Protein Alignment Cad86C and Pcdh7

DIOPT Version :10

• Sequence 1: NP_001247033.1
• Gene: Cad86C / 41302
• FlyBaseID: FBgn0261053
• Length: 1949
• Species: Drosophila melanogaster
• Sequence 2: XP_063129415.1
• Gene: Pcdh7 / 360942
• RGDID: 1303209
• Length: 1275
• Species: Rattus norvegicus
• Alignment Length: 1125
• Identity: 230/1125 - (20%)
• Similarity: 431/1125 - (38%)
• Gaps: 266/1125 - (23%)

  Fly   306 SETTEG----TVFLLGPLDFEKQAMYHLTILANDAYAEPGQDSRNIAGMEIVVIVQDVQDQPPVF 366
            ::|.:|    .:.:.|.||.|::..|.||:...|. .:|.:.|:.|    :.|::.||.|..|.|
  Rat   249 ADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDG-GDPPRSSQAI----LRVLITDVNDNSPRF 308

  Fly   367 TSAPPVTKLPPGILPGDKILQVHAEDGDKGNPREVRYGLVSENNPFTSFFDINETSGEIFLMRPL 431
            ..:.....|.....||..|||:.|.|.|.|...::.|...:..........::||||.:.::..:
  Rat   309 EKSVYEADLAENSAPGTPILQLRATDLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRI 373

  Fly   432 --EDIAFITHVGDPVLLTVIAEEVKVGRDEPPAL-ASTVQLAFFLPDRTNSPPYFE--------- 484
              |::       :.:..||:|.:    |.:||.. .:||.|.  :.|..::.|..|
  Rat   374 DREEV-------NQLRFTVMARD----RGQPPKTDKATVVLN--IKDENDNVPSIEIRKIGRIPL 425

  Fly   485 NDHYVSRVDENAPHGTALTFVDPYVPRVYDDDTGKNGVFSLTLLNNNGTFEISPNVAERSAG--- 546
            .|. |:.|.|:....|.:..|     :|.|.|.|:|||.:.|:: .:..|::.|  |..:.|
  Rat   426 KDG-VANVAEDVLVDTPIALV-----QVSDRDQGENGVVTCTVV-GDVPFQLKP--ASDTEGDQN 481

  Fly   547 ----FLIRVRDNSMLDYEQQQSVQFQILAQELGPATNLSALVNVTVYINDVNDNAPVFEQPAYSV 607
                ||   ..::.||||..:.....|:|.:.| :.:||:..::.|.:.|.|||.|||.|....|
  Rat   482 KKKYFL---HTSAPLDYETTREFNVVIVAVDSG-SPSLSSNNSLVVKVGDTNDNPPVFGQSVVEV 542

  Fly   608 ELPENMTAGTKVVQVLATDPDSGLGGKVRY---TAILGYLNTSLNLDAETGLITVSTNKHGFDRE 669
            ..|||...|.:|..|||||.|||...::.|   ::::|    :..:|.::|.|.|:|   ..|||
  Rat   543 YFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMG----TFAIDPDSGDILVNT---VLDRE 600

  Fly   670 VMPEYHLYVEARDMDGEGNRAQVPLIIKLIDVNDETPIFDKDLYEFILTHDLMGFTTTAVIHAED 734
            ....|...|.|:|......:....:|:::.|.||..|.|.:|::.|.:..:|...:...::...|
  Rat   601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMD 665

  Fly   735 KDATAPNNEVRYEIINGNYDNQFVLDKVTGELTVREKIHLRSKKNAKTRRRRQAGSDDEDTDIFI 799
            .| ...|.|:...|...:  |.|.::..||  |:...:..                |.|....:.
  Rat   666 AD-KGRNAEMSLYIEENS--NIFSIENDTG--TIYSTMSF----------------DREHQTTYT 709

  Fly   800 LTARAYDLGVPVRFSTTTIRVY----------------------PPESRKRSV------------ 830
            ...:|.|.|.|.|.:|.|:.::                      ||.|..|:|
  Rat   710 FRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPRNISYTLLPPSSNVRTVVATVLATDSDDG 774

