Protein Alignment MED7 and MED7

DIOPT Version :10

• Sequence 1: NP_731500.1
• Gene: MED7 / 41288
• FlyBaseID: FBgn0051390
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_004261.1
• Gene: MED7 / 9443
• HGNCID: 2378
• Length: 233
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 119/228 - (52%)
• Similarity: 157/228 - (68%)
• Gaps: 23/228 - (10%)

  Fly     7 QVSSLPMPPERYIANYTDENIRRNRAPRPPPPPAQHEVYSMFGIQYNNDEM-IRSLESQNIKRLI 70
            |||:||.||.:||..||||||:...||:||||  ..:.|.|||.|:..|:: ||.||||.|:||.
Human     6 QVSALPPPPMQYIKEYTDENIQEGLAPKPPPP--IKDSYMMFGNQFQCDDLIIRPLESQGIERLH 68

  Fly    71 PIHFDRRKELKKLNHSLLVNFLDLIDFLILNPDSPRRTEKIDDISLLFVNMHHLLNEFRPHQARE 135
            |:.||.:|||:|||.|:|:|||||:|.||.:|.|.:|.||::|:.||||::|||:||:|||||||
Human    69 PMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARE 133

  Fly   136 TLRVMMEMQKRQRVETAARFQKHLERVREIVNTAFSALPVLDD-DDDSGGAKIKTEVDPLEA--- 196
            |||||||:|||||:|||.|||||||||.|::....::||  || .....|.::|||  |::|
Human   134 TLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLP--DDLPHSEAGMRVKTE--PMDADDS 194

  Fly   197 ------------NAAAKNDPSYQHDRMLCKLVD 217
                        |:..:.|...:.|..||.|:|
Human   195 NNCTGQNEHQRENSGHRRDQIIEKDAALCVLID 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MED7	NP_731500.1	Med7	8..166	CDD:461794	101/158 (64%)
MED7	NP_004261.1	Med7	7..164	CDD:461794	100/157 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..213		9/40 (23%)