Protein Alignment Cap-H2 and Cap-H2

DIOPT Version :10

• Sequence 1: NP_650014.2
• Gene: Cap-H2 / 41289
• FlyBaseID: FBgn0037831
• Length: 960
• Species: Drosophila melanogaster
• Sequence 2: XP_001688363.3
• Gene: Cap-H2 / 5667610
• VectorBaseID: AGAMI1_008303
• Length: 1160
• Species: Anopheles gambiae
• Alignment Length: 1015
• Identity: 219/1015 - (21%)
• Similarity: 358/1015 - (35%)
• Gaps: 328/1015 - (32%)

  Fly    96 AGSALQYCGKIYGDRVEYLCQVVEHQIEALLTSELQKETPSGSAAPEKNERRPEET--------- 151
            ||..:|...:|||.:|:||..::.|..:       .::.....|..||.|:..||.
Mosquito   121 AGMLIQCAAQIYGRKVDYLMDIIMHMCD-------DQKAREKKAQEEKKEKANEEKGAAGEAEVQ 178

  Fly   152 ------------RKR----HPKKLT----------NKEVDPYLLTLEP--KRFKTMSDDKRFNAA 188
                        |||    :|:.|:          |   |..|..||.  :...|:..|:|....
Mosquito   179 EEQAAAGGKTGGRKRAGKFNPQSLSDCFGDLEFTCN---DGKLAKLESLIRPVATVDVDRRTKVR 240

  Fly   189 GF--------VKCTRNRTIEYLYQDHTPPNLWKHAPIVDPHNP------------------YDQD 227
            ..        ...||.|..|.|.:......:   |||:..:..                  ||
Mosquito   241 QMQDLCAELRANPTRQRRQEILNRMRDDACI---APIMSSNGAALKSQILDLESGETIGTRYD-- 300

  Fly   228 EKKQYKMFTYHVEHRYNTLLPDIPFERLNLIKEYVHTNQVNTTEILNE-HMTTKEY--------- 282
                |::...:::.|..:|:.:...:|.        ..:.:..:.|:| |::.:|.
Mosquito   301 ----YQIHLNYIDGRTGSLIAEHDLKRF--------FQRCDVMDFLSEQHLSERERCTRLGMPAP 353

  Fly   283 LDEYIALENQM--------LAARYGAIVTRRRRLVDSARFMEDNLDEGLAKKMCMDKNLPMDTNE 339
            .|.....|.::        |:.||      |.:|.|:..|     |..|.:....:    .||:.
Mosquito   354 TDVLAQRERELKLYMPPEYLSNRY------RIKLHDTTDF-----DNALIQARVTN----YDTDP 403

  Fly   340 TVLIDQSLVDENSR----------------------SLTTAESTMGISQAENSTLKSSEVEATLS 382
            .:    ||:|..:|                      |:....:..|.|:..:|....|:.:....
Mosquito   404 IL----SLMDHEARAAVQLPAGDGDDVSARPRNVTSSIPNLIAANGSSKQPDSGKSDSQAQDDSG 464

  Fly   383 VSHIENSLSDSQEENPPLSSTLA---INESSV--LDSTRVDPIKDLTL-----DELLLIDSGI-- 435
            :.| |.|.::.::.:|..|..|:   .|||||  |:||:..  |||||     :....:||.:
Mosquito   465 IEH-ETSATEEEDSDPSFSGVLSSSRANESSVEELESTQEK--KDLTLSASDTNTSQNLDSTVKE 526

  Fly   436 --SMEELSDIQMHTAGQSFDDEGVVLSDLEDQRQLSPMLQMVSPSMEAKTLNIIEMDADLIMNVP 498
              |.::|.........:...|||:.: |.|...:..|:           .|..:|:.||..:...
Mosquito   527 LDSTDKLECTDTKAGPRLSVDEGIGV-DRESPPRTGPI-----------RLEDVEVKADSAVTFS 579

  Fly   499 REVSYP---------ILLNVMGLPIKRLRRKCIFKLPPEFDLFRQARLPI-KREGQQKS------ 547
            |.|.:|         ::.|:.|:|.:..|:...|.||.|   :|:.:|.: ||:.:.:.
Mosquito   580 RGVVFPRPAVLRPAKLVQNIFGIPDELARKHVQFTLPME---YRKMKLELAKRQEEWRKQMQHTI 641

  Fly   548 --------------PTTPRTVLQIG---------REAPQNEREPGSPCSLEFDEDLNFLGFRQRR 589
                          |:||.....:|         ::.|.|:|...:|...|...      .||::
Mosquito   642 ELHSLKPTAESLARPSTPDLEDFLGFDDDETDQPQQKPNNKRTKSAPACAELSP------ARQKK 700

  Fly   590 PT-----FDSGFDIEEPRVSSCVSTIGEVKTELEDEIEANTNNLTDASASDALNENVNDTKESGL 649
            |:     |: |||                    |:||         .||..|..|......|.
Mosquito   701 PSTPEPDFE-GFD--------------------EEEI---------LSARKAAEEWFKGMPEK-- 733

  Fly   650 GDSLAQELNASTEPNAENNTANSSQLEVTATESSGTLSGLETTVDL--GMESAL--VSSVLD-LS 709
                |:.|.:|     .|..|..|.|..|.|.:....||:..||:.  |.:|..  ||..|: |.
Mosquito   734 ----AKLLTSS-----PNRRAVGSSLPATPTRTLSCDSGISDTVERTNGKDSCTPPVSPRLEPLP 789

  Fly   710 TEPSAMDSNIINVTQPDNSDLEISTVQDQDTL-------------H-DEADANDLSAETPNPIAD 760
            .:..|.||:...|.:|...|   |...:::..             | |||:|.         |..
Mosquito   790 EDGGAADSDTEAVPRPTTPD---SVTNEEEPFAPGPAVQHEPLQEHTDEANAR---------IQQ 842

  Fly   761 S---AVDDCSLIRDWHRRLAPALEAAHERQNFNIKDLGTEILD----ICKAGNRTATLADVMADK 818
            |   |.:....:..|||:|.|.|..:.:|.:|:|...||:|:|    ....|....||..|:..|
Mosquito   843 SMHEAKERFDKVSAWHRKLKPILIESEKRNHFDIHAYGTDIIDTFDPTAPLGVEAITLERVLEHK 907

  Fly   819 DPSIMCRYMLASLVLTNHGNVSLDFENRDKSKPIDMSQFRMHLKSMKRM--------EINPEDDV 875
            .|....|:.|:.|:|.|..||.:..:|.|..:....|:..:.|.|.||.        |:.|.|..
Mosquito   908 PPHSTARFFLSMLMLANTNNVQICNKNPDPLRLSAASEIELRLLSRKRHHKELEALGELLPPDGD 972

  Fly   876 GNINAAQSKSTPRSK----------QLNDSAHKPRTSTTA 905
            |:..||..::..:.|          |..:....||..|.:
Mosquito   973 GHELAASDRNRQKRKNRKRKIVFEEQTGEQEDLPRADTAS 1012

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cap-H2	NP_650014.2	CNDH2_C	<769..862	CDD:465283	29/96 (30%)
Cap-H2	XP_001688363.3	None