Protein Alignment Cad86C and stan

DIOPT Version :10

• Sequence 1: NP_001247033.1
• Gene: Cad86C / 41302
• FlyBaseID: FBgn0261053
• Length: 1949
• Species: Drosophila melanogaster
• Sequence 2: NP_001260871.1
• Gene: stan / 36125
• FlyBaseID: FBgn0024836
• Length: 3648
• Species: Drosophila melanogaster
• Alignment Length: 848
• Identity: 216/848 - (25%)
• Similarity: 343/848 - (40%)
• Gaps: 182/848 - (21%)

  Fly   122 TISLLIGIL-CPHHVQGADPKFDPTTRMRLVLVPADAQVNSVIYRLRATDE------EFDYPLTF 179
            |.:|.:.:| |..|    .|.|:  .......:...|.|.|.:..|||||:      |.:|.:
  Fly   447 TTTLQVNVLDCNDH----SPTFE--AEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGI-- 503

  Fly   180 EFVGDASASTVKVESLPCTKYNS---VCQANIVLQRRLEPGRYYDFQVSVKDTKGGMTTQLCSIT 241
            |.|.| .|...:.:.:|..:.:|   |......|.|  |....|...|:..|.....:.:.   |
  Fly   504 EAVTD-GAGLAQDQEMPIFRIDSRSGVISTRSSLDR--ETSDSYHLLVTAADLASAQSERR---T 562

  Fly   242 AT----------NFTTPHDLIFPHKPGIIMIPEDAKRGTELDYVIA--RKNPLFQKPVYLELWGS 294
            ||          |...|.   |..:...:.:|||...||| |..:|  |.....|        |:
  Fly   563 ATASVQVKVLDDNDNYPQ---FSERTYTVQVPEDQWGGTE-DNTVAHIRATDADQ--------GN 615

  Fly   295 PLFAIRQKIV--------SSETTEGTVFLLGPLDFEKQAMYHLTILANDAYAEPGQDSRNIAGME 351
            .. |||..|:        |.::..|.|.|:.|||:|....|.|.|.|.|.    |..||:.. .:
  Fly   616 NA-AIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDG----GSPSRSNT-TQ 674

  Fly   352 IVVIVQDVQDQPPVFTSAPPVTKLPPGILPGDKILQVHAEDGDKGNPREVRYGLVSENNPFTSFF 416
            ::|.|.|..|..|.|.::.....:...:..|..|::|.|.|.|:|...|:.|.:...::.|.  .
  Fly   675 LLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFP--L 737

  Fly   417 DINETSGEIFLMRPLE-----DIAFITHVGDPVLLTVIAEEVKVGRDEPPALASTVQLAFFLPDR 476
            .::..:|.:..::||:     ..||          .|:|::..|    ||..||: .:...:.|.
  Fly   738 AVDPRTGWVQTIKPLDREEQGRFAF----------QVVAKDGGV----PPKSASS-SVVITVQDV 787

  Fly   477 TNSPPYFENDHYVSRVDENAPHGTALTFV---DPYVPRVYDDDTGKNGVFSLTLLNNNGTFEISP 538
            .::.|.|...:|.:.|.|:.|.||.:|.|   ||      |:|:..:  :.:|..|..|.|.|:
  Fly   788 NDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDP------DEDSRLH--YEITTGNTRGRFAIT- 843

  Fly   539 NVAERSAGFLIRVRDNSMLDYEQQQSVQFQILAQELGPATNLSALVNVTVYIN--DVNDNAPVFE 601
              ::...| ||.:..:  |||:|::.....:.|.:.|..::     ..||:||  |.|:.||:||
  Fly   844 --SQNGRG-LITIAQS--LDYKQEKRFLLTVAATDSGGRSD-----TATVHINITDANNFAPIFE 898

  Fly   602 QPAYSVELPENMTAGTKVVQVLATDPDSGLGGKVRYTAILGYLN-TSLN---------LDAETGL 656
            ...||..:.|:...||.|:.|.|||.|.|:..::.|:     || .|:|         ::.:||.
  Fly   899 NAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYS-----LNEESINGLGSPDPFSINPQTGA 958

  Fly   657 ITVSTNKHGFDREVMPEYHLYVEARDMDGEGNRAQVPLIIKLIDVNDETPIFDKDLYEFILTHDL 721
            |..:.   ..|||....|.|.|.|:|...........:.|.:.||||..|.|...||:..:..|.
  Fly   959 IVTNA---PLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDA 1020

  Fly   722 MGFTTTAVIHAEDKDATAPNNEVRYEIINGNY-DNQFVLDKVTGELTVREKIHLRSKKNAKTRRR 785
            :..|:...:.|.|.| ...|..::|.:.:.:. |..||:|..:|.:                  |
  Fly  1021 LVGTSVIQVAASDPD-VGLNGRIKYLLSDRDIEDGSFVIDPTSGTI------------------R 1066

  Fly   786 RQAGSDDEDTDIFILTARAYDLGVPVRFSTTTIRV-------YPPESRKRSVKFVVPGHNPDKAK 843
            ...|.|.|...:|.|||.|.|.|.|...||..:::       .||......:...||.::|..:.
  Fly  1067 TNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSV 1131

  Fly   844 TEETLSALSGGKVYIHNIRPLSPDEP----------GAKDIPA----GNPGIKERSVVTATVI-Y 893
            .         |:::.|:     |||.          |..|..|    ..||.:...::|.|.: |
  Fly  1132 V---------GEIHAHD-----PDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDY 1182

  Fly   894 DSS 896
            :|:
  Fly  1183 EST 1185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad86C	NP_001247033.1	Cadherin_repeat	260..361	CDD:206637	34/110 (31%)
		Cadherin_repeat	372..469	CDD:206637	22/101 (22%)
		Cadherin_repeat	487..596	CDD:206637	32/113 (28%)
		Cadherin_repeat	605..703	CDD:206637	31/107 (29%)
		Cadherin_repeat	728..820	CDD:206637	24/92 (26%)
		PTZ00449	<1428..1918	CDD:185628
stan	NP_001260871.1	Cadherin_repeat	364..460	CDD:206637	4/12 (33%)
		Cadherin_repeat	468..577	CDD:206637	27/116 (23%)
		Cadherin_repeat	585..685	CDD:206637	34/114 (30%)
		Cadherin_repeat	693..790	CDD:206637	23/113 (20%)
		Cadherin_repeat	799..891	CDD:206637	31/110 (28%)
		Cadherin_repeat	901..1003	CDD:206637	32/109 (29%)
		Cadherin_repeat	1012..1108	CDD:206637	27/114 (24%)
		Cadherin_repeat	1118..1216	CDD:206637	17/82 (21%)
		EGF_CA	1483..1518	CDD:238011
		LamG	1558..1734	CDD:238058
		EGF	1760..1789	CDD:394967
		Laminin_G_2	1826..1944	CDD:460494
		TNFRSF	<1963..2061	CDD:473981
		EGF_Lam	2095..2140	CDD:214543
		HRM	2144..2200	CDD:397086
		GAIN	2290..2458	CDD:465137
		GPS	2743..2802	CDD:470616
		7tmB2_CELSR_Adhesion_IV	2809..3066	CDD:320557
		TM helix 1	2811..2836	CDD:320557
		TM helix 2	2845..2867	CDD:320557
		TM helix 3	2880..2907	CDD:320557
		TM helix 4	2919..2939	CDD:320557
		TM helix 5	2956..2985	CDD:320557
		TM helix 6	2997..3024	CDD:320557
		TM helix 7	3028..3053	CDD:320557