  Fly   831 -----KFVVPGHNPDKAKTEETLSALSG--GKVY-----IHNIRPLSPDEPGAKDIPAGNPGIKE 883
                 .:.:.|.||.|....::.|.:..  ||:.     :|.:           .:...:.|...
  Rat   775 INADLNYSIVGGNPFKLFEIDSTSGVVSLVGKLTQKHYGLHRL-----------VVQVNDSGQPS 828

  Fly   884 RSVVTATVIYDSSSVVDISEIQQRLSHHNNSYAIMPQDTSSTDTLTPLQTQYKAENKVLFWLLIL 948
            :|..|...::.:.||.:.:.|..::.  .:.:..:.||.:.       ...|:...:.|..::.:
  Rat   829 QSTTTLVHVFVNESVSNATVIDSQIV--RSLHTPLTQDIAG-------DPSYEISKQRLSIVIGV 884

  Fly   949 LATLVALTILILLLCCICSWCPLYGAATKRIVNISRTEDDVHLVHREMANGKQTKSVQVAEWMGR 1013
            :|.::.: |||:|:..:..:|   .:.:|......:.:.:.....::....|:.|..:..: ..:
  Rat   885 VAGIMTV-ILIILIVMMARYC---RSKSKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNK-KSK 944

  Fly  1014 RDAWSAEKPPDTRTKPTRWEFHDGREQLDE--DVGRGQDIGEGD-----RRHIQSA--------E 1063
            :..:|:....:. :||....:....|:|.:  .:||.:.:..|.     .||.:|:        .
  Rat   945 QPLYSSIVTVEA-SKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLH 1008

  Fly  1064 EQQRRVRIKHNRT-----------AKDDL-----HLNFHNSRTNLINDRDVYMEDVIENRDLAGD 1112
            .|......||...           |.|::     |.:.::.:|:....:.|   |.::..:..|.
  Rat  1009 PQSPTAGKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTSNKYSKQV---DTVQTTNPPGH 1070

  Fly  1113 RE---------HITRTRVNR----QEYARRKQYDSEVRHIDDDSMRRHEIDRGSDIDFNTAHNSL 1164
            .|         .:|.:.|::    .:.:.:..|||.:...:..|.:.....|...:...
  Rat  1071 IEESCKINPFRRVTFSVVSQPQDPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLP------ 1129

  Fly  1165 KSKRELFIKDGNVEILQLMTRDK------------TRDGLNLDD----DNIYVNVPLKPAGNLSH 1213
            :...|....||:|...:.|..|.            ||:   .|:    |:.::.|...|....|.
  Rat  1130 EDNYERTTPDGSVGEAEHMENDSRPLPDVALTGKCTRE---CDEYGHSDSCWMPVRTSPERKKSQ 1191

  Fly  1214 PQL---LMVDNTGKEILMRRFIEEQPDGKQII-------------REHYQIVPGATYI---QSMP 1259
            |:|   :.||..|.:       |:..:|:..|             ...|:....|::.   ::.|
  Rat  1192 PKLSTFMPVDERGSQ-------EKLANGEAAIMGDRNRNLLNKKLTSSYETFSAASFSKNEEANP 1249

  Fly  1260 NEVQQGSTLKGDTFPLGKSG 1279
            .::           ||.|:|
  Rat  1250 EDI-----------PLTKTG 1258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad86C	NP_001247033.1	Cadherin_repeat	260..361	CDD:206637	16/58 (28%)
		Cadherin_repeat	372..469	CDD:206637	24/99 (24%)
		Cadherin_repeat	487..596	CDD:206637	31/115 (27%)
		Cadherin_repeat	605..703	CDD:206637	30/100 (30%)
		Cadherin_repeat	728..820	CDD:206637	19/91 (21%)
		PTZ00449	<1428..1918	CDD:185628
Pcdh7	XP_063129415.1	None