 LLDKKTGLVS-GIERMSSQKYLA-KNGSVIENPAATDIWFYLIDPKTEQLVSRKDSIVETTLLEP 1350

  Fly  1591 YRRQERTYAEP----EN---PVDRKRPARK-SSPTDSQPEAMP---------------------- 1625
            ..|.|...|.|    ||   |::||....| .:......|..|
  Fly  1351 AARSELNIALPRATAENISFPLERKEHVHKVKAAVAIDNEVFPFTLIAISLVILILGTIGIIYIC 1415

  Fly  1626 -RLSRRDSSKRGSRKQTSSEPP-HNRVSISKYESTVTENGRKLMSTSTEIVGS--KRSLTD---R 1683
             ..|:..:.|:..|:.:|:.|| ::.|.:::..|:.:|....:....|:::..  ...:.|   .
  Fly  1416 ISWSKYKNFKQRMRQYSSTNPPRYDPVIVNQQASSASETIANMKEYETQMLAMAVPPDVDDDLQL 1480

  Fly  1684 SYQSETELAGLEHEERNVPKYMEWYYNKKKSSVSGRTSTESSKSQPSSKKKVGAAEKRVSKTRIT 1748
            .:.::.....|::        :.:..:|:.::..|::|...|.:..::     .|..|..|....
  Fly  1481 DFSAKNHAFSLDN--------VSYITHKENTNGGGQSSPSHSDATTAT-----IATLRRHKNLNN 1532

  Fly  1749 AQPKD---VEEYDETGGR-----YKPEPAPRKSPPKGSRLLKEDRALNK-QHKPKIETDTNHPLL 1804
            |...:   :.....|..|     .:....|..|||.|:  |.....|.: :|:     ::||  .
  Fly  1533 ASMNNNLAINNRQNTFNRTLEMNTRNNANPLASPPNGA--LSGTLTLGRIKHQ-----NSNH--Y 1588

  Fly  1805 QHSEHRFERENALEVPAAPTKLPHYMYPETPPHAAAGGKESKSGRESKT 1853
            |:..:..:       |..|..:.|          |.....|..||...|
  Fly  1589 QNGAYNID-------PTGPNNMAH----------AKNNAYSTMGRRGNT 1620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad86C	NP_001247033.1	Cadherin_repeat	260..361	CDD:206637	29/105 (28%)
		Cadherin_repeat	372..469	CDD:206637	27/115 (23%)
		Cadherin_repeat	487..596	CDD:206637	31/117 (26%)
		Cadherin_repeat	605..703	CDD:206637	27/111 (24%)
		Cadherin_repeat	728..820	CDD:206637	26/96 (27%)
		PTZ00449	<1428..1918	CDD:185628	85/520 (16%)
Cad99C	NP_733314.1	CA_like	68..140	CDD:481204	21/109 (19%)
		Cadherin_repeat	146..259	CDD:206637	32/125 (26%)
		Cadherin_repeat	280..383	CDD:206637	28/115 (24%)
		Cadherin_repeat	393..496	CDD:206637	31/115 (27%)
		Cadherin_repeat	518..594	CDD:206637	23/88 (26%)
		Cadherin_repeat	608..699	CDD:206637	29/112 (26%)
		Cadherin_repeat	710..802	CDD:206637	27/192 (14%)
		Cadherin_repeat	814..903	CDD:206637	27/155 (17%)
		Cadherin_repeat	915..1005	CDD:206637	19/99 (19%)
		Cadherin_repeat	1041..1144	CDD:206637	21/124 (17%)
		Cadherin_repeat	1159..1264	CDD:206637	14/104 (13%)