Protein Alignment Cap-H2 and ncaph2

DIOPT Version :10

• Sequence 1: NP_650014.2
• Gene: Cap-H2 / 41289
• FlyBaseID: FBgn0037831
• Length: 960
• Species: Drosophila melanogaster
• Sequence 2: NP_001037964.1
• Gene: ncaph2 / 733729
• XenbaseID: XB-GENE-993063
• Length: 624
• Species: Xenopus tropicalis
• Alignment Length: 868
• Identity: 174/868 - (20%)
• Similarity: 278/868 - (32%)
• Gaps: 299/868 - (34%)

  Fly    41 DEQQDLASLVVLLEELSKNTDYSTDLRISLGYYIEELLRHCL----GRNDVS-RRSAIVAAGSAL 100
            |.:.....|:..:.:|:||  :..|:...||.|:|||.:.|:    |:..:: ..:|::..|||
 Frog     3 DAESRFTHLLQPIRDLTKN--WEVDVAAQLGEYLEELDQICISFDGGKTTMNFAEAALLIQGSA- 64

  Fly   101 QYCGKIYGDRVEYLCQVVEHQIEALLTSELQKETPSGSAAPEKNERRPEETRKRHPKKLTNKEVD 165
              |  ||..:||||..:|...::.:                 .|::|.::     |..:....||
 Frog    65 --C--IYSKKVEYLYSLVYQALDFI-----------------SNKKRDQQ-----PASVGADGVD 103

  Fly   166 PYLLTLEPKRFKTMSDDKRFNAAGFVKCTRNRTIEYLYQDHTPPNLWKHAPIVDPHNPYDQDEKK 230
                           .|..|       ..||...|:|..|          .|:||... :.|.||
 Frog   104 ---------------KDATF-------AHRNDEEEFLSLD----------DIIDPKKT-NVDIKK 135

  Fly   231 QYKMFTYHVEHRYNTLLPDIPFERLNLIKEYVHTNQVNTTEILNEHMTTKEYLDEYIALENQMLA 295
            ...:...::          :|...:.|:.                        .|....:|..|.
 Frog   136 DQVLHVVNI----------VPLTPMALVP------------------------PEETEKKNNPLC 166

  Fly   296 ARYGAIVTRRRRL-------VDSARFMEDNLDEGLAKKMCMDKNLPMDTNETVLIDQSLVDENSR 353
            :|.|.::..|:..       ..|..||.:     ||.|.      ||.      ..|.:......
 Frog   167 SRKGEVLASRKDFRMNTCTPHPSGAFMLE-----LAGKS------PMQ------FLQHIQHHEEA 214

  Fly   354 SLTTAESTMGISQAENSTLKSSEVEATLSVSHIENSLSDSQEENPPLSSTLAINESSVLDSTRVD 418
            ||...|.. .|.:.||..:::.:.:....|..::.|     :|..|.:.             ..|
 Frog   215 SLAQGEQN-AIPEGENDNMEAEKSDCADPVQVLQFS-----DEGAPAAE-------------NGD 260

  Fly   419 PIKDLTLDELLLIDSGISMEELSDIQ---MHTAGQSFDDEGVVLSDLEDQRQLSPMLQMVSPSME 480
            ....|.||:......| .:|:...|:   |.|     ::.|.||.:..:|:..|.
 Frog   261 GAGFLPLDDHDEAGDG-EVEQAEHIERRKMQT-----EERGYVLRERLEQKPASA---------- 309

  Fly   481 AKTLNIIEMDADLIMNVPREVSYPILLNVMGL-PIKRLRRKCIFKLPPEFDLFRQARLPIKREGQ 544
                            :..|.|.|    ..|| |.:....|                 |.|:
 Frog   310 ----------------IKNETSDP----WCGLDPFESCEEK-----------------PFKK--- 334

  Fly   545 QKSPTTPRTVLQIGREAPQNEREPGSPCSLEFDEDLNFLGF--------------RQRRPTFDSG 595
            .|..|.||   .|..:...|:|:...||.|:     :|:.:              |::.|||
 Frog   335 GKHYTLPR---GIAEDLSSNKRKRKLPCKLQ-----DFMKWFSSTHWDGSEAMKSRRKGPTF--- 388

  Fly   596 FDIEEPRVSSCVSTIGEVKTELEDEIEANTNNLTDASASDALNENVNDTKESGLGDSLAQELNAS 660
            .|:|       |.....:|..:              :|...|:..:.           ||.:...
 Frog   389 ADME-------VLYWKHIKERM--------------TAQRQLHRRMG-----------AQFVKEV 421

  Fly   661 TEPNAENNTAN--SSQLEVTATESSGTLSGLETTVDLGMESALVSSVLDLSTEPSAMDSNIINVT 723
            |..|.|....|  ....:....:..|.........|||            ...|:.:..
 Frog   422 TLLNQEEELVNPLEEPRDADYLDYDGPADDASDHEDLG------------ENIPACLRE------ 468

  Fly   724 QPDNSDLEISTVQDQDTLHDEADAN-DLSAETPNPIADSAVDDCSL-IRDWHRRLAPALEAAHER 786
            :|...|:|..|:.||.:..:....| :|........|...|  .|| :|:|..::.|.|:...||
 Frog   469 EPALGDIEPVTLHDQLSYEELVRRNVELFMANSQKYAQETV--LSLRVREWEDKMGPQLQEQEER 531

  Fly   787 QNFNIKDLGTEI-LDICKAGNRTATLADVMADKDPSIMCRYMLASLVLTNHGNVSLDFENRDKSK 850
            ..|:|.|.|..: ....|.| ...:.|.:||||:|..:||||||||.|.|      |:......|
 Frog   532 GAFDIHDYGDRLTAQFSKVG-EWRSFASLMADKEPYEVCRYMLASLQLAN------DYTVEVSQK 589

  Fly   851 P-----IDMSQFRMHLKSMKRME 868
            |     :|....|: |...|..|
 Frog   590 PGLHEGLDTMALRL-LSQQKAHE 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cap-H2	NP_650014.2	CNDH2_C	<769..862	CDD:465283	33/98 (34%)
ncaph2	NP_001037964.1	CNDH2_N	6..123	CDD:461866	37/177 (21%)
		CNDH2_M	147..272	CDD:435617	30/184 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..239		6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..287		8/48 (17%)
		CNDH2_C	317..606	CDD:465283	85/383 (22%)