Protein Alignment Rfx and Rfx4

DIOPT Version :10

• Sequence 1: NP_001247023.2
• Gene: Rfx / 41266
• FlyBaseID: FBgn0020379
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: XP_006514176.1
• Gene: Rfx4 / 71137
• MGIID: 1918387
• Length: 745
• Species: Mus musculus
• Alignment Length: 528
• Identity: 180/528 - (34%)
• Similarity: 251/528 - (47%)
• Gaps: 96/528 - (18%)

  Fly   369 TGGGGASPDSDQSALGSSNKIAS------ATIKWLSRNYETADGVSLPRSTLYNHYMQHCSEHKL 427
            |..|..|.|.::.   ..|..||      ||::||..|||.|:||.:|||.||.||:..|.::..
Mouse    44 TSLGNVSNDENEE---KENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDT 105

  Fly   428 EPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNSQAMDDKQMLAAGYGPSSD 492
            :|||||||||:||..|..|.||||||||.||||||||.:|..|          |.....|  |..
Mouse   106 QPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESS----------QYYDVMY--SKK 158

  Fly   493 GTGGPGSGPMVSVTSSTAGQLTGSNGLGGGHGQRHSNGTKKHTFKPETYEACIQYIGDGTSALPS 557
            |...........||..|.           .:..|...||                      .||.
Mouse   159 GAAWVSETGKREVTKQTV-----------AYSPRSKLGT----------------------LLPD 190

  Fly   558 FPPI-ELNHSFNSELTLEDVDTFRGLYREHCESFLDAVLNLEFNTVEFLLRDFWRASDNNNLDEC 621
            ||.: :||  ..:.|..|.|.||..:||.||:..||.|:...|:.|:..|..||:....:.|.
Mouse   191 FPNVKDLN--LPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLP-- 251

  Fly   622 EEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLEIW 686
                         :...:.|...|...|...|:....|::|.||:::|::|||.||.|||.|:.|
Mouse   252 -------------VLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEW 303

  Fly   687 LCESMLGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLSDLNRVDFHNV 751
            |..::..:||.|..||......|.|.|||.||||||.||:|.|:.:.....|||.|...||..::
Mouse   304 LKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLSSI 368

  Fly   752 QEQAAWVSQCA----PAVVQRLESDFKAALQQQSSLEQWASWLQLVVESAMEEYNGK--PTYARA 810
            .:|..:..:.:    ..::.:|..:|...|::||.:|.:..||..:|:..:.:...|  .:..:.
Mouse   369 TKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKV 433

  Fly   811 ARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEH------------------ 857
            |:||||.||.:.:.:|||:||.||.||||||||.|:||:|:.||:|.
Mouse   434 AQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEG 498

  Fly   858 KIAEAQDK 865
            ..||||::
Mouse   499 STAEAQEE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rfx	NP_001247023.2	RFX_DNA_binding	392..468	CDD:460512	47/75 (63%)
Rfx4	XP_006514176.1	RFX_DNA_binding	68..146	CDD:460512	47/77 (61%)