Protein Alignment CG6345 and cdk5rap1

DIOPT Version :9

• Sequence 1: NP_650002.1
• Gene: CG6345 / 41271
• FlyBaseID: FBgn0037816
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_012827252.2
• Gene: cdk5rap1 / 549946
• XenbaseID: XB-GENE-5727595
• Length: 625
• Species: Xenopus tropicalis
• Alignment Length: 555
• Identity: 296/555 - (53%)
• Similarity: 394/555 - (70%)
• Gaps: 20/555 - (3%)

  Fly    26 SVTSSAAGQLKSEPAARATFLERIQRGPGFQDFFA-VKPASRL-KTDEEEHVDTSVPYLNSIDFN 88
            |.|||:...||    .:..|..::..||..:||.. .|||..: .||:|:    ..||:......
 Frog    77 STTSSSKETLK----RKEEFTSKLATGPQLKDFLVNNKPAETVSSTDDED----PPPYIIPSYSP 133

  Fly    89 GNGRKVHFEVYGCQMNTNDTEVVFSILKENGYLRCQEPEEADVIMLVTCAVRDGAEQRIRNRLKH 153
            ....|::.|.||||||.||||:.:|||::|||:|.....|||||:||||:||:.|||.|.|||:.
 Frog   134 SRNNKIYLETYGCQMNVNDTEIAWSILQQNGYVRTYTEAEADVILLVTCSVREKAEQTIWNRLQQ 198

  Fly   154 LRAMKNKRS-TRRHPLQLTLLGCMAERLKEKLLEQEQCVDVIAGPDSYKDLPRLLAISRHYGNSA 217
            |.|:|.||| |.|  :::.||||||||||:::|::|..||::||||:|:||||||::: ..|...
 Frog   199 LAALKRKRSKTSR--MRIGLLGCMAERLKQEILDKENLVDLVAGPDAYRDLPRLLSVA-ETGQQV 260

  Fly   218 INVLLSLDETYADVMPVRLNSESPTAFVSIMRGCDNMCTYCIVPFTRGRERSRPLASIVAEVKAL 282
            .|||||:||||||::||..::.|.:||||||||||||||||||||||||||||||.||:.||:.|
 Frog   261 ANVLLSVDETYADILPVHTSASSKSAFVSIMRGCDNMCTYCIVPFTRGRERSRPLQSILEEVRML 325

  Fly   283 AEQGVKEVTLLGQNVNSYRDRTAQEEQDSLKATPVP-GFSTVYKPKTGGTPFAALLRSVAQAVPD 346
            :.|||||||||||||||||| |:..:..:.::.|:. ||||:||.|.||..|..||..|:|..|:
 Frog   326 SSQGVKEVTLLGQNVNSYRD-TSSAQFPNAESPPLSRGFSTIYKHKKGGLRFVDLLDKVSQIDPE 389

  Fly   347 MRIRFTSPHPKDFSDEVLEVIRDHPNVCKQLHLPAQSGNTQVLERMRRGYSREAYLELVQHIRQF 411
            |||||||||||||.||||::|.:..|:|||:|:|||||:.:|||.||||||||.||:|:|:|::.
 Frog   390 MRIRFTSPHPKDFPDEVLQLIAERHNICKQIHIPAQSGSNKVLETMRRGYSREVYLDLIQNIQES 454

  Fly   412 LPNVGLSSDFICGFCGETEEEFQDTVSLIQQVQYNVAYLFAYSMREKTTAHRRYKDDVPINVKNE 476
            :|.|.||||||.|||.||||:...|:||::.|.||.|:|||||||:||.|:.|.:||||..||..
 Frog   455 IPGVSLSSDFITGFCEETEEDHLQTLSLLRTVSYNAAFLFAYSMRKKTRAYHRLQDDVPQEVKQR 519

  Fly   477 RLQRMVQVFREGATQLHRKMEGQEQLILIEGKSKRSDAHWFGRNDANIKVI---VPSIYVPISGD 538
            ||..::.||||.|.:::::..|..||:|:||.||||.....||||.|.|||   .|.: ..::.:
 Frog   520 RLAELIAVFREEAGRVNQRAVGSTQLVLVEGPSKRSPEELCGRNDGNTKVIFSEAPKV-GGLAQE 583

  Fly   539 STARKSFGVGDFLAVRIEESNSQVLKGTPLELSNI 573
            ::.:.....||::.|:|..|:||.||||.|.|:.:
 Frog   584 NSLQNRIQSGDYVLVKITSSSSQSLKGTLLGLTTL 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6345	NP_650002.1	PRK14329	88..570	CDD:237676	276/486 (57%)
		UPF0004	93..196	CDD:279287	59/103 (57%)
		TRAM	494..568	CDD:280171	30/76 (39%)
cdk5rap1	XP_012827252.2	PRK14329	132..615	CDD:237676	276/487 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	264	1.000	Domainoid score	I1894
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9502
Inparanoid	1	1.050	477	1.000	Inparanoid score	I1442
OMA	1	1.010	-	-		QHG54971
OrthoDB	1	1.010	-	-		D407532at33208
OrthoFinder	1	1.000	-	-		FOG0005052
OrthoInspector	1	1.000	-	-		oto103048
Panther	1	1.100	-	-	LDO	PTHR43020
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2454
SonicParanoid	1	1.000	-	-		X3577
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110